Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204809076> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W3204809076 endingPage "110920" @default.
- W3204809076 startingPage "110920" @default.
- W3204809076 abstract "With an increasingly elderly population globally, the impacts of cerebrovascular diseases, such as stroke and dementia, become increasingly significant. Haemorrhagic transformation (HT) is one of the most common complications of ischaemic stroke that is caused by dysfunction of endothelial cells in the blood-brain barrier (BBB) and that can be exacerbated by thrombolytic therapy. Recent studies also suggest that HT can lead to an increase in intracranial pressure (ICP) and result in capillary compression. The aim of this study is to develop a mathematical model that can be used to simulate the consequence of HT over a range of vasculature length scales. We use a 2D vasculature model to investigate the severity of HT with different vascular geometry. The resulting model shows that the haematoma radius is approximately constant across different length scales (100-1000μm) and in good agreement with the available experimental data. In addition, this study identified that the effects of capillary compression do appear to have a significant impact on the leakage fraction of blood and hence act to restrain the development of a haematoma." @default.
- W3204809076 created "2021-10-11" @default.
- W3204809076 creator A5031436437 @default.
- W3204809076 creator A5056716007 @default.
- W3204809076 date "2021-12-01" @default.
- W3204809076 modified "2023-09-25" @default.
- W3204809076 title "Mathematical modelling of haemorrhagic transformation after ischaemic stroke" @default.
- W3204809076 cites W114501706 @default.
- W3204809076 cites W128151115 @default.
- W3204809076 cites W1921630717 @default.
- W3204809076 cites W1978969303 @default.
- W3204809076 cites W1981403363 @default.
- W3204809076 cites W1981888641 @default.
- W3204809076 cites W1989909055 @default.
- W3204809076 cites W1995574496 @default.
- W3204809076 cites W2024170683 @default.
- W3204809076 cites W2031751552 @default.
- W3204809076 cites W2035828045 @default.
- W3204809076 cites W2040387077 @default.
- W3204809076 cites W2046721810 @default.
- W3204809076 cites W2046996556 @default.
- W3204809076 cites W2055009621 @default.
- W3204809076 cites W2055142956 @default.
- W3204809076 cites W2055725056 @default.
- W3204809076 cites W2075638893 @default.
- W3204809076 cites W2080360981 @default.
- W3204809076 cites W2083426712 @default.
- W3204809076 cites W2084011927 @default.
- W3204809076 cites W2093412209 @default.
- W3204809076 cites W2113010634 @default.
- W3204809076 cites W2113231609 @default.
- W3204809076 cites W2117026514 @default.
- W3204809076 cites W2126427858 @default.
- W3204809076 cites W2134286344 @default.
- W3204809076 cites W2140958279 @default.
- W3204809076 cites W2150072302 @default.
- W3204809076 cites W2159821105 @default.
- W3204809076 cites W2286710809 @default.
- W3204809076 cites W2328908889 @default.
- W3204809076 cites W2528381731 @default.
- W3204809076 cites W2588242043 @default.
- W3204809076 cites W259079545 @default.
- W3204809076 cites W2767599678 @default.
- W3204809076 cites W2780505666 @default.
- W3204809076 cites W2802663173 @default.
- W3204809076 cites W3026119127 @default.
- W3204809076 cites W3090768114 @default.
- W3204809076 doi "https://doi.org/10.1016/j.jtbi.2021.110920" @default.
- W3204809076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34582828" @default.
- W3204809076 hasPublicationYear "2021" @default.
- W3204809076 type Work @default.
- W3204809076 sameAs 3204809076 @default.
- W3204809076 citedByCount "1" @default.
- W3204809076 countsByYear W32048090762023 @default.
- W3204809076 crossrefType "journal-article" @default.
- W3204809076 hasAuthorship W3204809076A5031436437 @default.
- W3204809076 hasAuthorship W3204809076A5056716007 @default.
- W3204809076 hasConcept C121332964 @default.
- W3204809076 hasConcept C126322002 @default.
- W3204809076 hasConcept C164705383 @default.
- W3204809076 hasConcept C2780645631 @default.
- W3204809076 hasConcept C2908647359 @default.
- W3204809076 hasConcept C3018755981 @default.
- W3204809076 hasConcept C541997718 @default.
- W3204809076 hasConcept C71924100 @default.
- W3204809076 hasConcept C97355855 @default.
- W3204809076 hasConcept C99454951 @default.
- W3204809076 hasConceptScore W3204809076C121332964 @default.
- W3204809076 hasConceptScore W3204809076C126322002 @default.
- W3204809076 hasConceptScore W3204809076C164705383 @default.
- W3204809076 hasConceptScore W3204809076C2780645631 @default.
- W3204809076 hasConceptScore W3204809076C2908647359 @default.
- W3204809076 hasConceptScore W3204809076C3018755981 @default.
- W3204809076 hasConceptScore W3204809076C541997718 @default.
- W3204809076 hasConceptScore W3204809076C71924100 @default.
- W3204809076 hasConceptScore W3204809076C97355855 @default.
- W3204809076 hasConceptScore W3204809076C99454951 @default.
- W3204809076 hasLocation W32048090761 @default.
- W3204809076 hasLocation W32048090762 @default.
- W3204809076 hasOpenAccess W3204809076 @default.
- W3204809076 hasPrimaryLocation W32048090761 @default.
- W3204809076 hasRelatedWork W2008851126 @default.
- W3204809076 hasRelatedWork W2011347913 @default.
- W3204809076 hasRelatedWork W2049397185 @default.
- W3204809076 hasRelatedWork W2049567231 @default.
- W3204809076 hasRelatedWork W2073151595 @default.
- W3204809076 hasRelatedWork W2074833529 @default.
- W3204809076 hasRelatedWork W2125804349 @default.
- W3204809076 hasRelatedWork W2159512267 @default.
- W3204809076 hasRelatedWork W2304633692 @default.
- W3204809076 hasRelatedWork W2399063111 @default.
- W3204809076 hasVolume "531" @default.
- W3204809076 isParatext "false" @default.
- W3204809076 isRetracted "false" @default.
- W3204809076 magId "3204809076" @default.
- W3204809076 workType "article" @default.