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- W3204812599 abstract "Introduction Transcranial alternating current stimulation (tACS) is a non-invasive brain stimulation technique allowing to induce changes in oscillatory activity. Theta activity has been reported to play a major role in maintenance of information in working memory (WM). Objectives The current study had the initial goal to check the effect of theta tACS on accuracy and resting state EEG in a set of match-to-sample WM tasks. Methods In the first experiment, we tested 31 participants in the WM task after 20-min tACS applied at Fpz and CPz at 6 Hz, 1 mA.). In the second experiment, we compared the after-effects and online effects of the stimulation in a sample of 25 individuals. Five similar 25-min blocks filled with the same working memory task were distributed over 3 days. We assessed the same group of participants in all three sessions. On the Training day, the participants performed one block without stimulation. On the Sham-Verum day (SV), the first block with Sham stimulation followed by the second block with Verum stimulation. On the Verum-Sham day (VS), the blocks order reversed. Results After-effects of the stimulation did not produce any significant changes either in behavior (accuracy in the task) or resting-state EEG (theta frequency band spectral power in the first experiment. In the second experiment, 6 Hz tACS delivered before the WM task was not able to produce any observable changes in working memory performance. The same hold true for online stimulation. Conclusions Theta frequency tACS applied to Fpz-CPz electrodes is not an efficient method to improve WM." @default.
- W3204812599 created "2021-10-11" @default.
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- W3204812599 date "2021-04-01" @default.
- W3204812599 modified "2023-10-18" @default.
- W3204812599 title "Working memory after and during 6 Hz transcranial alternating current stimulation" @default.
- W3204812599 doi "https://doi.org/10.1192/j.eurpsy.2021.1303" @default.
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