Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204865231> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W3204865231 endingPage "240" @default.
- W3204865231 startingPage "230" @default.
- W3204865231 abstract "Systemic lupus erythematous (SLE) is a multisystem autoimmune disorder. While studying the pathogenesis of SLE is prevalent, both infectious and non-infectious elements are regarded to exert an important impact on the disease's development.To explore the overall status of EBV, TLR7, TLR9, and IFN-α gene expression in 32 patients suffering from SLE and 32 healthy controls.Plasma and PBMCs were separated from fresh whole blood. To measure EBV DNA load and mRNA levels of IFN-a, TLR-7 and9 in PBMCs, molecular techniques were employed. The production of IFN-α, ds-DNA IgG antibody, and EBNA-1 IgG levels were also measured in plasma by ELISA.SLE patients showed significantly higher EBV load (p=0.001) and transcriptional levels of TLR7 (p=0.0001), IFN-α (p=0.0001), and TLR9 (p=0.0001) than controls. Moreover, the plasma levels of IFN-α (p=0.0002) and EBNA-1specific IgG antibodies (p=0.01) were significantly higher in SLE patients.The results stressed on the potential role of EBV infection and TLRs in SLE patients although more research is needed to determine the global impact that EBV infection can have on immune signature in patients with SLE." @default.
- W3204865231 created "2021-10-11" @default.
- W3204865231 date "2021-09-01" @default.
- W3204865231 modified "2023-10-14" @default.
- W3204865231 title "Overall Status of Epstein-Barr virus Infection, IFN-a, and TLR-7/9 in Patients with Systemic Lupus Erythematous." @default.
- W3204865231 doi "https://doi.org/10.22034/iji.2021.87648.1814" @default.
- W3204865231 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34596588" @default.
- W3204865231 hasPublicationYear "2021" @default.
- W3204865231 type Work @default.
- W3204865231 sameAs 3204865231 @default.
- W3204865231 citedByCount "2" @default.
- W3204865231 countsByYear W32048652312022 @default.
- W3204865231 countsByYear W32048652312023 @default.
- W3204865231 crossrefType "journal-article" @default.
- W3204865231 hasConcept C104317684 @default.
- W3204865231 hasConcept C126322002 @default.
- W3204865231 hasConcept C136449434 @default.
- W3204865231 hasConcept C137061746 @default.
- W3204865231 hasConcept C150194340 @default.
- W3204865231 hasConcept C159654299 @default.
- W3204865231 hasConcept C190727270 @default.
- W3204865231 hasConcept C202751555 @default.
- W3204865231 hasConcept C203014093 @default.
- W3204865231 hasConcept C2522874641 @default.
- W3204865231 hasConcept C2776709828 @default.
- W3204865231 hasConcept C2776912625 @default.
- W3204865231 hasConcept C2779075594 @default.
- W3204865231 hasConcept C2779134260 @default.
- W3204865231 hasConcept C2779138994 @default.
- W3204865231 hasConcept C2779836521 @default.
- W3204865231 hasConcept C2780942790 @default.
- W3204865231 hasConcept C55493867 @default.
- W3204865231 hasConcept C71924100 @default.
- W3204865231 hasConcept C86803240 @default.
- W3204865231 hasConcept C8891405 @default.
- W3204865231 hasConceptScore W3204865231C104317684 @default.
- W3204865231 hasConceptScore W3204865231C126322002 @default.
- W3204865231 hasConceptScore W3204865231C136449434 @default.
- W3204865231 hasConceptScore W3204865231C137061746 @default.
- W3204865231 hasConceptScore W3204865231C150194340 @default.
- W3204865231 hasConceptScore W3204865231C159654299 @default.
- W3204865231 hasConceptScore W3204865231C190727270 @default.
- W3204865231 hasConceptScore W3204865231C202751555 @default.
- W3204865231 hasConceptScore W3204865231C203014093 @default.
- W3204865231 hasConceptScore W3204865231C2522874641 @default.
- W3204865231 hasConceptScore W3204865231C2776709828 @default.
- W3204865231 hasConceptScore W3204865231C2776912625 @default.
- W3204865231 hasConceptScore W3204865231C2779075594 @default.
- W3204865231 hasConceptScore W3204865231C2779134260 @default.
- W3204865231 hasConceptScore W3204865231C2779138994 @default.
- W3204865231 hasConceptScore W3204865231C2779836521 @default.
- W3204865231 hasConceptScore W3204865231C2780942790 @default.
- W3204865231 hasConceptScore W3204865231C55493867 @default.
- W3204865231 hasConceptScore W3204865231C71924100 @default.
- W3204865231 hasConceptScore W3204865231C86803240 @default.
- W3204865231 hasConceptScore W3204865231C8891405 @default.
- W3204865231 hasIssue "3" @default.
- W3204865231 hasLocation W32048652311 @default.
- W3204865231 hasLocation W32048652312 @default.
- W3204865231 hasOpenAccess W3204865231 @default.
- W3204865231 hasPrimaryLocation W32048652311 @default.
- W3204865231 hasRelatedWork W1506194577 @default.
- W3204865231 hasRelatedWork W2015396406 @default.
- W3204865231 hasRelatedWork W2021720773 @default.
- W3204865231 hasRelatedWork W2084889692 @default.
- W3204865231 hasRelatedWork W2134106169 @default.
- W3204865231 hasRelatedWork W2143642734 @default.
- W3204865231 hasRelatedWork W2162154761 @default.
- W3204865231 hasRelatedWork W2560797679 @default.
- W3204865231 hasRelatedWork W2789922392 @default.
- W3204865231 hasRelatedWork W4309888487 @default.
- W3204865231 hasVolume "18" @default.
- W3204865231 isParatext "false" @default.
- W3204865231 isRetracted "false" @default.
- W3204865231 magId "3204865231" @default.
- W3204865231 workType "article" @default.