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• W3204966130 abstract "RNAs form secondary structures containing double-stranded base paired regions and single-stranded regions. Probing, detecting and modulating RNA structures and dynamics requires the development of molecular sensors that can differentiate the sequence and structure of RNAs present in viruses and cells, as well as in extracellular space. In this review, we summarize the recent progress on the development of chemically modified peptide nucleic acids (PNAs) for the selective recognition of double-stranded RNA (dsRNA) sequences over both single-stranded RNA (ssRNA) and double-stranded DNA (dsDNA) sequences. We also briefly discuss the applications of sequence-specific dsRNA-binding PNAs in sensing and stabilizing dsRNA structures and inhibiting dsRNA-protein interactions." @default.
• W3204966130 created "2021-10-11" @default.
• W3204966130 creator A5042296011 @default.
• W3204966130 creator A5062991118 @default.
• W3204966130 creator A5067358905 @default.
• W3204966130 date "2021-09-28" @default.
• W3204966130 modified "2023-10-10" @default.
• W3204966130 title "Mechanisms and applications of peptide nucleic acids selectively binding to double‐stranded RNA" @default.
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