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- W3204971470 abstract "Polymersomes that incorporate aggregation-induced emission (AIE) moieties are attractive inherently fluorescent nanoparticles with biomedical application potential for cell/tissue imaging and tracking, as well as phototherapeutics. An intriguing feature that has not been explored yet is their ability to adopt a range of asymmetric morphologies. Structural asymmetry allows nanoparticles to be exploited as active (motile) systems. Here, we present the design and preparation of AIE fluorophore integrated (AIEgenic) cucurbit-shaped polymersome nanomotors with enzyme-powered motility. The cucurbit scaffold was constructed via morphology engineering of biodegradable fluorescent AIE-polymersomes, followed by functionalization with enzymatic machinery via a layer-by-layer (LBL) self-assembly process. Because of the enzyme-mediated decomposition of chemical fuel on the cucurbit-like nanomotor surface, enhanced directed motion was attained, when compared with the spherical counterparts. These cucurbit-shaped biodegradable AIE-nanomotors provide a promising platform for the development of active delivery systems with potential for biomedical applications." @default.
- W3204971470 created "2021-10-25" @default.
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- W3204971470 date "2021-10-20" @default.
- W3204971470 modified "2023-10-15" @default.
- W3204971470 title "Cucurbit-Like Polymersomes with Aggregation-Induced Emission Properties Show Enzyme-Mediated Motility" @default.
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- W3204971470 doi "https://doi.org/10.1021/acsnano.1c07343" @default.
- W3204971470 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8613902" @default.
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- W3204971470 hasPublicationYear "2021" @default.
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