FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3204996171> ?p ?o ?g. }

• W3204996171 endingPage "127" @default.
• W3204996171 startingPage "113" @default.
• W3204996171 abstract "Excess risks of type 2 diabetes in UK South Asians (SA) and African Caribbeans (AC) compared with Europeans remain unexplained. We studied risks and determinants of type 2 diabetes in first- and second-generation (born in the UK) migrants, and in those of mixed ethnicity.Data from the UK Biobank, a population-based cohort of ~500,000 participants aged 40-69 at recruitment, were used. Type 2 diabetes was assigned using self-report and HbA1c. Ethnicity was both self-reported and genetically assigned using admixture level scores. European, mixed European/South Asian (MixESA), mixed European/African Caribbean (MixEAC), SA and AC groups were analysed, matched for age and sex to enable comparison. In the frames of this cross-sectional study, we compared type 2 diabetes in second- vs first-generation migrants, and mixed ethnicity vs non-mixed groups. Risks and explanations were analysed using logistic regression and mediation analysis, respectively.Type 2 diabetes prevalence was markedly elevated in SA (599/3317 = 18%) and AC (534/4180 = 13%) compared with Europeans (140/3324 = 4%). Prevalence was lower in second- vs first-generation SA (124/1115 = 11% vs 155/1115 = 14%) and AC (163/2200 = 7% vs 227/2200 = 10%). Favourable adiposity (i.e. lower waist/hip ratio or BMI) contributed to lower risk in second-generation migrants. Type 2 diabetes in mixed populations (MixESA: 52/831 = 6%, MixEAC: 70/1045 = 7%) was lower than in comparator ethnic groups (SA: 18%, AC: 13%) and higher than in Europeans (4%). Greater socioeconomic deprivation accounted for 17% and 42% of the excess type 2 diabetes risk in MixESA and MixEAC compared with Europeans, respectively. Replacing self-reported with genetically assigned ethnicity corroborated the mixed ethnicity analysis.Type 2 diabetes risks in second-generation SA and AC migrants are a fifth lower than in first-generation migrants. Mixed ethnicity risks were markedly lower than SA and AC groups, though remaining higher than in Europeans. Distribution of environmental risk factors, largely obesity and socioeconomic status, appears to play a key role in accounting for ethnic differences in type 2 diabetes risk." @default.
• W3204996171 created "2021-10-25" @default.
• W3204996171 creator A5006987054 @default.
• W3204996171 creator A5012612647 @default.
• W3204996171 creator A5014459421 @default.
• W3204996171 creator A5022288501 @default.
• W3204996171 creator A5025701947 @default.
• W3204996171 creator A5037318400 @default.
• W3204996171 creator A5038043213 @default.
• W3204996171 creator A5054032705 @default.
• W3204996171 creator A5057889252 @default.
• W3204996171 creator A5065179462 @default.
• W3204996171 creator A5073017363 @default.
• W3204996171 creator A5083404248 @default.
• W3204996171 creator A5091135967 @default.
• W3204996171 date "2021-10-20" @default.
• W3204996171 modified "2023-10-12" @default.
• W3204996171 title "Type 2 diabetes risks and determinants in second-generation migrants and mixed ethnicity people of South Asian and African Caribbean descent in the UK" @default.
• W3204996171 cites W1546952723 @default.
• W3204996171 cites W1891939305 @default.
• W3204996171 cites W1982243909 @default.
• W3204996171 cites W1995087258 @default.
• W3204996171 cites W2019794729 @default.
• W3204996171 cites W2026402776 @default.
• W3204996171 cites W2028396795 @default.
• W3204996171 cites W2046795558 @default.
• W3204996171 cites W2068733812 @default.
• W3204996171 cites W2073279551 @default.
• W3204996171 cites W2076300694 @default.
• W3204996171 cites W2083190671 @default.
• W3204996171 cites W2084695544 @default.
• W3204996171 cites W2085230521 @default.
• W3204996171 cites W2088005306 @default.
• W3204996171 cites W2097605596 @default.
• W3204996171 cites W2143843859 @default.
• W3204996171 cites W2144698381 @default.
• W3204996171 cites W2162666754 @default.
• W3204996171 cites W2329339334 @default.
• W3204996171 cites W2460039851 @default.
• W3204996171 cites W2520572981 @default.
• W3204996171 cites W2555361304 @default.
• W3204996171 cites W2723723801 @default.
• W3204996171 cites W2754444492 @default.
• W3204996171 cites W2791011305 @default.
• W3204996171 cites W2888341930 @default.
• W3204996171 cites W2892624068 @default.
• W3204996171 cites W2897956494 @default.
• W3204996171 cites W2946710786 @default.
• W3204996171 cites W2963506959 @default.
• W3204996171 cites W3009825875 @default.
• W3204996171 cites W3039137182 @default.
• W3204996171 cites W63959181 @default.
• W3204996171 doi "https://doi.org/10.1007/s00125-021-05580-7" @default.
• W3204996171 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34668055" @default.
• W3204996171 hasPublicationYear "2021" @default.
• W3204996171 type Work @default.
• W3204996171 sameAs 3204996171 @default.
• W3204996171 citedByCount "5" @default.
• W3204996171 countsByYear W32049961712022 @default.
• W3204996171 countsByYear W32049961712023 @default.
• W3204996171 crossrefType "journal-article" @default.
• W3204996171 hasAuthorship W3204996171A5006987054 @default.
• W3204996171 hasAuthorship W3204996171A5012612647 @default.
• W3204996171 hasAuthorship W3204996171A5014459421 @default.
• W3204996171 hasAuthorship W3204996171A5022288501 @default.
• W3204996171 hasAuthorship W3204996171A5025701947 @default.
• W3204996171 hasAuthorship W3204996171A5037318400 @default.
• W3204996171 hasAuthorship W3204996171A5038043213 @default.
• W3204996171 hasAuthorship W3204996171A5054032705 @default.
• W3204996171 hasAuthorship W3204996171A5057889252 @default.
• W3204996171 hasAuthorship W3204996171A5065179462 @default.
• W3204996171 hasAuthorship W3204996171A5073017363 @default.
• W3204996171 hasAuthorship W3204996171A5083404248 @default.
• W3204996171 hasAuthorship W3204996171A5091135967 @default.
• W3204996171 hasBestOaLocation W32049961711 @default.
• W3204996171 hasConcept C126322002 @default.
• W3204996171 hasConcept C134018914 @default.
• W3204996171 hasConcept C137403100 @default.
• W3204996171 hasConcept C144024400 @default.
• W3204996171 hasConcept C147077947 @default.
• W3204996171 hasConcept C149923435 @default.
• W3204996171 hasConcept C151956035 @default.
• W3204996171 hasConcept C19165224 @default.
• W3204996171 hasConcept C201903717 @default.
• W3204996171 hasConcept C2777180221 @default.
• W3204996171 hasConcept C2908647359 @default.
• W3204996171 hasConcept C555293320 @default.
• W3204996171 hasConcept C71924100 @default.
• W3204996171 hasConcept C72563966 @default.
• W3204996171 hasConcept C74909509 @default.
• W3204996171 hasConcept C99454951 @default.
• W3204996171 hasConceptScore W3204996171C126322002 @default.
• W3204996171 hasConceptScore W3204996171C134018914 @default.
• W3204996171 hasConceptScore W3204996171C137403100 @default.
• W3204996171 hasConceptScore W3204996171C144024400 @default.
• W3204996171 hasConceptScore W3204996171C147077947 @default.
• W3204996171 hasConceptScore W3204996171C149923435 @default.
• W3204996171 hasConceptScore W3204996171C151956035 @default.

• next