Matches in SemOpenAlex for { <https://semopenalex.org/work/W3205110092> ?p ?o ?g. }
- W3205110092 endingPage "6719" @default.
- W3205110092 startingPage "6707" @default.
- W3205110092 abstract "Although ovarian cancer is common, its prognosis remains poor because of drug resistance and early metastasis. Polysaccharides extracted from Bangia fuscopurpurea (BFP) are potential anti-cancer agents, but the mechanisms underlying their effects in human ovarian cancer remain unclear. Here, we investigated the mechanisms of action of BFP polysaccharides in A2780 ovarian cancer cells using cell migration, invasion, apoptosis, and autophagy assays. Transwell assays indicated that BFP inhibited cell migration and invasion. Flow cytometry analysis showed that BFP treatment induced apoptosis and reactive oxygen species production, while significantly reducing mitochondrial membrane potential. Reverse transcription-polymerase chain reaction and Western blot analyses revealed changes in the expression of apoptosis- and autophagy-related cellular mRNAs and proteins, respectively, following BFP treatment for 24 h. Transmission electron microscopy revealed that BFP induced autophagy in A2780 cells. These findings demonstrate that BFP may be useful for developing functional foods for cancer therapy." @default.
- W3205110092 created "2021-10-25" @default.
- W3205110092 creator A5036723563 @default.
- W3205110092 creator A5051626544 @default.
- W3205110092 creator A5056639915 @default.
- W3205110092 creator A5082091141 @default.
- W3205110092 creator A5084011111 @default.
- W3205110092 date "2021-10-10" @default.
- W3205110092 modified "2023-10-10" @default.
- W3205110092 title "Polysaccharides isolated from <i>Bangia fuscopurpurea</i> induce apoptosis and autophagy in human ovarian cancer A2780 cells" @default.
- W3205110092 cites W1751920243 @default.
- W3205110092 cites W1851763797 @default.
- W3205110092 cites W1970311282 @default.
- W3205110092 cites W1976921001 @default.
- W3205110092 cites W2014173742 @default.
- W3205110092 cites W2030092320 @default.
- W3205110092 cites W2034132952 @default.
- W3205110092 cites W2067299834 @default.
- W3205110092 cites W2069494381 @default.
- W3205110092 cites W2075843203 @default.
- W3205110092 cites W2096327969 @default.
- W3205110092 cites W2096934785 @default.
- W3205110092 cites W2333884632 @default.
- W3205110092 cites W2517036903 @default.
- W3205110092 cites W2529607059 @default.
- W3205110092 cites W2589635315 @default.
- W3205110092 cites W2747989445 @default.
- W3205110092 cites W2755719738 @default.
- W3205110092 cites W2766189673 @default.
- W3205110092 cites W2794123137 @default.
- W3205110092 cites W2803587120 @default.
- W3205110092 cites W2804993977 @default.
- W3205110092 cites W2810939825 @default.
- W3205110092 cites W2889302258 @default.
- W3205110092 cites W2889705835 @default.
- W3205110092 cites W2899906407 @default.
- W3205110092 cites W2901068463 @default.
- W3205110092 cites W2912342081 @default.
- W3205110092 cites W2940826723 @default.
- W3205110092 cites W2993927406 @default.
- W3205110092 cites W2997855104 @default.
- W3205110092 cites W3003183042 @default.
- W3205110092 cites W3040609627 @default.
- W3205110092 doi "https://doi.org/10.1002/fsn3.2621" @default.
- W3205110092 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34925800" @default.
- W3205110092 hasPublicationYear "2021" @default.
- W3205110092 type Work @default.
- W3205110092 sameAs 3205110092 @default.
- W3205110092 citedByCount "5" @default.
- W3205110092 countsByYear W32051100922022 @default.
- W3205110092 countsByYear W32051100922023 @default.
- W3205110092 crossrefType "journal-article" @default.
- W3205110092 hasAuthorship W3205110092A5036723563 @default.
- W3205110092 hasAuthorship W3205110092A5051626544 @default.
- W3205110092 hasAuthorship W3205110092A5056639915 @default.
- W3205110092 hasAuthorship W3205110092A5082091141 @default.
- W3205110092 hasAuthorship W3205110092A5084011111 @default.
- W3205110092 hasBestOaLocation W32051100921 @default.
- W3205110092 hasConcept C104317684 @default.
- W3205110092 hasConcept C121608353 @default.
- W3205110092 hasConcept C1491633281 @default.
- W3205110092 hasConcept C153911025 @default.
- W3205110092 hasConcept C190283241 @default.
- W3205110092 hasConcept C203522944 @default.
- W3205110092 hasConcept C2776415932 @default.
- W3205110092 hasConcept C2779013556 @default.
- W3205110092 hasConcept C2780427987 @default.
- W3205110092 hasConcept C48349386 @default.
- W3205110092 hasConcept C502942594 @default.
- W3205110092 hasConcept C54355233 @default.
- W3205110092 hasConcept C553184892 @default.
- W3205110092 hasConcept C55493867 @default.
- W3205110092 hasConcept C86803240 @default.
- W3205110092 hasConcept C95444343 @default.
- W3205110092 hasConcept C96232424 @default.
- W3205110092 hasConceptScore W3205110092C104317684 @default.
- W3205110092 hasConceptScore W3205110092C121608353 @default.
- W3205110092 hasConceptScore W3205110092C1491633281 @default.
- W3205110092 hasConceptScore W3205110092C153911025 @default.
- W3205110092 hasConceptScore W3205110092C190283241 @default.
- W3205110092 hasConceptScore W3205110092C203522944 @default.
- W3205110092 hasConceptScore W3205110092C2776415932 @default.
- W3205110092 hasConceptScore W3205110092C2779013556 @default.
- W3205110092 hasConceptScore W3205110092C2780427987 @default.
- W3205110092 hasConceptScore W3205110092C48349386 @default.
- W3205110092 hasConceptScore W3205110092C502942594 @default.
- W3205110092 hasConceptScore W3205110092C54355233 @default.
- W3205110092 hasConceptScore W3205110092C553184892 @default.
- W3205110092 hasConceptScore W3205110092C55493867 @default.
- W3205110092 hasConceptScore W3205110092C86803240 @default.
- W3205110092 hasConceptScore W3205110092C95444343 @default.
- W3205110092 hasConceptScore W3205110092C96232424 @default.
- W3205110092 hasIssue "12" @default.
- W3205110092 hasLocation W32051100921 @default.
- W3205110092 hasLocation W32051100922 @default.
- W3205110092 hasLocation W32051100923 @default.
- W3205110092 hasLocation W32051100924 @default.
- W3205110092 hasOpenAccess W3205110092 @default.