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• W3205113062 endingPage "1119" @default.
• W3205113062 startingPage "1096" @default.
• W3205113062 abstract "Closing the gap in knowledge on the cause of neurodegenerative disorders is paving the way toward innovative treatment strategies, among which gene therapy has emerged as a top candidate. Both conventional gene therapy and genome editing approaches are being developed, and a great number of human clinical trials are ongoing. Already 2 years ago, the first gene therapy for a neurodegenerative disease, spinal muscular atrophy type 1 (SMA1), obtained market approval. To realize such innovative strategies, gene therapy delivery tools are key assets. Here, we focus on recombinant adeno-associated virus (AAV) vectors and report on strategies to improve first-generation vectors. Current efforts focus on the viral capsid to modify the host-vector interaction aiming at increasing the efficacy of target cell transduction, at simplifying vector administration, and at reducing the risk of vector dose-related side effects." @default.
• W3205113062 created "2021-10-25" @default.
• W3205113062 creator A5062117290 @default.
• W3205113062 creator A5064539315 @default.
• W3205113062 creator A5087934177 @default.
• W3205113062 date "2021-10-01" @default.
• W3205113062 modified "2023-10-17" @default.
• W3205113062 title "Capsid-Engineering for Central Nervous System-Directed Gene Therapy with Adeno-Associated Virus Vectors" @default.
• W3205113062 cites W1153412892 @default.
• W3205113062 cites W1505196125 @default.
• W3205113062 cites W1518729035 @default.
• W3205113062 cites W1525995077 @default.
• W3205113062 cites W1756236371 @default.
• W3205113062 cites W1777527417 @default.
• W3205113062 cites W1821381892 @default.
• W3205113062 cites W1902159756 @default.
• W3205113062 cites W1964668661 @default.
• W3205113062 cites W1966374792 @default.
• W3205113062 cites W1966505487 @default.
• W3205113062 cites W1966513242 @default.
• W3205113062 cites W1967242914 @default.
• W3205113062 cites W1967720359 @default.
• W3205113062 cites W1968006472 @default.
• W3205113062 cites W1968713059 @default.
• W3205113062 cites W1969271703 @default.
• W3205113062 cites W1971284136 @default.
• W3205113062 cites W1973733861 @default.
• W3205113062 cites W1976329054 @default.
• W3205113062 cites W1977239997 @default.
• W3205113062 cites W1978221944 @default.
• W3205113062 cites W1979659851 @default.
• W3205113062 cites W1981130347 @default.
• W3205113062 cites W1981950767 @default.
• W3205113062 cites W1985810133 @default.
• W3205113062 cites W1985889861 @default.
• W3205113062 cites W1987453834 @default.
• W3205113062 cites W1988513056 @default.
• W3205113062 cites W1989674496 @default.
• W3205113062 cites W1990965764 @default.
• W3205113062 cites W1992250681 @default.
• W3205113062 cites W1994495694 @default.
• W3205113062 cites W1995972219 @default.
• W3205113062 cites W1997582178 @default.
• W3205113062 cites W2000118489 @default.
• W3205113062 cites W2000627935 @default.
• W3205113062 cites W2000695783 @default.
• W3205113062 cites W2002153634 @default.
• W3205113062 cites W2003523739 @default.
• W3205113062 cites W2003867647 @default.
• W3205113062 cites W2006534560 @default.
• W3205113062 cites W2007261697 @default.
• W3205113062 cites W2009285158 @default.
• W3205113062 cites W2009681413 @default.
• W3205113062 cites W2009792531 @default.
• W3205113062 cites W2013935392 @default.
• W3205113062 cites W2025343661 @default.
• W3205113062 cites W2033535780 @default.
• W3205113062 cites W2033689077 @default.
• W3205113062 cites W2034060287 @default.
• W3205113062 cites W2034197352 @default.
• W3205113062 cites W2035781263 @default.
• W3205113062 cites W2037962246 @default.
• W3205113062 cites W2038147156 @default.
• W3205113062 cites W2039583977 @default.
• W3205113062 cites W2042259141 @default.
• W3205113062 cites W2044333152 @default.
• W3205113062 cites W2045600222 @default.
• W3205113062 cites W2046566574 @default.
• W3205113062 cites W2047388966 @default.
• W3205113062 cites W2047608515 @default.
• W3205113062 cites W2047848268 @default.
• W3205113062 cites W2048456201 @default.
• W3205113062 cites W2053218323 @default.
• W3205113062 cites W2055792279 @default.
• W3205113062 cites W2056144642 @default.
• W3205113062 cites W2057955115 @default.
• W3205113062 cites W2062840171 @default.
• W3205113062 cites W2064074518 @default.
• W3205113062 cites W2066522660 @default.
• W3205113062 cites W2067204822 @default.
• W3205113062 cites W2068130700 @default.
• W3205113062 cites W2069663641 @default.
• W3205113062 cites W2070360032 @default.
• W3205113062 cites W2070754430 @default.
• W3205113062 cites W2074766632 @default.
• W3205113062 cites W2075953769 @default.
• W3205113062 cites W2078555248 @default.
• W3205113062 cites W2079335891 @default.
• W3205113062 cites W2086106239 @default.
• W3205113062 cites W2087185853 @default.
• W3205113062 cites W2088212973 @default.
• W3205113062 cites W2089217804 @default.
• W3205113062 cites W2090256568 @default.
• W3205113062 cites W2090661761 @default.
• W3205113062 cites W2091504719 @default.
• W3205113062 cites W2092420017 @default.
• W3205113062 cites W2098274109 @default.
• W3205113062 cites W2098414451 @default.

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