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- W3205200233 abstract "Deficits in emotion regulation (ER) have been found in persons with autism spectrum disorder (ASD), and they are less likely to employ adaptive ER strategies. However, the underlying mechanism for this remains unclear. The present study had a total of 454 college students complete the Autism Spectrum Quotient (AQ), the Dysexecutive Questionnaire (DEX), and the Emotional Regulation Questionnaire (ERQ), and identified their FKBP5 gene rs1360780 genotypes. The AQ total score, the attention switching subscale of the AQ, and executive dysfunction (as measured by the DEX) negatively predicted cognitive reappraisal on the ERQ. Executive dysfunction mediated the relationship between the AQ total score and cognitive reappraisal. The results found the FKBP5 rs1360780 (C carriers vs. TT genotype) moderated the relationship between the AQ total score and executive dysfunction, and the relationship between executive dysfunction and cognitive reappraisal. The findings indicate poor emotion regulation may be inherent in autistic traits, and there is a joint contribution of executive dysfunction and the FKBP5 rs1360780 to deficits in emotion regulation." @default.
- W3205200233 created "2021-10-25" @default.
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- W3205200233 date "2022-02-01" @default.
- W3205200233 modified "2023-10-07" @default.
- W3205200233 title "Associations of autistic traits, executive dysfunction and the FKBP5 gene with emotion regulation in Chinese college students" @default.
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- W3205200233 doi "https://doi.org/10.1016/j.paid.2021.111293" @default.
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