Matches in SemOpenAlex for { <https://semopenalex.org/work/W3205285540> ?p ?o ?g. }
- W3205285540 endingPage "119" @default.
- W3205285540 startingPage "107" @default.
- W3205285540 abstract "PurposeTo verify the dose-response relation between the degree of myopia and open-angle glaucoma (OAG) riskDesignDose-response meta-analysis.MethodsWe searched the PubMed, EMBASE, and Cochrane Library databases for population-based studies published until November 30, 2020, and reporting on both myopia and OAG. Random-effect models generated pooled odds ratios (OR) and 95% CIs. Results robustness was confirmed by influence and subgroup analyses. A 2-stage dose-response meta-analysis calculated the OAG risk per unit dose of myopia (spherical equivalent [SE] decrease of 1 diopter [D]) and examined the relationship pattern.ResultsThe meta-analysis comprised 24 studies in 11 countries (514,265 individuals). The pooled OR of any myopia degree's association with OAG was 1.88 (95% CI, 1.66-2.13; I2 = 53%). The OR differences based on ethnicity (Asians vs Westerners) or 5 geographic areas were not statistically significant (P = .80 and P = .06, respectively). The pooled ORs of the associations between low, moderate, moderate-to-high, high myopia, and OAG were 1.50 (95% CI, 1.29-1.76), 1.69 (95% CI, 1.33-2.15), 2.27 (95% CI, 1.74-2.96), and 4.14 (95% CI, 2.57-6.69), respectively. According to the dose-response meta-analysis, the pooled OR (per SE 1-D change) was 1.21 (95% CI, 1.15-1.28). The OAG risk accelerated at approximately −6 D, and further accelerated from −8 D, showing a nonlinear concave upward slope (P = .03).ConclusionsFor each unit (1-D) increase in myopia, the risk of glaucoma increases by approximately 20%. The risk more steeply increases in high-degree myopia, representing a significant nonlinear relationship. To verify the dose-response relation between the degree of myopia and open-angle glaucoma (OAG) risk Dose-response meta-analysis. We searched the PubMed, EMBASE, and Cochrane Library databases for population-based studies published until November 30, 2020, and reporting on both myopia and OAG. Random-effect models generated pooled odds ratios (OR) and 95% CIs. Results robustness was confirmed by influence and subgroup analyses. A 2-stage dose-response meta-analysis calculated the OAG risk per unit dose of myopia (spherical equivalent [SE] decrease of 1 diopter [D]) and examined the relationship pattern. The meta-analysis comprised 24 studies in 11 countries (514,265 individuals). The pooled OR of any myopia degree's association with OAG was 1.88 (95% CI, 1.66-2.13; I2 = 53%). The OR differences based on ethnicity (Asians vs Westerners) or 5 geographic areas were not statistically significant (P = .80 and P = .06, respectively). The pooled ORs of the associations between low, moderate, moderate-to-high, high myopia, and OAG were 1.50 (95% CI, 1.29-1.76), 1.69 (95% CI, 1.33-2.15), 2.27 (95% CI, 1.74-2.96), and 4.14 (95% CI, 2.57-6.69), respectively. According to the dose-response meta-analysis, the pooled OR (per SE 1-D change) was 1.21 (95% CI, 1.15-1.28). The OAG risk accelerated at approximately −6 D, and further accelerated from −8 D, showing a nonlinear concave upward slope (P = .03). For each unit (1-D) increase in myopia, the risk of glaucoma increases by approximately 20%. The risk more steeply increases in high-degree myopia, representing a significant nonlinear relationship." @default.
- W3205285540 created "2021-10-25" @default.
- W3205285540 creator A5002605667 @default.
- W3205285540 creator A5007825869 @default.
- W3205285540 creator A5035709059 @default.
- W3205285540 creator A5041387187 @default.
- W3205285540 creator A5054588294 @default.
- W3205285540 date "2022-04-01" @default.
- W3205285540 modified "2023-10-16" @default.
- W3205285540 title "Degree of Myopia and Glaucoma Risk: A Dose-Response Meta-analysis" @default.
- W3205285540 cites W1115893768 @default.
- W3205285540 cites W1539221256 @default.
- W3205285540 cites W1584824855 @default.
- W3205285540 cites W1590050345 @default.
- W3205285540 cites W1605393132 @default.
- W3205285540 cites W1854833362 @default.
- W3205285540 cites W1959475862 @default.
- W3205285540 cites W1964435302 @default.
- W3205285540 cites W1967629015 @default.
- W3205285540 cites W1979423827 @default.
- W3205285540 cites W1984412273 @default.
- W3205285540 cites W1986181912 @default.
- W3205285540 cites W1986218947 @default.
- W3205285540 cites W1992653534 @default.
- W3205285540 cites W1994562860 @default.
- W3205285540 cites W1999497297 @default.
- W3205285540 cites W1999641044 @default.
- W3205285540 cites W2011725067 @default.
- W3205285540 cites W2011796275 @default.
- W3205285540 cites W2024592965 @default.
- W3205285540 cites W2030904560 @default.
- W3205285540 cites W2031497817 @default.
- W3205285540 cites W2032737645 @default.
- W3205285540 cites W2038047187 @default.
- W3205285540 cites W2038439194 @default.
- W3205285540 cites W2057266151 @default.
- W3205285540 cites W2065619097 @default.
- W3205285540 cites W2074306573 @default.
- W3205285540 cites W2088756116 @default.
- W3205285540 cites W2089486552 @default.
- W3205285540 cites W2091642517 @default.
- W3205285540 cites W2097237664 @default.
- W3205285540 cites W2104657845 @default.
- W3205285540 cites W2108833375 @default.
- W3205285540 cites W2110907428 @default.
- W3205285540 cites W2111865007 @default.
- W3205285540 cites W2125435699 @default.
- W3205285540 cites W2126521036 @default.
- W3205285540 cites W2126930838 @default.
- W3205285540 cites W2134289380 @default.
- W3205285540 cites W2135806783 @default.
- W3205285540 cites W2139077400 @default.
- W3205285540 cites W2157823046 @default.
- W3205285540 cites W2159135906 @default.
- W3205285540 cites W2166045927 @default.
- W3205285540 cites W2170273238 @default.
- W3205285540 cites W2263495255 @default.
- W3205285540 cites W2287734588 @default.
- W3205285540 cites W2427977919 @default.
- W3205285540 cites W2737512989 @default.
- W3205285540 cites W2740924709 @default.
- W3205285540 cites W3019600791 @default.
- W3205285540 cites W3031422131 @default.
- W3205285540 cites W4255271122 @default.
- W3205285540 cites W4294215472 @default.
- W3205285540 cites W65360543 @default.
- W3205285540 doi "https://doi.org/10.1016/j.ajo.2021.10.007" @default.
- W3205285540 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34648776" @default.
- W3205285540 hasPublicationYear "2022" @default.
- W3205285540 type Work @default.
- W3205285540 sameAs 3205285540 @default.
- W3205285540 citedByCount "32" @default.
- W3205285540 countsByYear W32052855402021 @default.
- W3205285540 countsByYear W32052855402022 @default.
- W3205285540 countsByYear W32052855402023 @default.
- W3205285540 crossrefType "journal-article" @default.
- W3205285540 hasAuthorship W3205285540A5002605667 @default.
- W3205285540 hasAuthorship W3205285540A5007825869 @default.
- W3205285540 hasAuthorship W3205285540A5035709059 @default.
- W3205285540 hasAuthorship W3205285540A5041387187 @default.
- W3205285540 hasAuthorship W3205285540A5054588294 @default.
- W3205285540 hasBestOaLocation W32052855401 @default.
- W3205285540 hasConcept C118487528 @default.
- W3205285540 hasConcept C126322002 @default.
- W3205285540 hasConcept C156957248 @default.
- W3205285540 hasConcept C187960798 @default.
- W3205285540 hasConcept C259533 @default.
- W3205285540 hasConcept C2776148792 @default.
- W3205285540 hasConcept C2776478404 @default.
- W3205285540 hasConcept C2778257484 @default.
- W3205285540 hasConcept C2778527774 @default.
- W3205285540 hasConcept C2781135284 @default.
- W3205285540 hasConcept C2908647359 @default.
- W3205285540 hasConcept C71924100 @default.
- W3205285540 hasConcept C95190672 @default.
- W3205285540 hasConcept C99454951 @default.
- W3205285540 hasConceptScore W3205285540C118487528 @default.
- W3205285540 hasConceptScore W3205285540C126322002 @default.