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- W3205292681 abstract "Recent studies suggest cognitive, emotional, and behavioral impairments occur in patients after SARS-CoV-2 infection. However, studies are still few and to our knowledge, without a control group. This study aims to assess the prevalence of neuropsychological and neuropsychiatric impairment in patients after hospitalization. We enrolled 17 Covid+ patients (M/F:12/5; age: 53.59 ± 12.32 yrs; education 11.88 ± 3.6 yrs) who needed hospitalization but no IC, about 18 days post dismission, and 17 Covid- matched controls (M/F:11/6; age: 53.82 ± 12.34 yrs; education: 12.59 ± 3.77 yrs). Neuropsychological and neuropsychiatric assessments were conducted via tele neuropsychology with the following tests: MMSE, CPM47, RAVLT, CDT, Digit-Span Forward/Backward, Verbal fluencies; BDI-II, STAI, AES. People with previous cognitive impairment, neurological or psychiatric conditions were excluded. Clinical and demographics were collected. Comparison between groups was conducted using parametric or non-parametric tests according to data distribution (T-test, Mann Withney-U test; Chisquare). Among Covid+, 82% had at least one pathological test (vs 30% in Covid-; p=0,001) and significantly worst performaces than Covid- in Digit Backward (4.05 ± 1.2 vs 4.8 ± 1 p = 0.046), RAVLTlearning (42 ± 9.4 vs 49.4 ± 7.9 p = 0.018), RAVLTrecall (8,1±2,9 vs 10.6±2,5 p=0,013), Semantic Fluencies (43.7 ± 7.3 vs 50.6 ± 6.8 p = 0.008). STAI-Y2 was higher in Covid- (32.6 ± 7.4 vs 40.5 ± 7.9 p =0.005). Patients Covid+ assessed by tele neuropsychology showed a vulnerability in some memory end executive functions (working memory, learning and recall, semantic memory). Intriguingly, anxiety was higher in the control group. Our findings, therefore, confirm an impact of Covid-19 on cognition even in patients who did not need IC. Follow-up is needed to evaluate if these difficulties can recover with time." @default.
- W3205292681 created "2021-10-25" @default.
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- W3205292681 date "2021-10-01" @default.
- W3205292681 modified "2023-10-17" @default.
- W3205292681 title "Cognitive and neuropsychiatric features of COVID-19 patients after hospital dismission: An Italian pilot study" @default.
- W3205292681 doi "https://doi.org/10.1016/j.jns.2021.119791" @default.
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