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- W3205420152 abstract "Inherited thrombophilic disorders are well-established predisposing factors for venous thromboembolism, but their role in arterial ischaemic stroke is uncertain. The exact mechanism of arterial thrombosis in thrombophilias remains elusive. Herein, we report a case of a 30-year-old woman who was admitted to our facility with sudden-onset right-sided ptosis and ophthalmoplegia. Detailed clinical features, neuroimaging and laboratory evaluation clinched the diagnosis of ischaemic stroke in midbrain due to microvascular obstruction associated with isolated protein S deficiency. She was treated with oral anticoagulant (warfarin) and physiotherapy; without any improvement of her symptoms at 2 months of follow-up. A high index of clinical suspicion is needed in any case of young ischaemic stroke in absence of common cardiac and vascular risk factors, to recognise the presence of inherited thrombophilia." @default.
- W3205420152 created "2021-10-25" @default.
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- W3205420152 date "2021-10-01" @default.
- W3205420152 modified "2023-10-18" @default.
- W3205420152 title "Midbrain infarction in inherited protein S deficiency: a rare association" @default.
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- W3205420152 doi "https://doi.org/10.1136/bcr-2021-246073" @default.
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