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- W3205420382 abstract "Reactive oxygen species play a significant role in regulating the main functions of the cell both in the normal conditions and when exposing the cell to exogenous and endogenous factors under electromagnetic and radiation emission at various levels of solar activity. The research studied the impact of low-intensity alternating magnetic field; the intensity level is comparable to the geomagnetic field, in the frequency range from 3 to 60 Hz and γ-radiation on the generation of the most stable ROS which are hydrogen peroxide, in vitro. A degree of oxidative DNA damage in the blood serum of health donors, after being exposed to the alternating magnetic field, was investigated by determining the content of 8- hydroxy-2-deoxyguanosine (8-OHdG) in the blood serum and DNA single breaks in the lymphocytes. An increase of the content of 8-OHdG in DNA by a factor of 1.5 – 2 in comparison with non-emitted samples, and non-linear change in the level of lipid peroxide in the blood serum with maxima at MF frequencies of 8 and 50 Hz. In lymphocytes are observed. When exposed to gamma radiation, the number of single-strand breaks (SSB) of DNA increased with increasing exposure time from 44.3 ± 0.4% (irradiation for 30 minutes) to 68.3 ± 0.8% (irradiation for 90 minutes) compared to the control samples. It is concluded that the obtained effects can be associated with the generation of reactive oxygen species in the aquatic environment with variations in solar activity and affect the adaptive capabilities of the human body as a whole." @default.
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- W3205420382 date "2021-09-01" @default.
- W3205420382 modified "2023-09-25" @default.
- W3205420382 title "Reactive oxygen species, DNA damage and Solar-Earth communications" @default.
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- W3205420382 doi "https://doi.org/10.1088/1755-1315/853/1/012007" @default.
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