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• W3205451373 abstract "TOPIC: Obstructive Lung Diseases TYPE: Original Investigations PURPOSE: Despite the growing popularity of e-cigarette use, only few studies have evaluated the relationship between e-cigarette use and the development of obstructive pulmonary diseases. The aim of this study is to examine the relationship between e-cigarette use and asthma or COPD in the United States. METHODS: Using pooled 2016, 2017 and 2018 Behavioral Risk Factor Surveillance System (BRFSS) data, 741,870 participants aged 18 years and above were studied. We estimated the crude odds-ratio in a bivariate analysis between e-cigarette use and asthma or COPD as the outcome. Multivariable logistic regression and forward change-in-estimate approach using the 10% rule was used to control for confounding by age, sex, race, income, cigarette smoking and body mass index (for asthma only). The additional effect of age, race and sex on the association between e-cigarettes and these pulmonary diseases was also determined using stratified analysis. All analyses were carried out using SAS version 9.4 (SAS Institute Inc., Cary, NC, USA). RESULTS: Of 741,870 participants, 32,114 (4.3%) were classified as current e-cigarette users and 709,756 (95.7%) as never users. Current use of e-cigarettes was associated with a higher odds of developing asthma and COPD in both unadjusted (asthma: OR=1.37, 95% CI=1.29, 1.46; COPD: OR=1.69, 95% CI=1.59, 1.80) and adjusted analyses (asthma: OR=1.21, 95% CI=1.13, 1.29; COPD: OR=1.43, 95% CI=1.34, 1.54). The relationship between e-cigarette use and asthma was modified by age, sex and race with the highest odds observed in individuals aged between 55-64 years (OR=1.42, 95% CI=1.22, 1.64), females compared to males (OR=1.33, 95% CI=1.22, 1.45) and Hispanic-Americans (OR=1.62, 95% CI=1.28, 2.05) compared to other races. For COPD, similar results were observed with a greater female predominance (OR=1.57, 95% CI=1.43, 1.71) and the highest odds in Hispanic-Americans (OR=1.71, 95% CI=1.28, 2.28). However, unlike asthma, individuals 65 years and above had a higher odds of developing COPD with e-cigarette use compared to younger adults (OR=2.09, 95% CI=1.81, 2.41). CONCLUSIONS: Our findings suggest that the use of e-cigarette increases the odds of developing asthma and COPD in general with a relatively higher odds in older adults, females and Hispanic-Americans. More research is required especially in the form of empirical studies to truly characterize this relationship with implications for the formulation of health policy. CLINICAL IMPLICATIONS: The clinical implications of our research are:- Encourage healthcare professionals to monitor patient's healths to avoid future risks by following up with patients who smoke e-cigarette regularly to see if they develop signs and symptoms of chronic diseases that are associated with smoking such as asthma and COPD.-Help in early COPD prevention and prevention of asthma exacerbations in youth.-In Clinics, smoking cessation advice should also include the use of e-cigarettes. This is important because e-cigarette has been perceived to be a safer alternative to combustible tobacco use despite their detriments to health.-Encourage improved access to smoking cessation treatments for minority groups to reduce the likelihood of their use of e-cigarettes as a smoking cessation option. DISCLOSURES: No relevant relationships by Ayodele AJAYI, source=Web Response No relevant relationships by Chisom Asuzu, source=Admin input No relevant relationships by Omofolarin Babayale, source=Web Response No relevant relationships by Sarpong Boateng, source=Web Response No relevant relationships by Omosefe Ogbeifun, source=Web Response No relevant relationships by Oyeyemi Olaniran, source=Web Response No relevant relationships by Emmanuella Onaku, source=Web Response" @default.
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• W3205451373 date "2021-10-01" @default.
• W3205451373 modified "2023-09-25" @default.
• W3205451373 title "THE ASSOCIATION BETWEEN ELECTRONIC CIGARETTE USE AND OBSTRUCTIVE PULMONARY DISEASES" @default.
• W3205451373 doi "https://doi.org/10.1016/j.chest.2021.07.1681" @default.
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