FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3205526013> ?p ?o ?g. }

• W3205526013 endingPage "201" @default.
• W3205526013 startingPage "195" @default.
• W3205526013 abstract "Sepsis and bloodstream infection are associated with significant morbidity and mortality, and early effective antimicrobial therapy has been demonstrated to improve patient outcomes. Traditional culture-based methods, however, have several limitations that hamper a prompt diagnosis in bloodstream infection, including long turnaround times and limited sensitivity. In recent years, advances have been made in the development of several technologies that allow the identification of pathogens and their resistance markers directly from whole blood, possibly representing promising alternatives to conventional culture-based methods.To review the currently commercially available emerging assays for the diagnosis of bloodstream infections directly from whole blood, including their performance and the available data about their impact on patient outcome.Peer-reviewed publications relevant to the topic have been searched through PubMed; manufacturers' websites have also been consulted as a data source.We have reviewed available data about the following technologies: multiplex real-time PCR working directly from whole blood (Magicplex Sepsis Real-Time test, Seegene), PCR combined with T2 Magnetic Resonance (T2Candida and T2Bacteria panel, T2Biosystem), and metagenomics-based assays (including SepsiTest, Molzym; iDTECT Dx Blood, PathoQuest; Karius NGS plasma Test, Karius). Performance characteristics, advantages and pitfalls of each method are described, and available data about their impact on patients' clinical outcomes are discussed.The potential of rapid diagnostic tests applied on whole blood for improving the management of patients with bloodstream infection and sepsis is high, both in terms of reducing turnaround times and improving the sensitivity of pathogen and antimicrobial resistance detection. However, overall, there is still a scarcity of data about the real-life performance of such tests, and well-designed studies are awaited for assessing the impact of these emerging technologies on patient outcomes." @default.
• W3205526013 created "2021-10-25" @default.
• W3205526013 creator A5053401736 @default.
• W3205526013 creator A5058005775 @default.
• W3205526013 creator A5082362012 @default.
• W3205526013 date "2022-02-01" @default.
• W3205526013 modified "2023-10-12" @default.
• W3205526013 title "Culture-independent detection systems for bloodstream infection" @default.
• W3205526013 cites W1980538526 @default.
• W3205526013 cites W2073316020 @default.
• W3205526013 cites W2081158506 @default.
• W3205526013 cites W2082173844 @default.
• W3205526013 cites W2110912679 @default.
• W3205526013 cites W2113002556 @default.
• W3205526013 cites W2133663142 @default.
• W3205526013 cites W2152423903 @default.
• W3205526013 cites W2156904141 @default.
• W3205526013 cites W2172786150 @default.
• W3205526013 cites W2185226679 @default.
• W3205526013 cites W2513378575 @default.
• W3205526013 cites W2525326149 @default.
• W3205526013 cites W2562117933 @default.
• W3205526013 cites W2586669928 @default.
• W3205526013 cites W2747229478 @default.
• W3205526013 cites W2792762681 @default.
• W3205526013 cites W2794302591 @default.
• W3205526013 cites W2794656411 @default.
• W3205526013 cites W2794779186 @default.
• W3205526013 cites W2795137478 @default.
• W3205526013 cites W2795138004 @default.
• W3205526013 cites W2803481513 @default.
• W3205526013 cites W2808441502 @default.
• W3205526013 cites W2810975230 @default.
• W3205526013 cites W2811347212 @default.
• W3205526013 cites W2898830086 @default.
• W3205526013 cites W2901531873 @default.
• W3205526013 cites W2911798461 @default.
• W3205526013 cites W2921162090 @default.
• W3205526013 cites W2944692699 @default.
• W3205526013 cites W2945363307 @default.
• W3205526013 cites W2946198733 @default.
• W3205526013 cites W2972530789 @default.
• W3205526013 cites W2974590316 @default.
• W3205526013 cites W2990542233 @default.
• W3205526013 cites W2995432985 @default.
• W3205526013 cites W3000477794 @default.
• W3205526013 cites W3001075967 @default.
• W3205526013 cites W3007916435 @default.
• W3205526013 cites W3021025999 @default.
• W3205526013 cites W3041729755 @default.
• W3205526013 cites W3049985613 @default.
• W3205526013 cites W3087089571 @default.
• W3205526013 cites W3115901482 @default.
• W3205526013 cites W3136626436 @default.
• W3205526013 cites W3154360187 @default.
• W3205526013 cites W4211037082 @default.
• W3205526013 doi "https://doi.org/10.1016/j.cmi.2021.09.039" @default.
• W3205526013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34687856" @default.
• W3205526013 hasPublicationYear "2022" @default.
• W3205526013 type Work @default.
• W3205526013 sameAs 3205526013 @default.
• W3205526013 citedByCount "35" @default.
• W3205526013 countsByYear W32055260132021 @default.
• W3205526013 countsByYear W32055260132022 @default.
• W3205526013 countsByYear W32055260132023 @default.
• W3205526013 crossrefType "journal-article" @default.
• W3205526013 hasAuthorship W3205526013A5053401736 @default.
• W3205526013 hasAuthorship W3205526013A5058005775 @default.
• W3205526013 hasAuthorship W3205526013A5082362012 @default.
• W3205526013 hasConcept C111919701 @default.
• W3205526013 hasConcept C176553487 @default.
• W3205526013 hasConcept C177713679 @default.
• W3205526013 hasConcept C203014093 @default.
• W3205526013 hasConcept C2778384902 @default.
• W3205526013 hasConcept C2779443120 @default.
• W3205526013 hasConcept C2779473907 @default.
• W3205526013 hasConcept C3018946976 @default.
• W3205526013 hasConcept C41008148 @default.
• W3205526013 hasConcept C501593827 @default.
• W3205526013 hasConcept C71924100 @default.
• W3205526013 hasConcept C86803240 @default.
• W3205526013 hasConcept C89423630 @default.
• W3205526013 hasConceptScore W3205526013C111919701 @default.
• W3205526013 hasConceptScore W3205526013C176553487 @default.
• W3205526013 hasConceptScore W3205526013C177713679 @default.
• W3205526013 hasConceptScore W3205526013C203014093 @default.
• W3205526013 hasConceptScore W3205526013C2778384902 @default.
• W3205526013 hasConceptScore W3205526013C2779443120 @default.
• W3205526013 hasConceptScore W3205526013C2779473907 @default.
• W3205526013 hasConceptScore W3205526013C3018946976 @default.
• W3205526013 hasConceptScore W3205526013C41008148 @default.
• W3205526013 hasConceptScore W3205526013C501593827 @default.
• W3205526013 hasConceptScore W3205526013C71924100 @default.
• W3205526013 hasConceptScore W3205526013C86803240 @default.
• W3205526013 hasConceptScore W3205526013C89423630 @default.
• W3205526013 hasIssue "2" @default.
• W3205526013 hasLocation W32055260131 @default.
• W3205526013 hasLocation W32055260132 @default.

• next