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- W3205590315 abstract "This article reviews the basics of drug–receptor interactions: affinity, potency and efficacy. We provide a fresh focus on drug efficacy for current and future therapeutics using opioids as examples. Shifts in drug design have led to some new and noteworthy pharmacology concepts including inverse and biased agonism. In addition, the old concept of selectivity is being reconsidered. The design of novel opioids, for example is moving away from developing highly selective ligands for a single opioid receptor towards drugs targeting multiple opioid receptor sites (i.e." @default.
- W3205590315 created "2021-10-25" @default.
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- W3205590315 date "2022-01-01" @default.
- W3205590315 modified "2023-09-26" @default.
- W3205590315 title "Drug–receptor interactions in anaesthesia" @default.
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- W3205590315 doi "https://doi.org/10.1016/j.bjae.2021.07.009" @default.
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