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- W3205632507 abstract "Psoriasis is a multifactorial immune-mediated disease. The highly effective and eligible treatment for psoriasis is limited, for its specific pathogenesis is incompletely elucidated. Skin microbiota is a research hotspot in the pathogenesis of immune-mediated inflammatory skin diseases nowadays, and it may have significant involvement in the provocation or exacerbation of psoriasis with broadly applicable prospects. It is postulated that skin microbiota alternation may interplay with innate immunity such as antimicrobial peptides and Toll-like receptors to stimulate T-cell populations, resulting in immune cascade responses and ultimately psoriasis. Achieving a thorough understanding of its underlying pathogenesis is crucial. Herein, we discuss the potential immunopathogenesis of psoriasis from the aspect of skin microbiota in an attempt to yield insights for novel therapeutic and preventive modalities for psoriasis." @default.
- W3205632507 created "2021-10-25" @default.
- W3205632507 creator A5003217704 @default.
- W3205632507 creator A5018006068 @default.
- W3205632507 creator A5040123921 @default.
- W3205632507 creator A5049323232 @default.
- W3205632507 creator A5050612841 @default.
- W3205632507 creator A5059871374 @default.
- W3205632507 creator A5085482573 @default.
- W3205632507 date "2021-10-18" @default.
- W3205632507 modified "2023-10-17" @default.
- W3205632507 title "Interplay Between Skin Microbiota Dysbiosis and the Host Immune System in Psoriasis: Potential Pathogenesis" @default.
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