FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3205693895> ?p ?o ?g. }

• W3205693895 endingPage "112152" @default.
• W3205693895 startingPage "112152" @default.
• W3205693895 abstract "The management of contact lens discomfort remains a challenge leading to the increased contact lens dropout rates. Tear protein accumulates on the lens surfaces with different configurations observed are correlated to the lens friction, with the improved comfort experienced by reduced surface friction in the eye. However, protein adsorption is a complex process with the combined protein-protein interactions (PPI) and protein-surface interactions (PSI) involved, which is difficult to explain the complicated tribological behavior in terms of protein structural shifts alone on lens surfaces. On the other hand, the type of solvent-exposed side chains from specific protein conformations on lens surfaces should be more important to the lens friction involved. We aim to investigate the correlation between the structure-related side-chain exposure and corresponding lens friction of adsorbed tear proteins on lens surfaces under varied PPI and PSI. Albumin was the model protein adsorbed onto the conventional lens material. Such as polymethylmethacrylate (PMMA) or the poly-2-hydroxyethyl methacrylate (PHEMA) surfaces applied here. Adsorption was conducted under varying protein solution concentrations to saturate the model surface to change the PPI effects over a wide range. Our results indicate that PPI effects help stabilize protein structures on both surfaces. When PPI is minimized, a distinct correlation was observed between the surface friction and the hydrophobicity of structure-related side-chain exposure of albumin on lens surfaces depending on the different PSI involved. At a fundamental understanding, our results would provide insights for developing new lens materials or the lens care solution designs to reduce the lens discomfort." @default.
• W3205693895 created "2021-10-25" @default.
• W3205693895 creator A5030340580 @default.
• W3205693895 creator A5035884325 @default.
• W3205693895 creator A5067042613 @default.
• W3205693895 creator A5071003960 @default.
• W3205693895 date "2022-01-01" @default.
• W3205693895 modified "2023-10-12" @default.
• W3205693895 title "Correlation between surface friction and the hydrophobicity of structure-related side-chain exposure of albumin on contact lens" @default.
• W3205693895 cites W1036418443 @default.
• W3205693895 cites W1529813175 @default.
• W3205693895 cites W1924131645 @default.
• W3205693895 cites W1966940492 @default.
• W3205693895 cites W1973794796 @default.
• W3205693895 cites W1975259825 @default.
• W3205693895 cites W1978452759 @default.
• W3205693895 cites W1980428120 @default.
• W3205693895 cites W1988840545 @default.
• W3205693895 cites W1993397944 @default.
• W3205693895 cites W1994051469 @default.
• W3205693895 cites W2002995327 @default.
• W3205693895 cites W2003487296 @default.
• W3205693895 cites W2004508840 @default.
• W3205693895 cites W2018929284 @default.
• W3205693895 cites W2023978004 @default.
• W3205693895 cites W2026727321 @default.
• W3205693895 cites W2032689521 @default.
• W3205693895 cites W2045429977 @default.
• W3205693895 cites W2047144051 @default.
• W3205693895 cites W2051584370 @default.
• W3205693895 cites W2055758194 @default.
• W3205693895 cites W2057507361 @default.
• W3205693895 cites W2081036774 @default.
• W3205693895 cites W2081850523 @default.
• W3205693895 cites W2084997955 @default.
• W3205693895 cites W2085026278 @default.
• W3205693895 cites W2094801969 @default.
• W3205693895 cites W2098293383 @default.
• W3205693895 cites W2098835843 @default.
• W3205693895 cites W2099045180 @default.
• W3205693895 cites W2103942482 @default.
• W3205693895 cites W2105098043 @default.
• W3205693895 cites W2110176833 @default.
• W3205693895 cites W2112160995 @default.
• W3205693895 cites W2115411268 @default.
• W3205693895 cites W2139024831 @default.
• W3205693895 cites W2140260269 @default.
• W3205693895 cites W2150724720 @default.
• W3205693895 cites W2153259519 @default.
• W3205693895 cites W2164205436 @default.
• W3205693895 cites W2164519473 @default.
• W3205693895 cites W2168862471 @default.
• W3205693895 cites W2256212438 @default.
• W3205693895 cites W2345870135 @default.
• W3205693895 cites W2401479208 @default.
• W3205693895 cites W2567655809 @default.
• W3205693895 cites W2586329783 @default.
• W3205693895 cites W2587841446 @default.
• W3205693895 cites W2613544357 @default.
• W3205693895 cites W2616874377 @default.
• W3205693895 cites W2696923578 @default.
• W3205693895 cites W2731548879 @default.
• W3205693895 cites W2775075940 @default.
• W3205693895 cites W2790915242 @default.
• W3205693895 cites W289241723 @default.
• W3205693895 cites W2909056211 @default.
• W3205693895 cites W2911681137 @default.
• W3205693895 cites W2923560472 @default.
• W3205693895 cites W2946593644 @default.
• W3205693895 cites W2979378532 @default.
• W3205693895 cites W2980476140 @default.
• W3205693895 cites W3025484814 @default.
• W3205693895 cites W3037116206 @default.
• W3205693895 cites W3045184272 @default.
• W3205693895 cites W3116381253 @default.
• W3205693895 cites W757322968 @default.
• W3205693895 doi "https://doi.org/10.1016/j.colsurfb.2021.112152" @default.
• W3205693895 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34655983" @default.
• W3205693895 hasPublicationYear "2022" @default.
• W3205693895 type Work @default.
• W3205693895 sameAs 3205693895 @default.
• W3205693895 citedByCount "2" @default.
• W3205693895 countsByYear W32056938952022 @default.
• W3205693895 countsByYear W32056938952023 @default.
• W3205693895 crossrefType "journal-article" @default.
• W3205693895 hasAuthorship W3205693895A5030340580 @default.
• W3205693895 hasAuthorship W3205693895A5035884325 @default.
• W3205693895 hasAuthorship W3205693895A5067042613 @default.
• W3205693895 hasAuthorship W3205693895A5071003960 @default.
• W3205693895 hasConcept C120665830 @default.
• W3205693895 hasConcept C121332964 @default.
• W3205693895 hasConcept C12554922 @default.
• W3205693895 hasConcept C127413603 @default.
• W3205693895 hasConcept C150394285 @default.
• W3205693895 hasConcept C15336307 @default.
• W3205693895 hasConcept C159985019 @default.
• W3205693895 hasConcept C178790620 @default.
• W3205693895 hasConcept C185592680 @default.

• next