FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3205699522> ?p ?o ?g. }

• W3205699522 abstract "Porcine epidemic diarrhea virus (PEDV), which classified in the genus Alphacoronavirus, family Coronaviridae, is one of the most important pathogens that cause heavy economic losses in pig industry. Although intensive mutation and recombination analysis of PEDV strains were provided, systematic genome analysis were needed to elucidate the evolution mechanism and codon usage adaptation profiles of the pathogen. Here, a comprehensive investigation was carried out to reveal the systematic evolutionary processes of synonymous codon usage and host-adapted evolution phenotype of PEDV genome. We found a low codon usage bias (CUB) in PEDV genome and that nucleotide compositions, natural selection, mutation pressure and geographical diversity shapes the codon usage patterns of PEDV, with natural selection dominated the overall codon usage bias in PEDV than the others. By using the relative codon deoptimization index (RCDI) and similarity index (SiD) analysis, we observed that genotype II PEDV strains showed the highest level of adaptation phenotype to Sus scrofa than another divergent clade. To the best of our knowledge, this is the first comprehensive report elaborating the codon usage and host adaptation of PEDV. The findings offer an insight into our understanding of factors involved in PEDV evolution, adaptation and fitness toward their hosts." @default.
• W3205699522 created "2021-10-25" @default.
• W3205699522 creator A5010444377 @default.
• W3205699522 creator A5019529071 @default.
• W3205699522 creator A5036560540 @default.
• W3205699522 creator A5049470816 @default.
• W3205699522 creator A5083297415 @default.
• W3205699522 date "2021-10-18" @default.
• W3205699522 modified "2023-09-30" @default.
• W3205699522 title "Study on the Characteristic Codon Usage Pattern in Porcine Epidemic Diarrhea Virus Genomes and Its Host Adaptation Phenotype" @default.
• W3205699522 cites W1926697416 @default.
• W3205699522 cites W1927653981 @default.
• W3205699522 cites W1966622966 @default.
• W3205699522 cites W1966773394 @default.
• W3205699522 cites W1969564692 @default.
• W3205699522 cites W1976462769 @default.
• W3205699522 cites W1977790594 @default.
• W3205699522 cites W1985048046 @default.
• W3205699522 cites W1991049350 @default.
• W3205699522 cites W2000619289 @default.
• W3205699522 cites W2001674944 @default.
• W3205699522 cites W2004146038 @default.
• W3205699522 cites W2019604065 @default.
• W3205699522 cites W2035438291 @default.
• W3205699522 cites W2042157784 @default.
• W3205699522 cites W2043592686 @default.
• W3205699522 cites W2046299964 @default.
• W3205699522 cites W2051043527 @default.
• W3205699522 cites W2055149416 @default.
• W3205699522 cites W2059628904 @default.
• W3205699522 cites W2070163065 @default.
• W3205699522 cites W2072284352 @default.
• W3205699522 cites W2084241014 @default.
• W3205699522 cites W2084387345 @default.
• W3205699522 cites W2086955313 @default.
• W3205699522 cites W2112533943 @default.
• W3205699522 cites W2115973975 @default.
• W3205699522 cites W2118021954 @default.
• W3205699522 cites W2120253101 @default.
• W3205699522 cites W2121646171 @default.
• W3205699522 cites W2127543611 @default.
• W3205699522 cites W2135132843 @default.
• W3205699522 cites W2140211206 @default.
• W3205699522 cites W2145623832 @default.
• W3205699522 cites W2152812151 @default.
• W3205699522 cites W2164393923 @default.
• W3205699522 cites W2243973145 @default.
• W3205699522 cites W2282841281 @default.
• W3205699522 cites W2343777714 @default.
• W3205699522 cites W2467771559 @default.
• W3205699522 cites W2518183482 @default.
• W3205699522 cites W2524169008 @default.
• W3205699522 cites W2530359606 @default.
• W3205699522 cites W2558210648 @default.
• W3205699522 cites W2614081736 @default.
• W3205699522 cites W2625255676 @default.
• W3205699522 cites W2800048358 @default.
• W3205699522 cites W2806155816 @default.
• W3205699522 cites W2898629212 @default.
• W3205699522 cites W2903515313 @default.
• W3205699522 cites W2933062146 @default.
• W3205699522 cites W2951126701 @default.
• W3205699522 cites W2961280538 @default.
• W3205699522 cites W2967192073 @default.
• W3205699522 cites W2973611214 @default.
• W3205699522 cites W2980809007 @default.
• W3205699522 cites W2986073447 @default.
• W3205699522 cites W2996163123 @default.
• W3205699522 cites W2997884959 @default.
• W3205699522 cites W2999425026 @default.
• W3205699522 cites W3005235420 @default.
• W3205699522 cites W3006106077 @default.
• W3205699522 cites W3012485903 @default.
• W3205699522 cites W3033020576 @default.
• W3205699522 cites W3033391459 @default.
• W3205699522 cites W3041275474 @default.
• W3205699522 cites W3087572725 @default.
• W3205699522 cites W3094599108 @default.
• W3205699522 cites W3096206142 @default.
• W3205699522 cites W3107305086 @default.
• W3205699522 cites W3121985566 @default.
• W3205699522 cites W3123766866 @default.
• W3205699522 cites W3127456882 @default.
• W3205699522 cites W3127481044 @default.
• W3205699522 cites W3135415606 @default.
• W3205699522 cites W3138025113 @default.
• W3205699522 cites W3142792029 @default.
• W3205699522 cites W3153719477 @default.
• W3205699522 cites W3156458251 @default.
• W3205699522 cites W3161756555 @default.
• W3205699522 doi "https://doi.org/10.3389/fmicb.2021.738082" @default.
• W3205699522 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8558211" @default.
• W3205699522 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34733253" @default.
• W3205699522 hasPublicationYear "2021" @default.
• W3205699522 type Work @default.
• W3205699522 sameAs 3205699522 @default.
• W3205699522 citedByCount "12" @default.
• W3205699522 countsByYear W32056995222022 @default.
• W3205699522 countsByYear W32056995222023 @default.
• W3205699522 crossrefType "journal-article" @default.

• next