Matches in SemOpenAlex for { <https://semopenalex.org/work/W3205704191> ?p ?o ?g. }
Showing items 1 to 59 of
59
with 100 items per page.
- W3205704191 abstract "ABO blood group incompatibility and HLA sensitization are major barriers that need to be overcome in order to make optimum use of kidneys from living donors possible. We report the first successful ABOincompatible kidney transplant in a 24-year old, highly sensitized (panel reactive antibodies (PRA) 89% kidney retransplantation patient, who lacked any option to get a cadaveric or family donor. However, the patient’s sole HLA-compatible living donor had group A blood incompatible with the recipient’s O blood group. The patient required a pre-conditioning regime that consisted of plasma exchange, rituximab, immunoglobulin, and quadruple immunosuppressive therapy in order to reduce high titers of anti-A isoagglutinins from 1:128 to a safe level of 1:8, for successful transplant. This was performed in coordination with the Renal Transplant Unit of Hospital Clinic de Barcelona (HCB), Spain. Absence of rejection mediated by isoagglutinins shows the potential benefit of a protocol consisting in removing antibodies from the anti-blood group. Two years after transplantation, the kidney function remains stable, with creatinine levels of 1.5 mg%. We conclude that an ABO-incompatible kidney transplant is a viable option for patients whose only donor has blood of an incompatible blood group and for us this represents a hope-inspiring source of organs." @default.
- W3205704191 created "2021-10-25" @default.
- W3205704191 creator A5001097416 @default.
- W3205704191 creator A5004101231 @default.
- W3205704191 creator A5017166254 @default.
- W3205704191 creator A5038633110 @default.
- W3205704191 creator A5040530313 @default.
- W3205704191 creator A5055415519 @default.
- W3205704191 creator A5058462300 @default.
- W3205704191 creator A5067059060 @default.
- W3205704191 date "2017-01-01" @default.
- W3205704191 modified "2023-10-15" @default.
- W3205704191 title "Trasplante renal grupo sanguíneo ABO incompatible: experiencia colaborativa inédita España y Perú" @default.
- W3205704191 hasPublicationYear "2017" @default.
- W3205704191 type Work @default.
- W3205704191 sameAs 3205704191 @default.
- W3205704191 citedByCount "0" @default.
- W3205704191 crossrefType "journal-article" @default.
- W3205704191 hasAuthorship W3205704191A5001097416 @default.
- W3205704191 hasAuthorship W3205704191A5004101231 @default.
- W3205704191 hasAuthorship W3205704191A5017166254 @default.
- W3205704191 hasAuthorship W3205704191A5038633110 @default.
- W3205704191 hasAuthorship W3205704191A5040530313 @default.
- W3205704191 hasAuthorship W3205704191A5055415519 @default.
- W3205704191 hasAuthorship W3205704191A5058462300 @default.
- W3205704191 hasAuthorship W3205704191A5067059060 @default.
- W3205704191 hasConcept C126322002 @default.
- W3205704191 hasConcept C126894567 @default.
- W3205704191 hasConcept C141071460 @default.
- W3205704191 hasConcept C159641895 @default.
- W3205704191 hasConcept C159654299 @default.
- W3205704191 hasConcept C176080213 @default.
- W3205704191 hasConcept C203014093 @default.
- W3205704191 hasConcept C2780091579 @default.
- W3205704191 hasConcept C2780303639 @default.
- W3205704191 hasConcept C2780653079 @default.
- W3205704191 hasConcept C2910652704 @default.
- W3205704191 hasConcept C2911091166 @default.
- W3205704191 hasConcept C71924100 @default.
- W3205704191 hasConceptScore W3205704191C126322002 @default.
- W3205704191 hasConceptScore W3205704191C126894567 @default.
- W3205704191 hasConceptScore W3205704191C141071460 @default.
- W3205704191 hasConceptScore W3205704191C159641895 @default.
- W3205704191 hasConceptScore W3205704191C159654299 @default.
- W3205704191 hasConceptScore W3205704191C176080213 @default.
- W3205704191 hasConceptScore W3205704191C203014093 @default.
- W3205704191 hasConceptScore W3205704191C2780091579 @default.
- W3205704191 hasConceptScore W3205704191C2780303639 @default.
- W3205704191 hasConceptScore W3205704191C2780653079 @default.
- W3205704191 hasConceptScore W3205704191C2910652704 @default.
- W3205704191 hasConceptScore W3205704191C2911091166 @default.
- W3205704191 hasConceptScore W3205704191C71924100 @default.
- W3205704191 hasLocation W32057041911 @default.
- W3205704191 hasOpenAccess W3205704191 @default.
- W3205704191 hasPrimaryLocation W32057041911 @default.
- W3205704191 isParatext "false" @default.
- W3205704191 isRetracted "false" @default.
- W3205704191 magId "3205704191" @default.
- W3205704191 workType "article" @default.