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- W320587905 abstract "The aim of our study was to identify adverse clinic-pathologic factors for survival in patients with re-current endometrial carcinoma. From 1970 to 1992, 722 patients with endometrial carcinoma were treated at our institution. Of these, 98 patients presented loco-regional recurrences and/ or distant metastases, and they form the basis of this report. Patient, clinical and pathologic factors were analysed by univariate and multivariate techniques to identify independent prognostic factors for time to recurrence, local control and survival. With a median follow-up post-recurrence of 11.8 months, the 3-year local control and overall survival rate was 34% and 45%, respectively. Pathologic stage II–III at presentation (p=0.024) and post-ope-rative radiation therapy at initial treatment (p=0.005) were adverse prognostic factors for local con-trol post-recurrence. Histologic subtype papillary-serous, clear cell carcinoma and the lack of local control at relapse were the main adverse prognostic factors for overall survival in all group and in the subgroup of patients with only loco-regional recurrence, respectively. Histologic type is the main prognostic factor for overall survival in recurrent endometrial carcinoma. Only patients who achieve local control after recurrence hope to become long-term survivors." @default.
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- W320587905 date "2002-11-01" @default.
- W320587905 modified "2023-09-27" @default.
- W320587905 title "Prognostic factors in recurrent endometrial carcinoma" @default.
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- W320587905 doi "https://doi.org/10.1007/bf02719120" @default.
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