Matches in SemOpenAlex for { <https://semopenalex.org/work/W3205888794> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W3205888794 abstract "Sarcosine, also known as N-methyl glycine, is a natural amino acid that is an intermediate and by product in glycine synthesis and degradation. Recently found in many peptides, sarcosine has been researched as a newly accepted prostate cancer marker. The increased concentration of sarcosine in blood serum and the urine showed that malignancy of measured prostate cancer cells is active.In this article, we aimed to design a potentiometric biosensor for detection of sarcosine with a low detection limit, high selectivity, short response time, wide linear range, and satisfactory long-term stability.In this article, we developed a new Graphene oxide (GFOX) photosensitive cross-linker based potentiometric biosensor based on the AmiNoAcid (monomer) Decorated and Light Underpinning Conjugation Approach (ANADOLUCA) method. The functional groups determined using Raman, FT-IR, XPS analyzes, and surface characterization, the morphology of synthesized GFOX photosensitive cross-linker were determined by TEM and AFM studies. Then, the performance of the GFOX based potentiometric biosensor has been evaluated.When the usage of the developed GFOX doped potentiometric biosensor against sarcosine determination, it was found that 10-4 mM sarcosine was determined in 60 seconds in the solution. In addition, the detection limit of the GFOX doped potentiometric biosensor was found to be 9.45x10-7 mM, and the linear potentiometric biosensor was found to be in the concentration range of 10-1 to 10-5 mM. The selectivity studies of the developed potentiometric biosensor were investigated using glycine solutions, and it was determined that GFOX doped potentiometric biosensor was more selective against sarcosine. Besides this, a reusability test using 10-3 mM sarcosine solution showed that reproducible studies were performed without the loss of potential of designed potentiometric biosensor and no loss of sensitivity.After applying the framework, we get a new potentiometric biosensor for sarcosine determination. GFOX photosensitive cross-linker was used in designing potentiometric biosensors, and this increased the stability and efficiency of the biosensor. Therefore, the developed potentiometric biosensor for sarcosine determination could be easily used for the early diagnosis of prostate cancer." @default.
- W3205888794 created "2021-10-25" @default.
- W3205888794 creator A5000599676 @default.
- W3205888794 creator A5003382732 @default.
- W3205888794 creator A5038054919 @default.
- W3205888794 creator A5074480604 @default.
- W3205888794 date "2021-10-08" @default.
- W3205888794 modified "2023-10-16" @default.
- W3205888794 title "Graphenoxide Cross-Linker Based Potentiometric Biosensor Design For Sarcosine Determination" @default.
- W3205888794 doi "https://doi.org/10.2174/0929866528666211008160111" @default.
- W3205888794 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34629039" @default.
- W3205888794 hasPublicationYear "2021" @default.
- W3205888794 type Work @default.
- W3205888794 sameAs 3205888794 @default.
- W3205888794 citedByCount "0" @default.
- W3205888794 crossrefType "journal-article" @default.
- W3205888794 hasAuthorship W3205888794A5000599676 @default.
- W3205888794 hasAuthorship W3205888794A5003382732 @default.
- W3205888794 hasAuthorship W3205888794A5038054919 @default.
- W3205888794 hasAuthorship W3205888794A5074480604 @default.
- W3205888794 hasConcept C118792377 @default.
- W3205888794 hasConcept C119128265 @default.
- W3205888794 hasConcept C124614425 @default.
- W3205888794 hasConcept C13965031 @default.
- W3205888794 hasConcept C147789679 @default.
- W3205888794 hasConcept C160756335 @default.
- W3205888794 hasConcept C161790260 @default.
- W3205888794 hasConcept C17525397 @default.
- W3205888794 hasConcept C185592680 @default.
- W3205888794 hasConcept C195767000 @default.
- W3205888794 hasConcept C2777756961 @default.
- W3205888794 hasConcept C2779943223 @default.
- W3205888794 hasConcept C43617362 @default.
- W3205888794 hasConcept C515207424 @default.
- W3205888794 hasConcept C55493867 @default.
- W3205888794 hasConceptScore W3205888794C118792377 @default.
- W3205888794 hasConceptScore W3205888794C119128265 @default.
- W3205888794 hasConceptScore W3205888794C124614425 @default.
- W3205888794 hasConceptScore W3205888794C13965031 @default.
- W3205888794 hasConceptScore W3205888794C147789679 @default.
- W3205888794 hasConceptScore W3205888794C160756335 @default.
- W3205888794 hasConceptScore W3205888794C161790260 @default.
- W3205888794 hasConceptScore W3205888794C17525397 @default.
- W3205888794 hasConceptScore W3205888794C185592680 @default.
- W3205888794 hasConceptScore W3205888794C195767000 @default.
- W3205888794 hasConceptScore W3205888794C2777756961 @default.
- W3205888794 hasConceptScore W3205888794C2779943223 @default.
- W3205888794 hasConceptScore W3205888794C43617362 @default.
- W3205888794 hasConceptScore W3205888794C515207424 @default.
- W3205888794 hasConceptScore W3205888794C55493867 @default.
- W3205888794 hasLocation W32058887941 @default.
- W3205888794 hasLocation W32058887942 @default.
- W3205888794 hasOpenAccess W3205888794 @default.
- W3205888794 hasPrimaryLocation W32058887941 @default.
- W3205888794 hasRelatedWork W1837235693 @default.
- W3205888794 hasRelatedWork W1964620449 @default.
- W3205888794 hasRelatedWork W2048277678 @default.
- W3205888794 hasRelatedWork W2082093578 @default.
- W3205888794 hasRelatedWork W2093180229 @default.
- W3205888794 hasRelatedWork W2150755762 @default.
- W3205888794 hasRelatedWork W2165755634 @default.
- W3205888794 hasRelatedWork W3196237169 @default.
- W3205888794 hasRelatedWork W3205888794 @default.
- W3205888794 hasRelatedWork W3217154234 @default.
- W3205888794 hasVolume "28" @default.
- W3205888794 isParatext "false" @default.
- W3205888794 isRetracted "false" @default.
- W3205888794 magId "3205888794" @default.
- W3205888794 workType "article" @default.