Matches in SemOpenAlex for { <https://semopenalex.org/work/W3205925800> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W3205925800 abstract "Objective: To describe the trends in the incidence rate of HIV VL rebound and assess the factors associated with the incidence rate of HIV VL rebound among the persons receiving ART in Malawi between 2011 and 2020. Methods: We analyzed routinely collected patient-level HIV VL data extracted from the Malawi Laboratory Management Information System (LIMS). We fitted a multivariable Cox regression model of having HIV VL rebound (>1000 copies/mL) using a forward step-wise selection method, with age and sex entered as a priori variables. We presented both crude and adjusted hazard ratios (aHR) of HIV VL rebound for the various independent variables. Statistical significance was set at P<0.05. Results: We evaluated 230,465 adults and children receiving ART and having at least one viral load test between 2011 and 2020. The median time between ART initiation and having a VL sample was 55 months (interquartile range: 25-92). The aHR for having HIV VL rebound were: 0.79 for females (95%CI:0.77-0.80, P<0.001) compared to males, 0.95 (95%CI: 0.94-0.98, P<0.001) for patients from rural compared to urban areas and 0.57 (95%CI:0.56-0.58, P<0.001) for routine compared to targeted VL tests. There was a decreasing trend in the aHR of patients having HIV VL rebound with increasing age. Conclusion: This is the first national analysis of Malawi HIV VL data from LIMS. Our findings show the need to take into account the geographic and demographic characteristics of the patients in order to persistently suppress HIV VL and consequently achieve 95% HIV VL suppression by 2030." @default.
- W3205925800 created "2021-10-25" @default.
- W3205925800 creator A5008028828 @default.
- W3205925800 creator A5010853610 @default.
- W3205925800 creator A5011657274 @default.
- W3205925800 creator A5020104507 @default.
- W3205925800 creator A5027960712 @default.
- W3205925800 creator A5044658844 @default.
- W3205925800 creator A5090507080 @default.
- W3205925800 date "2021-10-10" @default.
- W3205925800 modified "2023-10-16" @default.
- W3205925800 title "Factors associated with the incidence rate of HIV viral rebound among children and adults receiving antiretroviral therapy in Malawi using the Laboratory Management information System: 2011-2020" @default.
- W3205925800 cites W2031594440 @default.
- W3205925800 cites W2396048690 @default.
- W3205925800 cites W2610466423 @default.
- W3205925800 cites W2784132083 @default.
- W3205925800 cites W2947035147 @default.
- W3205925800 cites W2947921979 @default.
- W3205925800 cites W2969424706 @default.
- W3205925800 cites W2980086361 @default.
- W3205925800 cites W3007259777 @default.
- W3205925800 cites W3019421801 @default.
- W3205925800 cites W3042182878 @default.
- W3205925800 cites W3046662146 @default.
- W3205925800 cites W3107047527 @default.
- W3205925800 cites W3124418414 @default.
- W3205925800 cites W314975799 @default.
- W3205925800 doi "https://doi.org/10.1101/2021.10.07.21264672" @default.
- W3205925800 hasPublicationYear "2021" @default.
- W3205925800 type Work @default.
- W3205925800 sameAs 3205925800 @default.
- W3205925800 citedByCount "0" @default.
- W3205925800 crossrefType "posted-content" @default.
- W3205925800 hasAuthorship W3205925800A5008028828 @default.
- W3205925800 hasAuthorship W3205925800A5010853610 @default.
- W3205925800 hasAuthorship W3205925800A5011657274 @default.
- W3205925800 hasAuthorship W3205925800A5020104507 @default.
- W3205925800 hasAuthorship W3205925800A5027960712 @default.
- W3205925800 hasAuthorship W3205925800A5044658844 @default.
- W3205925800 hasAuthorship W3205925800A5090507080 @default.
- W3205925800 hasBestOaLocation W32059258001 @default.
- W3205925800 hasConcept C119060515 @default.
- W3205925800 hasConcept C120665830 @default.
- W3205925800 hasConcept C121332964 @default.
- W3205925800 hasConcept C126322002 @default.
- W3205925800 hasConcept C142462285 @default.
- W3205925800 hasConcept C144024400 @default.
- W3205925800 hasConcept C149923435 @default.
- W3205925800 hasConcept C203014093 @default.
- W3205925800 hasConcept C207103383 @default.
- W3205925800 hasConcept C2993143319 @default.
- W3205925800 hasConcept C3013748606 @default.
- W3205925800 hasConcept C44249647 @default.
- W3205925800 hasConcept C50382708 @default.
- W3205925800 hasConcept C61511704 @default.
- W3205925800 hasConcept C65409693 @default.
- W3205925800 hasConcept C71924100 @default.
- W3205925800 hasConceptScore W3205925800C119060515 @default.
- W3205925800 hasConceptScore W3205925800C120665830 @default.
- W3205925800 hasConceptScore W3205925800C121332964 @default.
- W3205925800 hasConceptScore W3205925800C126322002 @default.
- W3205925800 hasConceptScore W3205925800C142462285 @default.
- W3205925800 hasConceptScore W3205925800C144024400 @default.
- W3205925800 hasConceptScore W3205925800C149923435 @default.
- W3205925800 hasConceptScore W3205925800C203014093 @default.
- W3205925800 hasConceptScore W3205925800C207103383 @default.
- W3205925800 hasConceptScore W3205925800C2993143319 @default.
- W3205925800 hasConceptScore W3205925800C3013748606 @default.
- W3205925800 hasConceptScore W3205925800C44249647 @default.
- W3205925800 hasConceptScore W3205925800C50382708 @default.
- W3205925800 hasConceptScore W3205925800C61511704 @default.
- W3205925800 hasConceptScore W3205925800C65409693 @default.
- W3205925800 hasConceptScore W3205925800C71924100 @default.
- W3205925800 hasLocation W32059258001 @default.
- W3205925800 hasOpenAccess W3205925800 @default.
- W3205925800 hasPrimaryLocation W32059258001 @default.
- W3205925800 hasRelatedWork W2005101102 @default.
- W3205925800 hasRelatedWork W2748983855 @default.
- W3205925800 hasRelatedWork W2905107317 @default.
- W3205925800 hasRelatedWork W2990356869 @default.
- W3205925800 hasRelatedWork W4220894199 @default.
- W3205925800 hasRelatedWork W4221101608 @default.
- W3205925800 hasRelatedWork W4280501115 @default.
- W3205925800 hasRelatedWork W4298619699 @default.
- W3205925800 hasRelatedWork W4302304636 @default.
- W3205925800 hasRelatedWork W4321333614 @default.
- W3205925800 isParatext "false" @default.
- W3205925800 isRetracted "false" @default.
- W3205925800 magId "3205925800" @default.
- W3205925800 workType "article" @default.