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• W3205933095 abstract "Sugemalimab is a full-length, fully human PD-L1 targeted immunoglobin G4 (IgG4, s228p) mAb. GEMSTONE-302 is a randomized, double-blind, phase 3 study to evaluate the efficacy and safety of sugemalimab or placebo in combination with chemotherapy as first-line treatment in metastatic squamous (sq) or non-squamous (nsq) NSCLC. The PFS interim analysis data as of 08 June 2020 showed that sugemalimab plus chemotherapy demonstrated a clinically meaningful and statistically significant prolongation of PFS with a well-tolerated safety profile in metastatic NSCLC patients irrespective of tumor pathology and PD-L1 expression." @default.
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• W3205933095 date "2021-10-01" @default.
• W3205933095 modified "2023-10-17" @default.
• W3205933095 title "MA13.07 GEMSTONE-302: A Phase 3 Study of Platinum-Based Chemotherapy with Placebo or Sugemalimab, a PD-L1 mAb, for metastatic NSCLC" @default.
• W3205933095 doi "https://doi.org/10.1016/j.jtho.2021.08.180" @default.
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