Matches in SemOpenAlex for { <https://semopenalex.org/work/W3205933965> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W3205933965 endingPage "14" @default.
- W3205933965 startingPage "14" @default.
- W3205933965 abstract "Identifying the most sensitive functional measure in intermediate age-related macular degeneration (iAMD) could help select an appropriate test for monitoring disease progression and evaluating the efficacy of novel interventions for the early stages of AMD. The purpose of the study was to determine which commonly used visual function test is the most discriminatory when comparing individuals with iAMD to normal participants.In this prospective observational study, iAMD cases and healthy controls underwent visual function testing (best corrected visual acuity (BCVA), low luminance visual acuity (LLVA), mesopic microperimetry, dark adaptation, and scotopic perimetry following photobleach), clinical eye examination, and multimodal retinal imaging in a single study visit. The data of each functional parameter were converted into z-score so that all the parameters had a common scale to allow a direct comparison between different functional parameters.Forty-eight subjects (23 normal control, 25 iAMD) participated. Although all five parameters showed a significant reduction in function in iAMD eyes compared to controls (P ≤ 0.003), the rod intercept time (RIT) detected the greatest reduction in function followed by the scotopic sensitivity, mesopic sensitivity, BCVA, and LLVA, with the absolute mean z-score of 4.5, 2.2, 1.0, 1.0, and 1.2, respectively.Among the five visual function parameters commonly used, RIT is the most discriminatory functional parameter in the early stages of AMD.The RIT could be considered for assessing visual function and evaluating efficacy of novel interventions aimed at improving retinal function in eyes with early stages of AMD." @default.
- W3205933965 created "2021-10-25" @default.
- W3205933965 creator A5018839865 @default.
- W3205933965 creator A5051997081 @default.
- W3205933965 creator A5082807077 @default.
- W3205933965 date "2021-10-12" @default.
- W3205933965 modified "2023-10-16" @default.
- W3205933965 title "Comparison of Visual Function Tests in Intermediate Age-Related Macular Degeneration" @default.
- W3205933965 cites W1853674701 @default.
- W3205933965 cites W1914217850 @default.
- W3205933965 cites W1961778296 @default.
- W3205933965 cites W1972642682 @default.
- W3205933965 cites W1987648803 @default.
- W3205933965 cites W2013673496 @default.
- W3205933965 cites W2020353417 @default.
- W3205933965 cites W2024979469 @default.
- W3205933965 cites W2038595184 @default.
- W3205933965 cites W2040407827 @default.
- W3205933965 cites W2051842630 @default.
- W3205933965 cites W2054508286 @default.
- W3205933965 cites W2065735797 @default.
- W3205933965 cites W2067364714 @default.
- W3205933965 cites W2084366818 @default.
- W3205933965 cites W2089945049 @default.
- W3205933965 cites W2104516799 @default.
- W3205933965 cites W2144305444 @default.
- W3205933965 cites W2184824787 @default.
- W3205933965 cites W2329780587 @default.
- W3205933965 cites W2419255724 @default.
- W3205933965 cites W2535783572 @default.
- W3205933965 cites W2766820003 @default.
- W3205933965 cites W2885918621 @default.
- W3205933965 cites W2886512628 @default.
- W3205933965 cites W2886969976 @default.
- W3205933965 cites W2894389495 @default.
- W3205933965 cites W2938857728 @default.
- W3205933965 cites W2978000171 @default.
- W3205933965 cites W2992549978 @default.
- W3205933965 cites W3014059603 @default.
- W3205933965 doi "https://doi.org/10.1167/tvst.10.12.14" @default.
- W3205933965 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8525848" @default.
- W3205933965 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34636906" @default.
- W3205933965 hasPublicationYear "2021" @default.
- W3205933965 type Work @default.
- W3205933965 sameAs 3205933965 @default.
- W3205933965 citedByCount "5" @default.
- W3205933965 countsByYear W32059339652022 @default.
- W3205933965 countsByYear W32059339652023 @default.
- W3205933965 crossrefType "journal-article" @default.
- W3205933965 hasAuthorship W3205933965A5018839865 @default.
- W3205933965 hasAuthorship W3205933965A5051997081 @default.
- W3205933965 hasAuthorship W3205933965A5082807077 @default.
- W3205933965 hasBestOaLocation W32059339651 @default.
- W3205933965 hasConcept C118487528 @default.
- W3205933965 hasConcept C119767625 @default.
- W3205933965 hasConcept C2776403814 @default.
- W3205933965 hasConcept C2778257484 @default.
- W3205933965 hasConcept C2779100554 @default.
- W3205933965 hasConcept C2780827179 @default.
- W3205933965 hasConcept C54497739 @default.
- W3205933965 hasConcept C71924100 @default.
- W3205933965 hasConcept C7243750 @default.
- W3205933965 hasConcept C90171120 @default.
- W3205933965 hasConceptScore W3205933965C118487528 @default.
- W3205933965 hasConceptScore W3205933965C119767625 @default.
- W3205933965 hasConceptScore W3205933965C2776403814 @default.
- W3205933965 hasConceptScore W3205933965C2778257484 @default.
- W3205933965 hasConceptScore W3205933965C2779100554 @default.
- W3205933965 hasConceptScore W3205933965C2780827179 @default.
- W3205933965 hasConceptScore W3205933965C54497739 @default.
- W3205933965 hasConceptScore W3205933965C71924100 @default.
- W3205933965 hasConceptScore W3205933965C7243750 @default.
- W3205933965 hasConceptScore W3205933965C90171120 @default.
- W3205933965 hasIssue "12" @default.
- W3205933965 hasLocation W32059339651 @default.
- W3205933965 hasLocation W32059339652 @default.
- W3205933965 hasLocation W32059339653 @default.
- W3205933965 hasLocation W32059339654 @default.
- W3205933965 hasLocation W32059339655 @default.
- W3205933965 hasOpenAccess W3205933965 @default.
- W3205933965 hasPrimaryLocation W32059339651 @default.
- W3205933965 hasRelatedWork W2001002914 @default.
- W3205933965 hasRelatedWork W2013771446 @default.
- W3205933965 hasRelatedWork W2036214396 @default.
- W3205933965 hasRelatedWork W2088148914 @default.
- W3205933965 hasRelatedWork W2346856078 @default.
- W3205933965 hasRelatedWork W2788641335 @default.
- W3205933965 hasRelatedWork W2790585032 @default.
- W3205933965 hasRelatedWork W3205909906 @default.
- W3205933965 hasRelatedWork W3205933965 @default.
- W3205933965 hasRelatedWork W4206294218 @default.
- W3205933965 hasVolume "10" @default.
- W3205933965 isParatext "false" @default.
- W3205933965 isRetracted "false" @default.
- W3205933965 magId "3205933965" @default.
- W3205933965 workType "article" @default.