FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3205938962> ?p ?o ?g. }

• W3205938962 endingPage "115" @default.
• W3205938962 startingPage "106" @default.
• W3205938962 abstract "Hyperuricemia is related to an increased risk of cardiovascular events from a meta-analysis and antihyperuricemia agents may influence to cardiac function. We evaluated the effect of febuxostat on echocardiographic parameters of diastolic function in patients with asymptomatic hyperuricemia as a prespecified endpoint in the subanalysis of the PRIZE study. Patients in the PRIZE study were assigned randomly to either add-on febuxostat treatment group or control group with only appropriate lifestyle modification. Of the 514 patients in the overall study, 65 patients (31 in the febuxostat group and 34 in the control group) who had complete follow-up echocardiographic data of the ratio of peak early diastolic transmitral flow velocity (E) to peak early diastolic mitral annular velocity (e') at baseline and after 12 and 24 months were included. The primary endpoint was a comparison of the changes in the E/e' between the two groups from baseline to 24 months. Interestingly, e' was slightly decreased in the control group compared with in the febuxostat group (treatment p = 0.068, time, p = 0.337, treatment × Time, p = 0.217). As a result, there were significant increases in E/e' (treatment p = 0.045, time, p = 0.177, treatment × time, p = 0.137) after 24 months in the control group compared with the febuxostat group. There was no significant difference in the serum levels of N-terminal-pro brain natriuretic peptide and high-sensitive troponin I between the two groups during the study period. In conclusions, additional febuxostat treatment in patients with asymptomatic hyperuricemia for 24 months might have a potential of preventable effects on the impaired diastolic dysfunction." @default.
• W3205938962 created "2021-10-25" @default.
• W3205938962 creator A5000520468 @default.
• W3205938962 creator A5000880725 @default.
• W3205938962 creator A5000985642 @default.
• W3205938962 creator A5001338655 @default.
• W3205938962 creator A5003383388 @default.
• W3205938962 creator A5003512436 @default.
• W3205938962 creator A5005515052 @default.
• W3205938962 creator A5005692060 @default.
• W3205938962 creator A5006441304 @default.
• W3205938962 creator A5007368993 @default.
• W3205938962 creator A5007500829 @default.
• W3205938962 creator A5009283470 @default.
• W3205938962 creator A5009871378 @default.
• W3205938962 creator A5010172641 @default.
• W3205938962 creator A5010491253 @default.
• W3205938962 creator A5011143155 @default.
• W3205938962 creator A5011399496 @default.
• W3205938962 creator A5011411876 @default.
• W3205938962 creator A5011565594 @default.
• W3205938962 creator A5012904173 @default.
• W3205938962 creator A5013515522 @default.
• W3205938962 creator A5013792829 @default.
• W3205938962 creator A5014355327 @default.
• W3205938962 creator A5014721024 @default.
• W3205938962 creator A5015215361 @default.
• W3205938962 creator A5015926039 @default.
• W3205938962 creator A5017863780 @default.
• W3205938962 creator A5017895194 @default.
• W3205938962 creator A5017900980 @default.
• W3205938962 creator A5019147041 @default.
• W3205938962 creator A5019445952 @default.
• W3205938962 creator A5019753658 @default.
• W3205938962 creator A5020050750 @default.
• W3205938962 creator A5020632152 @default.
• W3205938962 creator A5020851910 @default.
• W3205938962 creator A5021036967 @default.
• W3205938962 creator A5021523855 @default.
• W3205938962 creator A5021640908 @default.
• W3205938962 creator A5023065104 @default.
• W3205938962 creator A5023153057 @default.
• W3205938962 creator A5023436298 @default.
• W3205938962 creator A5023708695 @default.
• W3205938962 creator A5023823880 @default.
• W3205938962 creator A5024098161 @default.
• W3205938962 creator A5025140721 @default.
• W3205938962 creator A5026510958 @default.
• W3205938962 creator A5027412987 @default.
• W3205938962 creator A5028613947 @default.
• W3205938962 creator A5029150930 @default.
• W3205938962 creator A5030076874 @default.
• W3205938962 creator A5031290868 @default.
• W3205938962 creator A5032253923 @default.
• W3205938962 creator A5032279856 @default.
• W3205938962 creator A5032630701 @default.
• W3205938962 creator A5032754709 @default.
• W3205938962 creator A5032825535 @default.
• W3205938962 creator A5034003717 @default.
• W3205938962 creator A5034179596 @default.
• W3205938962 creator A5034361551 @default.
• W3205938962 creator A5034421778 @default.
• W3205938962 creator A5034996902 @default.
• W3205938962 creator A5035115653 @default.
• W3205938962 creator A5035444754 @default.
• W3205938962 creator A5036582307 @default.
• W3205938962 creator A5037246488 @default.
• W3205938962 creator A5037302816 @default.
• W3205938962 creator A5037659067 @default.
• W3205938962 creator A5038766114 @default.
• W3205938962 creator A5038853771 @default.
• W3205938962 creator A5039071592 @default.
• W3205938962 creator A5039264462 @default.
• W3205938962 creator A5040810570 @default.
• W3205938962 creator A5040898489 @default.
• W3205938962 creator A5041954489 @default.
• W3205938962 creator A5042807633 @default.
• W3205938962 creator A5042899064 @default.
• W3205938962 creator A5043550992 @default.
• W3205938962 creator A5043895658 @default.
• W3205938962 creator A5043980883 @default.
• W3205938962 creator A5044442302 @default.
• W3205938962 creator A5044900516 @default.
• W3205938962 creator A5045998401 @default.
• W3205938962 creator A5046968982 @default.
• W3205938962 creator A5047106328 @default.
• W3205938962 creator A5047182580 @default.
• W3205938962 creator A5047525722 @default.
• W3205938962 creator A5047822588 @default.
• W3205938962 creator A5049261350 @default.
• W3205938962 creator A5051128951 @default.
• W3205938962 creator A5051177836 @default.
• W3205938962 creator A5051332263 @default.
• W3205938962 creator A5051668529 @default.
• W3205938962 creator A5052199230 @default.
• W3205938962 creator A5052401062 @default.
• W3205938962 creator A5052966356 @default.
• W3205938962 creator A5053786396 @default.

• next