Matches in SemOpenAlex for { <https://semopenalex.org/work/W3205954858> ?p ?o ?g. }
- W3205954858 endingPage "14289" @default.
- W3205954858 startingPage "14250" @default.
- W3205954858 abstract "A Lewis base catalyzed, enantioselective sulfenocyclization of alkenes to afford [6,6]spiroketals has been developed. The method uses a chiral Lewis base catalyst with an electrophilic sulfur source to generate enantioenriched thiiranium ion with alkenes. Upon formation, the thiiranium ion is subsequently captured in a cascade-type reaction, wherein a ketone oxygen serves as the nucleophile to open the thiiranium ion and an alcohol provides the secondary cyclization to form biorelevant spiroketals. A variety of electron-rich and electron-neutral E-substituted styrenes form the desired spiroketals in good yields with excellent enantio- and diastereoselectivities. Alkyl-substituted and terminal alkenes participate in the cascade reaction, but with a limited scope compared to the styrenyl substrates. This method allows for rapid formation of highly substituted spiroketals in good yield and excellent enantioselectivity." @default.
- W3205954858 created "2021-10-25" @default.
- W3205954858 creator A5003311390 @default.
- W3205954858 creator A5060673018 @default.
- W3205954858 date "2021-10-21" @default.
- W3205954858 modified "2023-10-14" @default.
- W3205954858 title "Lewis Base Catalyzed, Sulfenium Ion Initiated Enantioselective, Spiroketalization Cascade" @default.
- W3205954858 cites W1599414696 @default.
- W3205954858 cites W1973847774 @default.
- W3205954858 cites W1975339286 @default.
- W3205954858 cites W1986979662 @default.
- W3205954858 cites W1990284598 @default.
- W3205954858 cites W2002790099 @default.
- W3205954858 cites W2006553695 @default.
- W3205954858 cites W2010681029 @default.
- W3205954858 cites W2014417260 @default.
- W3205954858 cites W2014588562 @default.
- W3205954858 cites W2014923099 @default.
- W3205954858 cites W2025590935 @default.
- W3205954858 cites W2035225225 @default.
- W3205954858 cites W2042815698 @default.
- W3205954858 cites W2045596606 @default.
- W3205954858 cites W2059995190 @default.
- W3205954858 cites W2067244774 @default.
- W3205954858 cites W2067718414 @default.
- W3205954858 cites W2069518362 @default.
- W3205954858 cites W2072678984 @default.
- W3205954858 cites W2076612332 @default.
- W3205954858 cites W2079919058 @default.
- W3205954858 cites W2079940753 @default.
- W3205954858 cites W2081607151 @default.
- W3205954858 cites W2091684674 @default.
- W3205954858 cites W2096333189 @default.
- W3205954858 cites W2104929187 @default.
- W3205954858 cites W2121424262 @default.
- W3205954858 cites W2123773613 @default.
- W3205954858 cites W2147698729 @default.
- W3205954858 cites W2166724423 @default.
- W3205954858 cites W2198371282 @default.
- W3205954858 cites W2212093064 @default.
- W3205954858 cites W2282906621 @default.
- W3205954858 cites W2296043566 @default.
- W3205954858 cites W2312847412 @default.
- W3205954858 cites W2321869435 @default.
- W3205954858 cites W2327690129 @default.
- W3205954858 cites W2415605090 @default.
- W3205954858 cites W2429142312 @default.
- W3205954858 cites W2470659897 @default.
- W3205954858 cites W2514357450 @default.
- W3205954858 cites W2551248583 @default.
- W3205954858 cites W2555265993 @default.
- W3205954858 cites W2591782645 @default.
- W3205954858 cites W2594393026 @default.
- W3205954858 cites W2594460241 @default.
- W3205954858 cites W2597607479 @default.
- W3205954858 cites W2622739454 @default.
- W3205954858 cites W2739439285 @default.
- W3205954858 cites W2749799098 @default.
- W3205954858 cites W2784472396 @default.
- W3205954858 cites W2792911938 @default.
- W3205954858 cites W2800881377 @default.
- W3205954858 cites W2804576797 @default.
- W3205954858 cites W2886680295 @default.
- W3205954858 cites W2889245713 @default.
- W3205954858 cites W2949705239 @default.
- W3205954858 cites W2950638221 @default.
- W3205954858 cites W2951233993 @default.
- W3205954858 cites W2951278590 @default.
- W3205954858 cites W2962471083 @default.
- W3205954858 cites W2997052377 @default.
- W3205954858 cites W3005520447 @default.
- W3205954858 cites W3029450165 @default.
- W3205954858 cites W3110812187 @default.
- W3205954858 cites W607406955 @default.
- W3205954858 doi "https://doi.org/10.1021/acs.joc.1c02271" @default.
- W3205954858 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34672623" @default.
- W3205954858 hasPublicationYear "2021" @default.
- W3205954858 type Work @default.
- W3205954858 sameAs 3205954858 @default.
- W3205954858 citedByCount "11" @default.
- W3205954858 countsByYear W32059548582022 @default.
- W3205954858 countsByYear W32059548582023 @default.
- W3205954858 crossrefType "journal-article" @default.
- W3205954858 hasAuthorship W3205954858A5003311390 @default.
- W3205954858 hasAuthorship W3205954858A5060673018 @default.
- W3205954858 hasBestOaLocation W32059548582 @default.
- W3205954858 hasConcept C108204754 @default.
- W3205954858 hasConcept C134121241 @default.
- W3205954858 hasConcept C146686406 @default.
- W3205954858 hasConcept C161790260 @default.
- W3205954858 hasConcept C163638829 @default.
- W3205954858 hasConcept C178790620 @default.
- W3205954858 hasConcept C178907741 @default.
- W3205954858 hasConcept C185592680 @default.
- W3205954858 hasConcept C191897082 @default.
- W3205954858 hasConcept C192562407 @default.
- W3205954858 hasConcept C21951064 @default.
- W3205954858 hasConcept C2777738585 @default.