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- W3205969990 abstract "Various nanoparticles are attracting attention due to their potential biomedical applications, particularly as vaccines and immunoregulatory materials. In recent years, due to climate and environmental changes, inoculation against various infectious diseases has become increasingly important. When purified proteins or peptides are used as an antigen for inoculation, the effectiveness of the vaccination is often insufficient. To strengthen the immunogenicity of antigens, artificial particles have been used as immune-stimulating adjuvants. As methods for the synthesis of nanoparticles of various materials with the precisely controlled size, shape, assembly and surface charge have been developed, the number of reports on the application of nanoparticles to vaccines has increased. In this chapter, these various applications, including our research results gold nonoparticles, are reviewed in terms of cellular uptake and immune response." @default.
- W3205969990 created "2021-10-25" @default.
- W3205969990 creator A5001611564 @default.
- W3205969990 date "2021-01-01" @default.
- W3205969990 modified "2023-10-16" @default.
- W3205969990 title "Development of Nanoparticles as a Vaccine Platform" @default.
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- W3205969990 doi "https://doi.org/10.1007/978-3-030-78338-9_11" @default.
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