FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3206096472> ?p ?o ?g. }

• W3206096472 endingPage "1177" @default.
• W3206096472 startingPage "1169" @default.
• W3206096472 abstract "Carboxymethyl chitosan (CMCS)-based complex coacervate has attracted much attention in drug oral delivery due to its pH-responsive property. As a unique ampholyte polymer, the self-coacervation of CMCS has great research potential. In this work, CMCS self-coacervates were prepared by adjusting the pH of the CMCS aqueous solution close to its isoelectric point. The Fourier-transformed infrared spectroscopy (FTIR) results revealed that electrostatic interactions, hydrogen bonding, and hydrophobic interactions were involved in the self-coacervation of CMCS. The obtained self-coacervates presented a dense surface structure, and were stable at a wide pH range of 3.0-6.0, and gradually dissolved under basic conditions. Although self-coacervation decreased the crystallinity and thermal stability of CMCS, the obtained coacervates showed excellent pH-responsive properties and ionic strength stability. We also investigated its potential in lactoferrin (LF) encapsulation and oral delivery. The CMCS self-coacervates exhibited a high encapsulation efficiency (EE) of 94.79 ± 0.49% and loading capacity (LC) of 26.29 ± 0.52% when the addition amount of LF was 2 mg. The simulated gastric digestion results demonstrated that CMCS self-coacervates could protect more than 80% of LF from hydrolysis and maintain the bioactivities of LF. Accordingly, the self-coacervation of CMCS could be used as a pH-responsive encapsulation and delivery strategy." @default.
• W3206096472 created "2021-10-25" @default.
• W3206096472 creator A5015671255 @default.
• W3206096472 creator A5031473508 @default.
• W3206096472 creator A5051717534 @default.
• W3206096472 creator A5060461431 @default.
• W3206096472 date "2021-12-01" @default.
• W3206096472 modified "2023-10-17" @default.
• W3206096472 title "Self-coacervation of carboxymethyl chitosan as a pH-responsive encapsulation and delivery strategy" @default.
• W3206096472 cites W1964544026 @default.
• W3206096472 cites W2023456069 @default.
• W3206096472 cites W2070585894 @default.
• W3206096472 cites W2123131721 @default.
• W3206096472 cites W2343130208 @default.
• W3206096472 cites W2613222585 @default.
• W3206096472 cites W2740195247 @default.
• W3206096472 cites W2749558425 @default.
• W3206096472 cites W2755822908 @default.
• W3206096472 cites W2803674762 @default.
• W3206096472 cites W2803935165 @default.
• W3206096472 cites W2809566782 @default.
• W3206096472 cites W2896121415 @default.
• W3206096472 cites W2897774198 @default.
• W3206096472 cites W2900836951 @default.
• W3206096472 cites W2911736778 @default.
• W3206096472 cites W2936163605 @default.
• W3206096472 cites W2938200034 @default.
• W3206096472 cites W2939185616 @default.
• W3206096472 cites W2940405350 @default.
• W3206096472 cites W2954756085 @default.
• W3206096472 cites W2967792383 @default.
• W3206096472 cites W2970296690 @default.
• W3206096472 cites W2985976898 @default.
• W3206096472 cites W3009815366 @default.
• W3206096472 cites W3012323908 @default.
• W3206096472 cites W3044849960 @default.
• W3206096472 cites W3080574111 @default.
• W3206096472 cites W3088014983 @default.
• W3206096472 cites W3088812711 @default.
• W3206096472 cites W3133168909 @default.
• W3206096472 cites W3176223668 @default.
• W3206096472 doi "https://doi.org/10.1016/j.ijbiomac.2021.10.072" @default.
• W3206096472 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34678379" @default.
• W3206096472 hasPublicationYear "2021" @default.
• W3206096472 type Work @default.
• W3206096472 sameAs 3206096472 @default.
• W3206096472 citedByCount "15" @default.
• W3206096472 countsByYear W32060964722022 @default.
• W3206096472 countsByYear W32060964722023 @default.
• W3206096472 crossrefType "journal-article" @default.
• W3206096472 hasAuthorship W3206096472A5015671255 @default.
• W3206096472 hasAuthorship W3206096472A5031473508 @default.
• W3206096472 hasAuthorship W3206096472A5051717534 @default.
• W3206096472 hasAuthorship W3206096472A5060461431 @default.
• W3206096472 hasConcept C127413603 @default.
• W3206096472 hasConcept C160892712 @default.
• W3206096472 hasConcept C178790620 @default.
• W3206096472 hasConcept C181199279 @default.
• W3206096472 hasConcept C184651966 @default.
• W3206096472 hasConcept C185592680 @default.
• W3206096472 hasConcept C187428577 @default.
• W3206096472 hasConcept C2779732960 @default.
• W3206096472 hasConcept C42360764 @default.
• W3206096472 hasConcept C43617362 @default.
• W3206096472 hasConcept C83029808 @default.
• W3206096472 hasConcept C90260826 @default.
• W3206096472 hasConcept C96294017 @default.
• W3206096472 hasConceptScore W3206096472C127413603 @default.
• W3206096472 hasConceptScore W3206096472C160892712 @default.
• W3206096472 hasConceptScore W3206096472C178790620 @default.
• W3206096472 hasConceptScore W3206096472C181199279 @default.
• W3206096472 hasConceptScore W3206096472C184651966 @default.
• W3206096472 hasConceptScore W3206096472C185592680 @default.
• W3206096472 hasConceptScore W3206096472C187428577 @default.
• W3206096472 hasConceptScore W3206096472C2779732960 @default.
• W3206096472 hasConceptScore W3206096472C42360764 @default.
• W3206096472 hasConceptScore W3206096472C43617362 @default.
• W3206096472 hasConceptScore W3206096472C83029808 @default.
• W3206096472 hasConceptScore W3206096472C90260826 @default.
• W3206096472 hasConceptScore W3206096472C96294017 @default.
• W3206096472 hasLocation W32060964721 @default.
• W3206096472 hasLocation W32060964722 @default.
• W3206096472 hasOpenAccess W3206096472 @default.
• W3206096472 hasPrimaryLocation W32060964721 @default.
• W3206096472 hasRelatedWork W2007425377 @default.
• W3206096472 hasRelatedWork W2027122161 @default.
• W3206096472 hasRelatedWork W2052436793 @default.
• W3206096472 hasRelatedWork W2053082810 @default.
• W3206096472 hasRelatedWork W2065530528 @default.
• W3206096472 hasRelatedWork W2090088192 @default.
• W3206096472 hasRelatedWork W2359926239 @default.
• W3206096472 hasRelatedWork W2482262804 @default.
• W3206096472 hasRelatedWork W4318253439 @default.
• W3206096472 hasRelatedWork W4322771063 @default.
• W3206096472 hasVolume "192" @default.
• W3206096472 isParatext "false" @default.
• W3206096472 isRetracted "false" @default.
• W3206096472 magId "3206096472" @default.

• next