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• W3206108889 abstract "Introduction: We present a rare case of vocal fold paresis after administration of the Moderna COVID-19 vaccine. We recognize the significance and possibility of a vocal fold paresis effect from the Moderna COVID-19 vaccine, and examine possible reasons for the inflammatory adverse reaction to the COVID-19 vaccine. Given the recent introduction and authorization of mRNA COVID-19 vaccines, their safety and potential complications have not been entirely assessed. We introduce what we believe to be the first report of an adverse laryngological reaction to the Moderna COVID-19 vaccine. The patient reported acute-onset voice changes 3 days after administration. This case suggests potential complications from mRNA COVID-19 vaccines in order to inform the otolaryngological society and medical community at large of such unforeseen adverse complication. It is late breaking due to the timeline of vaccine administration creating the pool of candidates to study for vaccination responses. Methods: Retrospective case presentation. Results: A 28-year-old woman with no prior medical history presented in our outpatient department with a 2-month history of persistent complaint of sudden voice changes 3 days after receiving the second dose of the Moderna COVID-19 vaccine. The patient stated she noticed her voice becoming more fatigued, hoarser, and diminished in volume. She denied any recent viral illnesses and any additional symptoms. Results of videostroboscopic investigation revealed mild weakness of the left true vocal fold with decreased tensioning with phonation. Also noted was reduced mobility and decreased glottic closure that improved with higher pitches. Without any further confirmatory etiologies of this patients' presentation, we propose the likely source of this patient's vocal cord paresis is likely due to an inflammatory adverse reaction to the COVID- 19 vaccine with a review of recent literature regarding neuropathic sequelae from the mRNA vaccines. Conclusion: The case presented here adds an additional differential for a possible side effect of the Moderna COVID-19 vaccine. A complete and detailed history is imperative when patients present with hoarseness and voice changes after receiving certain vaccines as to target the etiology of the source." @default.
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• W3206108889 date "2021-09-01" @default.
• W3206108889 modified "2023-09-27" @default.
• W3206108889 title "Laryngology/Broncho-Esophagology" @default.
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