FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3206215703> ?p ?o ?g. }

• W3206215703 endingPage "25" @default.
• W3206215703 startingPage "19" @default.
• W3206215703 abstract "Carbon dioxide (CO2) gas is well characterized for medical applications. It is a chemically stable, biocompatible agent that has a long history of traditional use (in natural “mofettes”) particularly in Hungary, as a natural infallible remedy. Medical CO2 gas has been widely used in various area of medicine, mostly in surgical laparoscopy and endoscopic procedures in gastroenterology as an insufflation gas, since it is considered as an inert gas without side effects and the residuals easily absorbed in vascular tissues. On the other hand, the scope of intended use in case of transdermal or intradermal application is substantially different. Based on its primary mechanism of action carbon dioxide along with some other metabolites can cause prompt vasodilation of precapillary sphincters of blood vessels, and consequently a reduction of peripheral resistance and an increase the flow of microcirculation in tissues. Additionally, an increase in perivascular partial oxygen pressure in tissues (tcPO2) has been detected, because of a shift on the oxyhemoglobin dissociation curve, which resulted in an overall enhancement of oxygenation for cells. Scientific literature revealed some other aspects of physiology during transdermal CO2 gas administration, mainly in the field of microcirculation and tissue oxygenation. In this report we confirm the rate of absorption and the systemic elimination and highlight the principles of calculation for distribution and dosing utilizing the methodology of stable isotope ratio analysis. All these data may provide at least one further step supporting the use of carbon dioxide as an effective, non-invasive, convenient therapy. For the future this low-cost treatment option can be considered either (i) as a therapy with a reasonable cost-effectiveness ratio; or (ii) as an adjuvant therapy in rehabilitation with significant increase in quality of life for patients, alternatively (iii) as a prevention transdermal CO2 may provide a safe method for public access with a potential health benefit and reducing the symptoms of arterial and venous disease development." @default.
• W3206215703 created "2021-10-25" @default.
• W3206215703 date "2021-05-28" @default.
• W3206215703 modified "2023-09-30" @default.
• W3206215703 title "Methodological aspects of dose calculations in transdermal carbon dioxide therapy: estimation of absorbed dose and confirmation of systemic distribution" @default.
• W3206215703 cites W148657580 @default.
• W3206215703 cites W1856969622 @default.
• W3206215703 cites W1966055249 @default.
• W3206215703 cites W1979952782 @default.
• W3206215703 cites W2020978512 @default.
• W3206215703 cites W2025904577 @default.
• W3206215703 cites W2029455556 @default.
• W3206215703 cites W2043773779 @default.
• W3206215703 cites W2060766808 @default.
• W3206215703 cites W2065967052 @default.
• W3206215703 cites W2075738251 @default.
• W3206215703 cites W2083345502 @default.
• W3206215703 cites W2133382198 @default.
• W3206215703 cites W2163881134 @default.
• W3206215703 cites W2532874665 @default.
• W3206215703 cites W2588796525 @default.
• W3206215703 cites W2789493801 @default.
• W3206215703 cites W2896586702 @default.
• W3206215703 cites W2903419849 @default.
• W3206215703 cites W2967338436 @default.
• W3206215703 cites W2990617229 @default.
• W3206215703 cites W4240594899 @default.
• W3206215703 cites W4249972245 @default.
• W3206215703 doi "https://doi.org/10.37281/drcsf/2.1.3" @default.
• W3206215703 hasPublicationYear "2021" @default.
• W3206215703 type Work @default.
• W3206215703 sameAs 3206215703 @default.
• W3206215703 citedByCount "1" @default.
• W3206215703 countsByYear W32062157032021 @default.
• W3206215703 crossrefType "journal-article" @default.
• W3206215703 hasBestOaLocation W32062157031 @default.
• W3206215703 hasConcept C126322002 @default.
• W3206215703 hasConcept C12722491 @default.
• W3206215703 hasConcept C136229726 @default.
• W3206215703 hasConcept C178790620 @default.
• W3206215703 hasConcept C185592680 @default.
• W3206215703 hasConcept C205679159 @default.
• W3206215703 hasConcept C530467964 @default.
• W3206215703 hasConcept C71924100 @default.
• W3206215703 hasConcept C98274493 @default.
• W3206215703 hasConceptScore W3206215703C126322002 @default.
• W3206215703 hasConceptScore W3206215703C12722491 @default.
• W3206215703 hasConceptScore W3206215703C136229726 @default.
• W3206215703 hasConceptScore W3206215703C178790620 @default.
• W3206215703 hasConceptScore W3206215703C185592680 @default.
• W3206215703 hasConceptScore W3206215703C205679159 @default.
• W3206215703 hasConceptScore W3206215703C530467964 @default.
• W3206215703 hasConceptScore W3206215703C71924100 @default.
• W3206215703 hasConceptScore W3206215703C98274493 @default.
• W3206215703 hasLocation W32062157031 @default.
• W3206215703 hasLocation W32062157032 @default.
• W3206215703 hasOpenAccess W3206215703 @default.
• W3206215703 hasPrimaryLocation W32062157031 @default.
• W3206215703 hasRelatedWork W1971433131 @default.
• W3206215703 hasRelatedWork W1985638211 @default.
• W3206215703 hasRelatedWork W2011357206 @default.
• W3206215703 hasRelatedWork W2017945832 @default.
• W3206215703 hasRelatedWork W2050841130 @default.
• W3206215703 hasRelatedWork W2314599041 @default.
• W3206215703 hasRelatedWork W2511316169 @default.
• W3206215703 hasRelatedWork W2748952813 @default.
• W3206215703 hasRelatedWork W2899084033 @default.
• W3206215703 hasRelatedWork W2949537349 @default.
• W3206215703 isParatext "false" @default.
• W3206215703 isRetracted "false" @default.
• W3206215703 magId "3206215703" @default.
• W3206215703 workType "article" @default.