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• W3206231265 abstract "Inulin is a highly effective prebiotic and an attractive alternative to antibiotic growth promoters for increasing production and maintaining health in chickens. However, how inulin elicits its effects on members of the intestinal microbiota is unknown, even though their importance for energy metabolism and the health of chickens is well documented. A combination of 16S rRNA Illumina sequencing and transcriptomic analysis was used to investigate the effects of supplementing a corn-based basal diet with 1, 2, or 4% inulin or 400 ppm bacitracin on the composition, diversity and activities of carbohydrate-metabolizing organisms (CMOs) in the cecal microbiota of broiler chickens. We found that members of Bacteroides were the most abundant non-starch degrading CMOs, contributing 43.6–52.1% of total glycoside hydrolase genes and 34.6–47.1% activity to the meta-transcriptomes of chickens in the different dietary groups, although members of Parabacteroides , Prevotella , Alistipes , Clostridium , Barnesiella , Blastocystis , Faecalibacterium and others were also actively involved. Inulin and bacitracin inclusion in the basal diet did not change significantly the composition or diversity of these CMOs. Inulin supplementation at three levels promoted the activities of Bacteroides , Prevotella and Bifidobacterium , and 2% level appears to be the most optimal dosage for bifidobacterial activity." @default.
• W3206231265 created "2021-10-25" @default.
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• W3206231265 date "2021-10-21" @default.
• W3206231265 modified "2023-10-16" @default.
• W3206231265 title "Dietary inulin supplementation modulates the composition and activities of carbohydrate-metabolizing organisms in the cecal microbiota of broiler chickens" @default.
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• W3206231265 doi "https://doi.org/10.1371/journal.pone.0258663" @default.
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