FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3206288618> ?p ?o ?g. }

• W3206288618 endingPage "962" @default.
• W3206288618 startingPage "955" @default.
• W3206288618 abstract "Despite the clear effects and harm of the Bisphenol-A (BPH-A) chemical, it is one of the highest produced chemicals worldwide. The main areas of use include building materials, from automotive to food materials. It is important to find therapeutic agents against the damage caused by the BPH-A. Bisphenol A exposure is the major cause of increased oxidative stress (OS) and mitochondrial dysfunction, especially in cells. Thus, our study aimed to research the protective effect of selenium in BPH-A-induced SH-SY5Y neuroblastoma cells. The SH-SY5Y cells were divided into 4 groups as 1- Control group: No drug was applied to these cells. 2- BPH-A group: Bisphenol A was incubated with 100 µM for 24 hours. 3- BPH-A+Na-Se group: This group was incubated with BPH-A for 24 hours. Na-Se (1 µM) was added in the last 2 hours of the 24 hours. 4- Na-Se group: Na-Se was incubated with 1 µM for 2 hours. In the cells, intracellular ROS and JC-1 levels were highest in the BPH-A group, although there was a significant reduction in the selenium-treated group (BPH-A+Na-Se). In addition to these, when the Caspase-3 and Caspase-9 enzyme activities were examined between the groups, it was seen that Selenium reduces the increased caspase activity caused by BPH-A. Finally, when the apoptosis and MTT analysis results between the groups were examined, it was observed that apoptosis and MTT levels were highest in the BPH-A group, while it was significantly lower in the Na-Se group compared to the BPH-A group. In conclusion, this study revealed that Selenium, with its antioxidant properties, can be used as a neuroprotective agent by reducing BPH-A-induced oxidative stress." @default.
• W3206288618 created "2021-10-25" @default.
• W3206288618 creator A5057389878 @default.
• W3206288618 date "2020-12-31" @default.
• W3206288618 modified "2023-10-02" @default.
• W3206288618 title "Protective role of selenium against bisphenol-A induced oxidative stress, cytokine generation and apoptosis in SH-SY5Y neuronal cell line" @default.
• W3206288618 cites W1903582200 @default.
• W3206288618 cites W1963522150 @default.
• W3206288618 cites W1970358298 @default.
• W3206288618 cites W1986779275 @default.
• W3206288618 cites W2020338693 @default.
• W3206288618 cites W2021276141 @default.
• W3206288618 cites W2094156327 @default.
• W3206288618 cites W2152586799 @default.
• W3206288618 cites W2162830803 @default.
• W3206288618 cites W2323958423 @default.
• W3206288618 cites W2325336945 @default.
• W3206288618 cites W2551825335 @default.
• W3206288618 cites W2586967350 @default.
• W3206288618 cites W2592606137 @default.
• W3206288618 cites W2771580952 @default.
• W3206288618 cites W2884517527 @default.
• W3206288618 cites W2891891203 @default.
• W3206288618 cites W2905174471 @default.
• W3206288618 cites W2921318330 @default.
• W3206288618 cites W2935879916 @default.
• W3206288618 cites W2953517790 @default.
• W3206288618 cites W3000047497 @default.
• W3206288618 cites W3005881558 @default.
• W3206288618 cites W3010858630 @default.
• W3206288618 cites W3016048369 @default.
• W3206288618 cites W3033821678 @default.
• W3206288618 cites W3035080265 @default.
• W3206288618 cites W3048777645 @default.
• W3206288618 cites W3080193067 @default.
• W3206288618 cites W3106406346 @default.
• W3206288618 doi "https://doi.org/10.37212/jcnos.1005692" @default.
• W3206288618 hasPublicationYear "2020" @default.
• W3206288618 type Work @default.
• W3206288618 sameAs 3206288618 @default.
• W3206288618 citedByCount "1" @default.
• W3206288618 countsByYear W32062886182023 @default.
• W3206288618 crossrefType "journal-article" @default.
• W3206288618 hasAuthorship W3206288618A5057389878 @default.
• W3206288618 hasBestOaLocation W32062886181 @default.
• W3206288618 hasConcept C126322002 @default.
• W3206288618 hasConcept C134018914 @default.
• W3206288618 hasConcept C153911025 @default.
• W3206288618 hasConcept C166595027 @default.
• W3206288618 hasConcept C16685009 @default.
• W3206288618 hasConcept C178790620 @default.
• W3206288618 hasConcept C185592680 @default.
• W3206288618 hasConcept C190283241 @default.
• W3206288618 hasConcept C2776151105 @default.
• W3206288618 hasConcept C2776715637 @default.
• W3206288618 hasConcept C2779083432 @default.
• W3206288618 hasConcept C2779684741 @default.
• W3206288618 hasConcept C2779848963 @default.
• W3206288618 hasConcept C2780783641 @default.
• W3206288618 hasConcept C54355233 @default.
• W3206288618 hasConcept C553756173 @default.
• W3206288618 hasConcept C55493867 @default.
• W3206288618 hasConcept C71924100 @default.
• W3206288618 hasConcept C79879829 @default.
• W3206288618 hasConcept C81885089 @default.
• W3206288618 hasConcept C86803240 @default.
• W3206288618 hasConcept C98274493 @default.
• W3206288618 hasConceptScore W3206288618C126322002 @default.
• W3206288618 hasConceptScore W3206288618C134018914 @default.
• W3206288618 hasConceptScore W3206288618C153911025 @default.
• W3206288618 hasConceptScore W3206288618C166595027 @default.
• W3206288618 hasConceptScore W3206288618C16685009 @default.
• W3206288618 hasConceptScore W3206288618C178790620 @default.
• W3206288618 hasConceptScore W3206288618C185592680 @default.
• W3206288618 hasConceptScore W3206288618C190283241 @default.
• W3206288618 hasConceptScore W3206288618C2776151105 @default.
• W3206288618 hasConceptScore W3206288618C2776715637 @default.
• W3206288618 hasConceptScore W3206288618C2779083432 @default.
• W3206288618 hasConceptScore W3206288618C2779684741 @default.
• W3206288618 hasConceptScore W3206288618C2779848963 @default.
• W3206288618 hasConceptScore W3206288618C2780783641 @default.
• W3206288618 hasConceptScore W3206288618C54355233 @default.
• W3206288618 hasConceptScore W3206288618C553756173 @default.
• W3206288618 hasConceptScore W3206288618C55493867 @default.
• W3206288618 hasConceptScore W3206288618C71924100 @default.
• W3206288618 hasConceptScore W3206288618C79879829 @default.
• W3206288618 hasConceptScore W3206288618C81885089 @default.
• W3206288618 hasConceptScore W3206288618C86803240 @default.
• W3206288618 hasConceptScore W3206288618C98274493 @default.
• W3206288618 hasIssue "3" @default.
• W3206288618 hasLocation W32062886181 @default.
• W3206288618 hasOpenAccess W3206288618 @default.
• W3206288618 hasPrimaryLocation W32062886181 @default.
• W3206288618 hasRelatedWork W2044424226 @default.
• W3206288618 hasRelatedWork W2337834220 @default.
• W3206288618 hasRelatedWork W2347459042 @default.
• W3206288618 hasRelatedWork W2354238093 @default.
• W3206288618 hasRelatedWork W2376096128 @default.

• next