Matches in SemOpenAlex for { <https://semopenalex.org/work/W3206382076> ?p ?o ?g. }
- W3206382076 abstract "Bin/Amphiphysin/RVS (BAR) domain proteins belong to a superfamily of coiled-coil proteins influencing membrane curvature in eukaryotes and are associated with vesicle biogenesis, vesicle-mediated protein trafficking, and intracellular signaling. Here, we report a bacterial protein with BAR domain-like activity, BdpA, from Shewanella oneidensis MR-1, known to produce redox-active membrane vesicles and micrometer-scale outer membrane extensions (OMEs). BdpA is required for uniform size distribution of membrane vesicles and influences scaffolding of OMEs into a consistent diameter and curvature. Cryo-TEM reveals that a strain lacking BdpA produces lobed, disordered OMEs rather than membrane tubules or narrow chains produced by the wild-type strain. Overexpression of BdpA promotes OME formation during planktonic growth of S. oneidensis where they are not typically observed. Heterologous expression results in OME production in Marinobacter atlanticus and Escherichia coli. Based on the ability of BdpA to alter membrane architecture in vivo, we propose that BdpA and its homologs comprise a newly identified class of bacterial BAR domain-like proteins." @default.
- W3206382076 created "2021-10-25" @default.
- W3206382076 creator A5001461580 @default.
- W3206382076 creator A5011128625 @default.
- W3206382076 creator A5023673953 @default.
- W3206382076 creator A5029662613 @default.
- W3206382076 creator A5032083656 @default.
- W3206382076 creator A5033422802 @default.
- W3206382076 creator A5036669660 @default.
- W3206382076 creator A5048053170 @default.
- W3206382076 creator A5054085214 @default.
- W3206382076 creator A5062136672 @default.
- W3206382076 creator A5079936482 @default.
- W3206382076 creator A5080365508 @default.
- W3206382076 creator A5087339199 @default.
- W3206382076 creator A5090920687 @default.
- W3206382076 date "2021-10-13" @default.
- W3206382076 modified "2023-10-18" @default.
- W3206382076 title "A bacterial membrane sculpting protein with BAR domain-like activity" @default.
- W3206382076 cites W1503277173 @default.
- W3206382076 cites W1505479679 @default.
- W3206382076 cites W1517717999 @default.
- W3206382076 cites W1567548943 @default.
- W3206382076 cites W1568415783 @default.
- W3206382076 cites W1571919210 @default.
- W3206382076 cites W1753222877 @default.
- W3206382076 cites W1914592961 @default.
- W3206382076 cites W1923303716 @default.
- W3206382076 cites W1955394435 @default.
- W3206382076 cites W1963950126 @default.
- W3206382076 cites W1967398671 @default.
- W3206382076 cites W1968623914 @default.
- W3206382076 cites W1971452779 @default.
- W3206382076 cites W1974067508 @default.
- W3206382076 cites W1981559490 @default.
- W3206382076 cites W1989339367 @default.
- W3206382076 cites W1990380758 @default.
- W3206382076 cites W1991131490 @default.
- W3206382076 cites W1993130148 @default.
- W3206382076 cites W1996355353 @default.
- W3206382076 cites W2001244896 @default.
- W3206382076 cites W2003845371 @default.
- W3206382076 cites W2018672567 @default.
- W3206382076 cites W2019691413 @default.
- W3206382076 cites W2020315971 @default.
- W3206382076 cites W2027229485 @default.
- W3206382076 cites W2028899902 @default.
- W3206382076 cites W2029101220 @default.
- W3206382076 cites W2031444021 @default.
- W3206382076 cites W2032113234 @default.
- W3206382076 cites W2036579313 @default.
- W3206382076 cites W2036917159 @default.
- W3206382076 cites W2039541189 @default.
- W3206382076 cites W2049092556 @default.
- W3206382076 cites W2054566118 @default.
- W3206382076 cites W2055903121 @default.
- W3206382076 cites W2056472979 @default.
- W3206382076 cites W2064585995 @default.
- W3206382076 cites W2068349957 @default.
- W3206382076 cites W2073986982 @default.
- W3206382076 cites W2074713036 @default.
- W3206382076 cites W2093809840 @default.
- W3206382076 cites W2099542485 @default.
- W3206382076 cites W2108586733 @default.
- W3206382076 cites W2110158339 @default.
- W3206382076 cites W2113787438 @default.
- W3206382076 cites W2114628856 @default.
- W3206382076 cites W2124210751 @default.
- W3206382076 cites W2125358782 @default.
- W3206382076 cites W2135621733 @default.
- W3206382076 cites W2136384286 @default.
- W3206382076 cites W2136588682 @default.
- W3206382076 cites W2137089508 @default.
- W3206382076 cites W2140734536 @default.
- W3206382076 cites W2144465161 @default.
- W3206382076 cites W2144996654 @default.
- W3206382076 cites W2151624014 @default.
- W3206382076 cites W2158412800 @default.
- W3206382076 cites W2158714788 @default.
- W3206382076 cites W2162792752 @default.
- W3206382076 cites W2163627198 @default.
- W3206382076 cites W2168018807 @default.
- W3206382076 cites W2279413689 @default.
- W3206382076 cites W2336400828 @default.
- W3206382076 cites W2409701406 @default.
- W3206382076 cites W2427061751 @default.
- W3206382076 cites W2478952582 @default.
- W3206382076 cites W2569827218 @default.
- W3206382076 cites W2588438994 @default.
- W3206382076 cites W2589446613 @default.
- W3206382076 cites W2592827120 @default.
- W3206382076 cites W2592949067 @default.
- W3206382076 cites W2609207099 @default.
- W3206382076 cites W2626324097 @default.
- W3206382076 cites W2708931810 @default.
- W3206382076 cites W2753966035 @default.
- W3206382076 cites W2766806286 @default.
- W3206382076 cites W2767437881 @default.
- W3206382076 cites W2773796225 @default.
- W3206382076 cites W2808094455 @default.