Matches in SemOpenAlex for { <https://semopenalex.org/work/W3206520610> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W3206520610 endingPage "S76" @default.
- W3206520610 startingPage "S76" @default.
- W3206520610 abstract "Relevant pharmacokinetic and pharmacodynamic genes will be discussed along with the recent pediatric studies that indicate a shift from the treatment impact of combinatorial to single-gene pharmacogenetics (PGx). Guidelines from the Clinical Pharmacogenetics Implementation Consortium (CPIC) and Pharmacogenomics Knowledge Base (PharmGKB) will be reviewed along with a clinical framework that integrates PGx within evidence-based guidelines. Discussion will include both benefits and limitations of PGx in clinical care. Salma Malik, MD, will present the data that distinguishes the most relevant genes found on commercially available gene panels and review their potential clinical application. Laura Ramsey, PhD, will systematically review recent pediatric PGx studies and data highlighting relevant medication-gene pairs that may impact outcome in pediatric patients with anxiety and depression. Jeffrey Bishop, PharmD, will discuss evidence gradings for genes currently included on PGx tests and how these apply to current and future CPIC guidelines and will invite audience participation using CPIC and PharmGKB websites as clinical support tools. Lisa Namerow, MD, will use a case-based presentation, with audience participation, to review a clinical approach for integrating PGx findings without deviating from evidence-based medicine. Finally, Barbara Coffey, MD, a senior psychopharmacology expert, will comment on “where we are now,” and Jeffrey Strawn, MD, a leading researcher in the field, will discuss “where are we going.” Accumulating data suggest that certain PGx genes impact medication response and tolerability in pediatric patients. Some pharmacokinetic genes affect medication concentrations, which has pragmatic implications for clinicians. These data have prompted clinicians to consider how to best apply PGx results, if available, within the context of evidence-based medicine. Given the availability of PGx testing for genes related to medication tolerance and efficacy, it is important for child and adolescent psychiatrists to enhance their knowledge base by exploring the most up-to-date studies and current guidelines in order to provide clarity on the possible application and limitations of PGx within clinical care." @default.
- W3206520610 created "2021-10-25" @default.
- W3206520610 creator A5008039287 @default.
- W3206520610 creator A5010194987 @default.
- W3206520610 creator A5042629034 @default.
- W3206520610 creator A5078321983 @default.
- W3206520610 date "2021-10-01" @default.
- W3206520610 modified "2023-09-24" @default.
- W3206520610 title "PHARMACOGENETICS 2021: AN EXPLORATION OF THE EVIDENCE FOR RELEVANT GENES AND GENE-MEDICATION PAIRS" @default.
- W3206520610 doi "https://doi.org/10.1016/j.jaac.2021.07.322" @default.
- W3206520610 hasPublicationYear "2021" @default.
- W3206520610 type Work @default.
- W3206520610 sameAs 3206520610 @default.
- W3206520610 citedByCount "0" @default.
- W3206520610 crossrefType "journal-article" @default.
- W3206520610 hasAuthorship W3206520610A5008039287 @default.
- W3206520610 hasAuthorship W3206520610A5010194987 @default.
- W3206520610 hasAuthorship W3206520610A5042629034 @default.
- W3206520610 hasAuthorship W3206520610A5078321983 @default.
- W3206520610 hasConcept C104317684 @default.
- W3206520610 hasConcept C135763542 @default.
- W3206520610 hasConcept C142724271 @default.
- W3206520610 hasConcept C163763905 @default.
- W3206520610 hasConcept C170734499 @default.
- W3206520610 hasConcept C204787440 @default.
- W3206520610 hasConcept C2778375690 @default.
- W3206520610 hasConcept C2779473830 @default.
- W3206520610 hasConcept C54355233 @default.
- W3206520610 hasConcept C55493867 @default.
- W3206520610 hasConcept C55775858 @default.
- W3206520610 hasConcept C71924100 @default.
- W3206520610 hasConcept C86803240 @default.
- W3206520610 hasConcept C98274493 @default.
- W3206520610 hasConceptScore W3206520610C104317684 @default.
- W3206520610 hasConceptScore W3206520610C135763542 @default.
- W3206520610 hasConceptScore W3206520610C142724271 @default.
- W3206520610 hasConceptScore W3206520610C163763905 @default.
- W3206520610 hasConceptScore W3206520610C170734499 @default.
- W3206520610 hasConceptScore W3206520610C204787440 @default.
- W3206520610 hasConceptScore W3206520610C2778375690 @default.
- W3206520610 hasConceptScore W3206520610C2779473830 @default.
- W3206520610 hasConceptScore W3206520610C54355233 @default.
- W3206520610 hasConceptScore W3206520610C55493867 @default.
- W3206520610 hasConceptScore W3206520610C55775858 @default.
- W3206520610 hasConceptScore W3206520610C71924100 @default.
- W3206520610 hasConceptScore W3206520610C86803240 @default.
- W3206520610 hasConceptScore W3206520610C98274493 @default.
- W3206520610 hasIssue "10" @default.
- W3206520610 hasLocation W32065206101 @default.
- W3206520610 hasOpenAccess W3206520610 @default.
- W3206520610 hasPrimaryLocation W32065206101 @default.
- W3206520610 hasRelatedWork W1502803161 @default.
- W3206520610 hasRelatedWork W1970064806 @default.
- W3206520610 hasRelatedWork W2093889398 @default.
- W3206520610 hasRelatedWork W2147549027 @default.
- W3206520610 hasRelatedWork W2533250251 @default.
- W3206520610 hasRelatedWork W2771536533 @default.
- W3206520610 hasRelatedWork W2886595537 @default.
- W3206520610 hasRelatedWork W4313016214 @default.
- W3206520610 hasRelatedWork W55371444 @default.
- W3206520610 hasRelatedWork W560278455 @default.
- W3206520610 hasVolume "60" @default.
- W3206520610 isParatext "false" @default.
- W3206520610 isRetracted "false" @default.
- W3206520610 magId "3206520610" @default.
- W3206520610 workType "article" @default.