Matches in SemOpenAlex for { <https://semopenalex.org/work/W320653078> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W320653078 endingPage "1664" @default.
- W320653078 startingPage "1658" @default.
- W320653078 abstract "Ganoderma lucidum (Fr.) P. Karst. is considered as a panacea in Chinese medicine. This mushroom has been reported to have a number of novel biological activities. Our previous investigations have demonstrated the antioxidant, anti-inflammatory and antitumour activities of aqueous-methanolic extract of G. lucidum occurring in South India. We extended our studies to evaluate the effect of this mushroom extract on the prevention of mammary adenocarcinoma in rats and skin tumour in mice. Mammary tumours were induced by oral administration of 7,12-dimethyl benz[a]anthracene (DMBA) in female Sprague Dawley rats. Skin tumours were induced by topical application of DMBA and promoted by croton oil on Balb/c mice. The experimental results indicated that G. lucidum showed significant tumour reducing activity against DMBA induced mammary and skin tumours in a dose-dependent manner. The administration of the mushroom extract showed profound effect on tumour induction, tumour latency period and tumour proliferation of both mammary tumour as well as skin tumours. The results thus reveal that the aqueous-mehanolic extract of G. lucidum possessed significant protective effect against DMBA induced mammary and skin tumours. Findings suggest the potential therapeutic use of G. lucidum in cancer chemoprevention." @default.
- W320653078 created "2016-06-24" @default.
- W320653078 creator A5000959023 @default.
- W320653078 creator A5021408962 @default.
- W320653078 creator A5066150068 @default.
- W320653078 date "2009-01-01" @default.
- W320653078 modified "2023-09-25" @default.
- W320653078 title "Prevention of mammary adenocarcinoma and skin tumour by Ganoderma lucidum, a medicinal mushroom occurring in South India" @default.
- W320653078 hasPublicationYear "2009" @default.
- W320653078 type Work @default.
- W320653078 sameAs 320653078 @default.
- W320653078 citedByCount "3" @default.
- W320653078 countsByYear W3206530782013 @default.
- W320653078 crossrefType "journal-article" @default.
- W320653078 hasAuthorship W320653078A5000959023 @default.
- W320653078 hasAuthorship W320653078A5021408962 @default.
- W320653078 hasAuthorship W320653078A5066150068 @default.
- W320653078 hasConcept C121608353 @default.
- W320653078 hasConcept C126322002 @default.
- W320653078 hasConcept C2776474821 @default.
- W320653078 hasConcept C2776618520 @default.
- W320653078 hasConcept C2778938436 @default.
- W320653078 hasConcept C2992468417 @default.
- W320653078 hasConcept C2993907526 @default.
- W320653078 hasConcept C555283112 @default.
- W320653078 hasConcept C556039675 @default.
- W320653078 hasConcept C59822182 @default.
- W320653078 hasConcept C71924100 @default.
- W320653078 hasConcept C86803240 @default.
- W320653078 hasConcept C98274493 @default.
- W320653078 hasConceptScore W320653078C121608353 @default.
- W320653078 hasConceptScore W320653078C126322002 @default.
- W320653078 hasConceptScore W320653078C2776474821 @default.
- W320653078 hasConceptScore W320653078C2776618520 @default.
- W320653078 hasConceptScore W320653078C2778938436 @default.
- W320653078 hasConceptScore W320653078C2992468417 @default.
- W320653078 hasConceptScore W320653078C2993907526 @default.
- W320653078 hasConceptScore W320653078C555283112 @default.
- W320653078 hasConceptScore W320653078C556039675 @default.
- W320653078 hasConceptScore W320653078C59822182 @default.
- W320653078 hasConceptScore W320653078C71924100 @default.
- W320653078 hasConceptScore W320653078C86803240 @default.
- W320653078 hasConceptScore W320653078C98274493 @default.
- W320653078 hasIssue "11" @default.
- W320653078 hasLocation W3206530781 @default.
- W320653078 hasOpenAccess W320653078 @default.
- W320653078 hasPrimaryLocation W3206530781 @default.
- W320653078 hasRelatedWork W1973278841 @default.
- W320653078 hasRelatedWork W1975766026 @default.
- W320653078 hasRelatedWork W1978365751 @default.
- W320653078 hasRelatedWork W2011324475 @default.
- W320653078 hasRelatedWork W2012174834 @default.
- W320653078 hasRelatedWork W2020117567 @default.
- W320653078 hasRelatedWork W2062202515 @default.
- W320653078 hasRelatedWork W2097950928 @default.
- W320653078 hasRelatedWork W2116617228 @default.
- W320653078 hasRelatedWork W2123712628 @default.
- W320653078 hasRelatedWork W2139762494 @default.
- W320653078 hasRelatedWork W2304385845 @default.
- W320653078 hasRelatedWork W2321215750 @default.
- W320653078 hasRelatedWork W2340472530 @default.
- W320653078 hasRelatedWork W2380750412 @default.
- W320653078 hasRelatedWork W2592679671 @default.
- W320653078 hasRelatedWork W3025401223 @default.
- W320653078 hasRelatedWork W3100572703 @default.
- W320653078 hasRelatedWork W3151779795 @default.
- W320653078 hasRelatedWork W3136951705 @default.
- W320653078 hasVolume "97" @default.
- W320653078 isParatext "false" @default.
- W320653078 isRetracted "false" @default.
- W320653078 magId "320653078" @default.
- W320653078 workType "article" @default.