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- W3206537315 endingPage "096368972110513" @default.
- W3206537315 startingPage "096368972110513" @default.
- W3206537315 abstract "In bone tissue engineering, tailored biomaterials mimicking mesenchymal stem cells (MSCs) niche could regulate cell behavior and fate decision. The mechanisms, however, remain obscure. Recently, increasing evidence has shown that non-coding RNAs (ncRNAs) are critical modulators of the mechano-induced MSCs’ responses. Mechanosensitive ncRNAs could convert various physical forces into biochemical signals, and orchestrate signaling networks that regulate the osteogenic differentiation of MSCs in their unique microenvironment. In this review, we focus on the mechanosensitive ncRNAs which could interpret mechanical stimuli during the osteogenesis of MSCs, summarize the signaling pathway networks by which these ncRNAs drive MSCs fate, and point out the limitations and the areas waiting for further exploration." @default.
- W3206537315 created "2021-10-25" @default.
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- W3206537315 date "2021-01-01" @default.
- W3206537315 modified "2023-10-18" @default.
- W3206537315 title "Mechanosensitive Non-Coding RNAs in Osteogenesis of Mesenchymal Stem Cells" @default.
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- W3206537315 doi "https://doi.org/10.1177/09636897211051382" @default.
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