Matches in SemOpenAlex for { <https://semopenalex.org/work/W3206564191> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W3206564191 endingPage "222" @default.
- W3206564191 startingPage "216" @default.
- W3206564191 abstract "Rapid results are needed when plasma concentrations of direct oral anticoagulants (DOACs) are required in acute clinical settings. We evaluated the impact of centrifugation time and pneumatic tube transport on DOAC plasma concentrations with the overall aim of reducing turnaround time.Blood samples were spiked with rivaroxaban, apixaban or dabigatran in a low and a high concentration prior to centrifugation for 25 minutes (3163 g) or 5 minutes (3000 g) (n = 20 for each DOAC). Both samples spiked with DOACs (n = 20 for each DOAC) and patient samples (n = 25 in total) were transported manually or by pneumatic tube system samples.For samples spiked with DOAC, statistically significant differences in DOAC plasma concentrations were found between centrifugation times for rivaroxaban in low (P < .05) and high (P < .05) concentrations. Relative bias was below 9% for all DOACs. Statistically significant differences were found between modes of transportation for rivaroxaban (P < .01) and dabigatran (P < .01) in high concentrations. Relative bias was 4%-23% for all DOACs. For patient samples, no statistically significant differences were found between modes of transportation, and relative bias was below 12% for all DOACs.Minor, clinically insignificant, differences regarding centrifugation times were found in DOAC plasma concentrations. Importantly, no significant differences were found according to transportation modes for samples collected from patients. Although statistically significant differences were found depending on mode of transportation of spiked samples, relative bias was clinically acceptable. Thus, reduced centrifugation time and pneumatic tube transport should be considered to reduce turnaround time for rapid measurement of DOAC plasma concentrations." @default.
- W3206564191 created "2021-10-25" @default.
- W3206564191 creator A5013553039 @default.
- W3206564191 creator A5022628217 @default.
- W3206564191 creator A5032673621 @default.
- W3206564191 creator A5066807883 @default.
- W3206564191 creator A5079007680 @default.
- W3206564191 date "2021-10-12" @default.
- W3206564191 modified "2023-09-24" @default.
- W3206564191 title "Impact of centrifugation time and pneumatic tube transport on plasma concentrations of direct oral anticoagulants" @default.
- W3206564191 cites W2097854437 @default.
- W3206564191 cites W2136489990 @default.
- W3206564191 cites W2162508946 @default.
- W3206564191 cites W2544588396 @default.
- W3206564191 cites W2603123984 @default.
- W3206564191 cites W2743242016 @default.
- W3206564191 cites W2769760280 @default.
- W3206564191 cites W2774163666 @default.
- W3206564191 cites W2789895945 @default.
- W3206564191 cites W2799804580 @default.
- W3206564191 cites W2811122126 @default.
- W3206564191 cites W2971121646 @default.
- W3206564191 cites W3082188176 @default.
- W3206564191 doi "https://doi.org/10.1111/ijlh.13729" @default.
- W3206564191 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34638165" @default.
- W3206564191 hasPublicationYear "2021" @default.
- W3206564191 type Work @default.
- W3206564191 sameAs 3206564191 @default.
- W3206564191 citedByCount "0" @default.
- W3206564191 crossrefType "journal-article" @default.
- W3206564191 hasAuthorship W3206564191A5013553039 @default.
- W3206564191 hasAuthorship W3206564191A5022628217 @default.
- W3206564191 hasAuthorship W3206564191A5032673621 @default.
- W3206564191 hasAuthorship W3206564191A5066807883 @default.
- W3206564191 hasAuthorship W3206564191A5079007680 @default.
- W3206564191 hasConcept C126322002 @default.
- W3206564191 hasConcept C185592680 @default.
- W3206564191 hasConcept C2776301958 @default.
- W3206564191 hasConcept C2778661090 @default.
- W3206564191 hasConcept C2778810321 @default.
- W3206564191 hasConcept C2779161974 @default.
- W3206564191 hasConcept C2780638905 @default.
- W3206564191 hasConcept C3020079912 @default.
- W3206564191 hasConcept C43617362 @default.
- W3206564191 hasConcept C71924100 @default.
- W3206564191 hasConcept C7623868 @default.
- W3206564191 hasConcept C98274493 @default.
- W3206564191 hasConceptScore W3206564191C126322002 @default.
- W3206564191 hasConceptScore W3206564191C185592680 @default.
- W3206564191 hasConceptScore W3206564191C2776301958 @default.
- W3206564191 hasConceptScore W3206564191C2778661090 @default.
- W3206564191 hasConceptScore W3206564191C2778810321 @default.
- W3206564191 hasConceptScore W3206564191C2779161974 @default.
- W3206564191 hasConceptScore W3206564191C2780638905 @default.
- W3206564191 hasConceptScore W3206564191C3020079912 @default.
- W3206564191 hasConceptScore W3206564191C43617362 @default.
- W3206564191 hasConceptScore W3206564191C71924100 @default.
- W3206564191 hasConceptScore W3206564191C7623868 @default.
- W3206564191 hasConceptScore W3206564191C98274493 @default.
- W3206564191 hasIssue "1" @default.
- W3206564191 hasLocation W32065641911 @default.
- W3206564191 hasLocation W32065641912 @default.
- W3206564191 hasOpenAccess W3206564191 @default.
- W3206564191 hasPrimaryLocation W32065641911 @default.
- W3206564191 hasRelatedWork W2046188252 @default.
- W3206564191 hasRelatedWork W2083901189 @default.
- W3206564191 hasRelatedWork W2093259736 @default.
- W3206564191 hasRelatedWork W2134062404 @default.
- W3206564191 hasRelatedWork W2603244127 @default.
- W3206564191 hasRelatedWork W2789972226 @default.
- W3206564191 hasRelatedWork W2799614734 @default.
- W3206564191 hasRelatedWork W3182665476 @default.
- W3206564191 hasRelatedWork W3190011143 @default.
- W3206564191 hasRelatedWork W4288066229 @default.
- W3206564191 hasVolume "44" @default.
- W3206564191 isParatext "false" @default.
- W3206564191 isRetracted "false" @default.
- W3206564191 magId "3206564191" @default.
- W3206564191 workType "article" @default.