FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3206607013> ?p ?o ?g. }

• W3206607013 abstract "Vaccination is essential for controlling the coronavirus disease (COVID-19) pandemic. An effective time-course strategy for the allocation of COVID-19 vaccines is crucial given that the global vaccine supply will still be limited in some countries/regions in the near future and that mutant strains have emerged and will continue to spread worldwide. Both asymptomatic and symptomatic transmission have played major roles in the COVID-19 pandemic, which can only be properly described as a typical non-Markovian process. However, the prioritization of vaccines in the non-Markovian framework still lacks sufficient research, and the underlying mechanism of the time-course vaccine allocation optimization has not yet been uncovered. In this paper, based on an age-stratified compartmental model calibrated through clinical and epidemiological data, we propose optimal vaccination strategies (OVS) through steady-state prediction in the non-Markovian framework. This OVS outperforms other empirical vaccine prioritization approaches in minimizing cumulative infections, cumulative deaths, or years of life lost caused by the pandemic. We found that there exists a fast decline in the prevention efficiency of vaccination if vaccines are solely administered to a selected age group, which indicates that the widely adopted strategy to continuously vaccinate high-risk group is not optimal. Through mathematical analysis of the model, we reveal that dynamic vaccine allocations to combinations of different age groups is necessary to achieve optimal vaccine prioritization. Our work not only provides meaningful references for vaccination in countries currently lacking vaccines and for vaccine allocation strategies to prevent mutant strains in the future, but also reveals the mechanism of dynamic vaccine allocation optimization, forming a theoretical and modelling framework empirically applicable to the optimal time-course prioritization.Funding: This work was supported by the Hong Kong Baptist University (HKBU) Strategic Development Fund. This research was conducted using the resources of the High- Performance Computing Cluster Centre at HKBU, which receives funding from the Hong Kong Research Grant Council and the HKBU. Declaration of Interests: The authors declare that they have no competing interests." @default.
• W3206607013 created "2021-10-25" @default.
• W3206607013 creator A5029297296 @default.
• W3206607013 creator A5034614141 @default.
• W3206607013 creator A5034661396 @default.
• W3206607013 date "2021-01-01" @default.
• W3206607013 modified "2023-10-18" @default.
• W3206607013 title "Mechanism of Optimal Time-Course COVID-19 Vaccine Prioritization Based on Non-Markovian Steady-State Prediction" @default.
• W3206607013 cites W1971536112 @default.
• W3206607013 cites W1994731130 @default.
• W3206607013 cites W2046763850 @default.
• W3206607013 cites W2084538642 @default.
• W3206607013 cites W2755849266 @default.
• W3206607013 cites W3012756997 @default.
• W3206607013 cites W3015571324 @default.
• W3206607013 cites W3020001547 @default.
• W3206607013 cites W3029878358 @default.
• W3206607013 cites W3031834099 @default.
• W3206607013 cites W3045248985 @default.
• W3206607013 cites W3082370774 @default.
• W3206607013 cites W3091922182 @default.
• W3206607013 cites W3099011804 @default.
• W3206607013 cites W3103145119 @default.
• W3206607013 cites W3111255098 @default.
• W3206607013 cites W3114214147 @default.
• W3206607013 cites W3114735216 @default.
• W3206607013 cites W3123021790 @default.
• W3206607013 cites W3129969458 @default.
• W3206607013 cites W3140873963 @default.
• W3206607013 doi "https://doi.org/10.2139/ssrn.3940627" @default.
• W3206607013 hasPublicationYear "2021" @default.
• W3206607013 type Work @default.
• W3206607013 sameAs 3206607013 @default.
• W3206607013 citedByCount "0" @default.
• W3206607013 crossrefType "journal-article" @default.
• W3206607013 hasAuthorship W3206607013A5029297296 @default.
• W3206607013 hasAuthorship W3206607013A5034614141 @default.
• W3206607013 hasAuthorship W3206607013A5034661396 @default.
• W3206607013 hasBestOaLocation W32066070132 @default.
• W3206607013 hasConcept C105795698 @default.
• W3206607013 hasConcept C116675565 @default.
• W3206607013 hasConcept C121332964 @default.
• W3206607013 hasConcept C127413603 @default.
• W3206607013 hasConcept C142724271 @default.
• W3206607013 hasConcept C159047783 @default.
• W3206607013 hasConcept C159886148 @default.
• W3206607013 hasConcept C2777615720 @default.
• W3206607013 hasConcept C2779134260 @default.
• W3206607013 hasConcept C3006700255 @default.
• W3206607013 hasConcept C3007834351 @default.
• W3206607013 hasConcept C3008058167 @default.
• W3206607013 hasConcept C33923547 @default.
• W3206607013 hasConcept C41008148 @default.
• W3206607013 hasConcept C524204448 @default.
• W3206607013 hasConcept C539667460 @default.
• W3206607013 hasConcept C62520636 @default.
• W3206607013 hasConcept C71924100 @default.
• W3206607013 hasConcept C89611455 @default.
• W3206607013 hasConceptScore W3206607013C105795698 @default.
• W3206607013 hasConceptScore W3206607013C116675565 @default.
• W3206607013 hasConceptScore W3206607013C121332964 @default.
• W3206607013 hasConceptScore W3206607013C127413603 @default.
• W3206607013 hasConceptScore W3206607013C142724271 @default.
• W3206607013 hasConceptScore W3206607013C159047783 @default.
• W3206607013 hasConceptScore W3206607013C159886148 @default.
• W3206607013 hasConceptScore W3206607013C2777615720 @default.
• W3206607013 hasConceptScore W3206607013C2779134260 @default.
• W3206607013 hasConceptScore W3206607013C3006700255 @default.
• W3206607013 hasConceptScore W3206607013C3007834351 @default.
• W3206607013 hasConceptScore W3206607013C3008058167 @default.
• W3206607013 hasConceptScore W3206607013C33923547 @default.
• W3206607013 hasConceptScore W3206607013C41008148 @default.
• W3206607013 hasConceptScore W3206607013C524204448 @default.
• W3206607013 hasConceptScore W3206607013C539667460 @default.
• W3206607013 hasConceptScore W3206607013C62520636 @default.
• W3206607013 hasConceptScore W3206607013C71924100 @default.
• W3206607013 hasConceptScore W3206607013C89611455 @default.
• W3206607013 hasLocation W32066070131 @default.
• W3206607013 hasLocation W32066070132 @default.
• W3206607013 hasOpenAccess W3206607013 @default.
• W3206607013 hasPrimaryLocation W32066070131 @default.
• W3206607013 hasRelatedWork W3009669391 @default.
• W3206607013 hasRelatedWork W3036314732 @default.
• W3206607013 hasRelatedWork W3113664224 @default.
• W3206607013 hasRelatedWork W3176864053 @default.
• W3206607013 hasRelatedWork W3198183218 @default.
• W3206607013 hasRelatedWork W4200329650 @default.
• W3206607013 hasRelatedWork W4205317059 @default.
• W3206607013 hasRelatedWork W4206669628 @default.
• W3206607013 hasRelatedWork W4382894326 @default.
• W3206607013 hasRelatedWork W3127156785 @default.
• W3206607013 isParatext "false" @default.
• W3206607013 isRetracted "false" @default.
• W3206607013 magId "3206607013" @default.
• W3206607013 workType "article" @default.