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- W3206615596 abstract "Heart diastole is a complex of numerous interrelated processes that determine how the heart chambers will be filled with blood. Two main features of the filling of the left atrium are: ventricular relaxation and effective compliance of the chamber. Ventricular relaxation is the complex of energy-dependent processes and the relaxation disturbance is an early event in the conditions of the miocardiac ischemia. Disturbed relaxation prolongs the increase of the miocardiac tonus during the diastole, so the elevation of the diastolic pressure is recorded even before the patient develops the angina and there arise ECG changes. The increased end-diastolic pressure at any level of diastolic volume can clinically result in dyspnea. In the acute phase of the miocardiac infarction first there is the initial increase and then the reduction of the left atrium compliance. With the loss of the elastic characteristics of the myocardium, the systolic dysfunction is preceded by the disturbed passive component of the left atrium filling, that is, the compliance. The onset of the restrictive form of the left atrium filling in patients with the acute myocardium infarction is the prediction of the pathological remodeling of the left atrium, the deterioration of the systolic function and the unfavorable long-term prognosis for these patients." @default.
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- W3206615596 date "2001-01-01" @default.
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- W3206615596 title "Left ventricle diastolic dysfunction in coronary artery disease" @default.
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