Matches in SemOpenAlex for { <https://semopenalex.org/work/W3206695716> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W3206695716 abstract "The human gut microbiota composition plays an important role in human health. Long-term diet intervention may shape human gut microbiome. Therefore, many studies focus on discovering links between long-term diets and gut microbiota composition. This study aimed to incorporate the phylogenetic relationships between the operational taxonomic units (OTUs) into the diet-microbe association analysis, using a Bayesian hierarchical negative binomial (NB) model. We regularized the dispersion parameter of the negative binomial distribution by assuming a mean-dispersion association. A simulation study showed that, if over-dispersion is present in the microbiome data, our approach performed better in terms of mean squared error (MSE) of the slope-estimates compared to the standard NB regression model or a Bayesian hierarchical NB model without including the phylogenetic relationships. Data of the Healthy Life in an Urban Setting (HELIUS) study showed that for some phylogenetic families the (posterior) variances of the slope-estimates were decreasing when including the phylogenetic relationships into the analyses. In contrast, when OTUs of the same family were not similarly affected by the food item, some bias was introduced, leading to larger (posterior) variances of the slope-estimates. Overall, the Bayesian hierarchical NB model, with a dependency between the mean and dispersion parameters, proved to be a robust method for analyzing diet-microbe associations." @default.
- W3206695716 created "2021-10-25" @default.
- W3206695716 creator A5031804038 @default.
- W3206695716 creator A5051056050 @default.
- W3206695716 creator A5063972398 @default.
- W3206695716 date "2021-10-07" @default.
- W3206695716 modified "2023-09-25" @default.
- W3206695716 title "A Bayesian Negative Binomial Hierarchical Model for Identifying Diet–Gut Microbiome Associations" @default.
- W3206695716 cites W1513618424 @default.
- W3206695716 cites W1516274582 @default.
- W3206695716 cites W1968105193 @default.
- W3206695716 cites W2004014148 @default.
- W3206695716 cites W2050046599 @default.
- W3206695716 cites W2057411492 @default.
- W3206695716 cites W2114104545 @default.
- W3206695716 cites W2116584864 @default.
- W3206695716 cites W2135717147 @default.
- W3206695716 cites W2143777796 @default.
- W3206695716 cites W2179438025 @default.
- W3206695716 cites W2395461901 @default.
- W3206695716 cites W2563720483 @default.
- W3206695716 cites W2567421046 @default.
- W3206695716 cites W2577537660 @default.
- W3206695716 cites W2581853214 @default.
- W3206695716 cites W2605052214 @default.
- W3206695716 cites W2609405928 @default.
- W3206695716 cites W2767984705 @default.
- W3206695716 cites W2792247208 @default.
- W3206695716 cites W2805009121 @default.
- W3206695716 cites W2810671429 @default.
- W3206695716 cites W2886557383 @default.
- W3206695716 cites W2924771864 @default.
- W3206695716 cites W2945521319 @default.
- W3206695716 cites W2999951287 @default.
- W3206695716 cites W3016679588 @default.
- W3206695716 cites W3017216193 @default.
- W3206695716 cites W3137215658 @default.
- W3206695716 doi "https://doi.org/10.3389/fmicb.2021.711861" @default.
- W3206695716 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8529249" @default.
- W3206695716 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34690956" @default.
- W3206695716 hasPublicationYear "2021" @default.
- W3206695716 type Work @default.
- W3206695716 sameAs 3206695716 @default.
- W3206695716 citedByCount "0" @default.
- W3206695716 crossrefType "journal-article" @default.
- W3206695716 hasAuthorship W3206695716A5031804038 @default.
- W3206695716 hasAuthorship W3206695716A5051056050 @default.
- W3206695716 hasAuthorship W3206695716A5063972398 @default.
- W3206695716 hasBestOaLocation W32066957161 @default.
- W3206695716 hasConcept C100906024 @default.
- W3206695716 hasConcept C104317684 @default.
- W3206695716 hasConcept C105795698 @default.
- W3206695716 hasConcept C107673813 @default.
- W3206695716 hasConcept C143121216 @default.
- W3206695716 hasConcept C160234255 @default.
- W3206695716 hasConcept C191413810 @default.
- W3206695716 hasConcept C193252679 @default.
- W3206695716 hasConcept C199335787 @default.
- W3206695716 hasConcept C33923547 @default.
- W3206695716 hasConcept C41054675 @default.
- W3206695716 hasConcept C54355233 @default.
- W3206695716 hasConcept C61224824 @default.
- W3206695716 hasConcept C86803240 @default.
- W3206695716 hasConceptScore W3206695716C100906024 @default.
- W3206695716 hasConceptScore W3206695716C104317684 @default.
- W3206695716 hasConceptScore W3206695716C105795698 @default.
- W3206695716 hasConceptScore W3206695716C107673813 @default.
- W3206695716 hasConceptScore W3206695716C143121216 @default.
- W3206695716 hasConceptScore W3206695716C160234255 @default.
- W3206695716 hasConceptScore W3206695716C191413810 @default.
- W3206695716 hasConceptScore W3206695716C193252679 @default.
- W3206695716 hasConceptScore W3206695716C199335787 @default.
- W3206695716 hasConceptScore W3206695716C33923547 @default.
- W3206695716 hasConceptScore W3206695716C41054675 @default.
- W3206695716 hasConceptScore W3206695716C54355233 @default.
- W3206695716 hasConceptScore W3206695716C61224824 @default.
- W3206695716 hasConceptScore W3206695716C86803240 @default.
- W3206695716 hasLocation W32066957161 @default.
- W3206695716 hasLocation W32066957162 @default.
- W3206695716 hasLocation W32066957163 @default.
- W3206695716 hasLocation W32066957164 @default.
- W3206695716 hasOpenAccess W3206695716 @default.
- W3206695716 hasPrimaryLocation W32066957161 @default.
- W3206695716 hasRelatedWork W1976798034 @default.
- W3206695716 hasRelatedWork W2004478598 @default.
- W3206695716 hasRelatedWork W2090974853 @default.
- W3206695716 hasRelatedWork W2090990521 @default.
- W3206695716 hasRelatedWork W2347359446 @default.
- W3206695716 hasRelatedWork W2350205425 @default.
- W3206695716 hasRelatedWork W2382372065 @default.
- W3206695716 hasRelatedWork W3206695716 @default.
- W3206695716 hasRelatedWork W4237509019 @default.
- W3206695716 hasRelatedWork W653594667 @default.
- W3206695716 hasVolume "12" @default.
- W3206695716 isParatext "false" @default.
- W3206695716 isRetracted "false" @default.
- W3206695716 magId "3206695716" @default.
- W3206695716 workType "article" @default.