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- W3206696439 abstract "An organized clinical approach in the diagnosis and management of demyelinating optic neuropathies is important for holistic management of patients. Demyelinating Optic neuropathies are of three different types –a) Optic Neuritis (ON), b) Neuromyelitis Optica and c) Optic neuropathies associated with Myelin Oligodendrocyte Glycoprotein. The later two are often grouped under Neuromyelitis optica spectrum disorders (NMOSD). All three are characterized by the triad of sub-acute vision loss, dys-chromatopsia and peri-ocular pain. From anatomical point of view, ON has also been divided into papillitis, retrobulbar neuritis, optic peri-neuritis and neuro-retinitis. Clinically, ON associated with Multiple sclerosis (ON-MS) is mild in severity, often unilateral and associated with demyelination without axonal loss. Evidence of additional axonal loss is seen in patients with ON associated with NMOSD. The differential diagnoses of ON include infectious, and post-infectious autoimmune conditions, neoplastic, toxic, and hereditary causes. Recognizing red flags is important in wake of long-term implications. Clinico- radiological correlation is another important aspect in management of patients. Importance of a multidisciplinary team cannot be underscored when dealing with specific causes of ON like infectious, neoplastic or certain paraneoplastic causes." @default.
- W3206696439 created "2021-10-25" @default.
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- W3206696439 date "2021-10-01" @default.
- W3206696439 modified "2023-09-25" @default.
- W3206696439 title "Demyelinating optic neuropathies – What every neurologist should know" @default.
- W3206696439 doi "https://doi.org/10.1016/j.jns.2021.117964" @default.
- W3206696439 hasPublicationYear "2021" @default.
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