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- W3206746293 endingPage "23" @default.
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- W3206746293 abstract "Celiac disease was once thought to affect people from European origin only but subsequently it was recognized that it affects Caucasians living in North America, Oceania, and even South America. Celiac disease is now known to affect non-Caucasian populations including Africans and Asians. Therefore, celiac disease has now become a global disease and it affects nearly one percent of world's population. Furthermore, a rise in both prevalence and incidence of celiac disease has been observed in many European countries and United States of America. Such a change in the epidemiology and better recognition of celiac disease has been possible because of following reasons. While making of diagnosis of celiac disease was much tedious in the past century, the diagnostic criteria are now much simplified with availability of reliable serological tests. It was believed that celiac disease was a disease of childhood but now, it is recognized that it affects people of any age group, including elderly. Furthermore, while it was believed that gluten hypersensitivity in celiac disease is limited to the small intestinal mucosa, there are now evidences suggesting that celiac disease is a systemic disease and it affects many other organs including skin, liver, bones and brain. Therefore, the spectrum of symptoms of celiac disease is wide including both gastrointestinal and extra-gastrointestinal. In this chapter, we have reviewed the epidemiology and clinical manifestations of celiac disease." @default.
- W3206746293 created "2021-10-25" @default.
- W3206746293 creator A5003395525 @default.
- W3206746293 creator A5059852221 @default.
- W3206746293 creator A5073213211 @default.
- W3206746293 date "2022-01-01" @default.
- W3206746293 modified "2023-09-26" @default.
- W3206746293 title "Epidemiology and clinical features of celiac disease in adults" @default.
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