FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3206869085> ?p ?o ?g. }

• W3206869085 abstract "Vancomycin is a first-line agent used in the treatment of methicillin-resistant Staphylococcus aureus; however, vancomycin is associated with acute kidney injury (AKI). Previous literature demonstrates decreased incidence of AKI using 24-h area under the concentration-time curve (AUC24) monitoring, but its safety is unknown in obese populations. Patients ≥18 years, with body mass indices (BMI) ≥30 kg/m2, admitted between August 2015 and July 2017 or October 2017 and September 2019, who received vancomycin for ≥72 h and had level(s) drawn within 96 h of initiation were included. The primary outcome was incidence of AKI. Secondary outcomes included inpatient mortality rate, median inpatient length of stay, median vancomycin trough concentration, and median vancomycin AUC24. AKI was identified using the highest serum creatinine value compared with the value immediately prior to vancomycin initiation based on Kidney Disease Improving Global Outcomes (KDIGO) criteria. Overall, 1,024 patients met inclusion criteria, with 142 out of 626 patients in the trough group and 65 out of 398 patients in the AUC24 group meeting criteria for AKI (22.7% versus 16.3%, P = 0.008). Logistic regression of the data to account for confounding factors maintained significance for the reduction in incidence of AKI with AUC24 monitoring compared to trough monitoring (P = 0.010). Monitoring of vancomycin with AUC24 was associated with a decreased risk of AKI when compared with trough monitoring in obese patients." @default.
• W3206869085 created "2021-10-25" @default.
• W3206869085 creator A5011798640 @default.
• W3206869085 creator A5012893972 @default.
• W3206869085 creator A5035351883 @default.
• W3206869085 creator A5043587292 @default.
• W3206869085 creator A5063936933 @default.
• W3206869085 creator A5067935460 @default.
• W3206869085 creator A5068175163 @default.
• W3206869085 creator A5085756859 @default.
• W3206869085 creator A5091561235 @default.
• W3206869085 date "2022-01-18" @default.
• W3206869085 modified "2023-10-15" @default.
• W3206869085 title "Acute Kidney Injury Associated with Area under the Curve versus Trough Monitoring of Vancomycin in Obese Patients" @default.
• W3206869085 cites W1825420268 @default.
• W3206869085 cites W1972725951 @default.
• W3206869085 cites W2005918477 @default.
• W3206869085 cites W2010066166 @default.
• W3206869085 cites W2011312924 @default.
• W3206869085 cites W2016821667 @default.
• W3206869085 cites W2028701043 @default.
• W3206869085 cites W2057605178 @default.
• W3206869085 cites W2128927279 @default.
• W3206869085 cites W2130499084 @default.
• W3206869085 cites W2131419242 @default.
• W3206869085 cites W2133120422 @default.
• W3206869085 cites W2133613588 @default.
• W3206869085 cites W2134099620 @default.
• W3206869085 cites W2138805439 @default.
• W3206869085 cites W2139937737 @default.
• W3206869085 cites W2144540367 @default.
• W3206869085 cites W2152771638 @default.
• W3206869085 cites W2737190756 @default.
• W3206869085 cites W2756233605 @default.
• W3206869085 cites W2774974184 @default.
• W3206869085 cites W2921011341 @default.
• W3206869085 cites W2952762910 @default.
• W3206869085 cites W2997749402 @default.
• W3206869085 cites W3012260518 @default.
• W3206869085 doi "https://doi.org/10.1128/aac.00886-21" @default.
• W3206869085 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34633843" @default.
• W3206869085 hasPublicationYear "2022" @default.
• W3206869085 type Work @default.
• W3206869085 sameAs 3206869085 @default.
• W3206869085 citedByCount "6" @default.
• W3206869085 countsByYear W32068690852022 @default.
• W3206869085 countsByYear W32068690852023 @default.
• W3206869085 crossrefType "journal-article" @default.
• W3206869085 hasAuthorship W3206869085A5011798640 @default.
• W3206869085 hasAuthorship W3206869085A5012893972 @default.
• W3206869085 hasAuthorship W3206869085A5035351883 @default.
• W3206869085 hasAuthorship W3206869085A5043587292 @default.
• W3206869085 hasAuthorship W3206869085A5063936933 @default.
• W3206869085 hasAuthorship W3206869085A5067935460 @default.
• W3206869085 hasAuthorship W3206869085A5068175163 @default.
• W3206869085 hasAuthorship W3206869085A5085756859 @default.
• W3206869085 hasAuthorship W3206869085A5091561235 @default.
• W3206869085 hasBestOaLocation W32068690852 @default.
• W3206869085 hasConcept C112705442 @default.
• W3206869085 hasConcept C120665830 @default.
• W3206869085 hasConcept C121332964 @default.
• W3206869085 hasConcept C126322002 @default.
• W3206869085 hasConcept C141071460 @default.
• W3206869085 hasConcept C159641895 @default.
• W3206869085 hasConcept C2778653478 @default.
• W3206869085 hasConcept C2778980435 @default.
• W3206869085 hasConcept C2779489039 @default.
• W3206869085 hasConcept C2780272996 @default.
• W3206869085 hasConcept C2780306776 @default.
• W3206869085 hasConcept C2780472472 @default.
• W3206869085 hasConcept C2909675724 @default.
• W3206869085 hasConcept C2910800852 @default.
• W3206869085 hasConcept C2911091166 @default.
• W3206869085 hasConcept C31785415 @default.
• W3206869085 hasConcept C523546767 @default.
• W3206869085 hasConcept C54355233 @default.
• W3206869085 hasConcept C61511704 @default.
• W3206869085 hasConcept C71924100 @default.
• W3206869085 hasConcept C77350462 @default.
• W3206869085 hasConcept C86803240 @default.
• W3206869085 hasConcept C90924648 @default.
• W3206869085 hasConceptScore W3206869085C112705442 @default.
• W3206869085 hasConceptScore W3206869085C120665830 @default.
• W3206869085 hasConceptScore W3206869085C121332964 @default.
• W3206869085 hasConceptScore W3206869085C126322002 @default.
• W3206869085 hasConceptScore W3206869085C141071460 @default.
• W3206869085 hasConceptScore W3206869085C159641895 @default.
• W3206869085 hasConceptScore W3206869085C2778653478 @default.
• W3206869085 hasConceptScore W3206869085C2778980435 @default.
• W3206869085 hasConceptScore W3206869085C2779489039 @default.
• W3206869085 hasConceptScore W3206869085C2780272996 @default.
• W3206869085 hasConceptScore W3206869085C2780306776 @default.
• W3206869085 hasConceptScore W3206869085C2780472472 @default.
• W3206869085 hasConceptScore W3206869085C2909675724 @default.
• W3206869085 hasConceptScore W3206869085C2910800852 @default.
• W3206869085 hasConceptScore W3206869085C2911091166 @default.
• W3206869085 hasConceptScore W3206869085C31785415 @default.
• W3206869085 hasConceptScore W3206869085C523546767 @default.
• W3206869085 hasConceptScore W3206869085C54355233 @default.
• W3206869085 hasConceptScore W3206869085C61511704 @default.

• next