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• W3206879504 startingPage "577746" @default.
• W3206879504 abstract "Appropriate immune response following COVID-19 vaccination is important in the context of disease-modifying treatments (DMTs). In a prospective cross-sectional study, we determined SARS-COV-2 IgG response up to 6 months following PfizerBNT162b2 vaccination in 414 multiple sclerosis (MS) patients and 89 healthy subjects. Protective response was demonstrated in untreated MS patients (N = 76, 100%), treated with Cladribine (N = 48, 100%), Dimethyl fumarate (N = 35, 100%), Natalizumab (N = 32, 100%), and Teriflunomide (N = 39, 100%), similarly to healthy subjects (N = 89, 97.8%). Response was decreased in Fingolimod (N = 42, 9.5%), Ocrelizumab (N = 114, 22.8%) and Alemtuzumab (N = 22, 86.4%) treated patients. IgG response can help tailor adequate vaccine guidelines for MS patients under various DMTs." @default.
• W3206879504 created "2021-10-25" @default.
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• W3206879504 date "2021-12-01" @default.
• W3206879504 modified "2023-10-04" @default.
• W3206879504 title "Humoral immune response in multiple sclerosis patients following PfizerBNT162b2 COVID19 vaccination: Up to 6 months cross-sectional study" @default.
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• W3206879504 doi "https://doi.org/10.1016/j.jneuroim.2021.577746" @default.
• W3206879504 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8500842" @default.
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