FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3207207151> ?p ?o ?g. }

• W3207207151 abstract "Anterior pituitary folliculostellate (FS) cells, first described almost 50 years ago, have a wide range of functions with respect to supporting and coordinating endocrine cell function, in particular through paracrine and gap junction-mediated signalling. Our previous studies identified the morphological organisation of FS cells, which mediates coordinated calcium activity throughout the homotypic FS network and allows signalling across the whole pituitary gland. It is also clear that FS cells can modify endocrine output and feedback on pituitary axes over a range of timescales. Recently, several studies have defined FS cells as a source of anterior pituitary endocrine cell renewal, which has resulted in a renaming of FS cells as Sox2+ve stem cells. Here, we highlight the broader potential of the FS cell population in fine-tuning and coordinating pituitary axes function. In addition, we identify a need for: the definition of the possible subtypes of FS cell and their relationship with the stem cell population; the potential role of FS cells in pulsatile hormone secretion and coordination of heterotypic cell networks; and the roles that FS cells may play in both early-life programming of pituitary axes and in memory, or anticipation, of demand. Further studies of FS cells may demonstrate the fundamental importance of this cell type and its potential as a therapeutic target to correct pituitary gland dysfunction, one of which is stem cell therapy. Clearly, a thorough understanding of all of these interactions and relationships of FS and endocrine cells is required whatever therapeutic use is suggested by their various roles." @default.
• W3207207151 created "2021-10-25" @default.
• W3207207151 creator A5046038903 @default.
• W3207207151 creator A5068539894 @default.
• W3207207151 date "2021-11-01" @default.
• W3207207151 modified "2023-10-14" @default.
• W3207207151 title "Renewing an old interest: Pituitary folliculostellate cells" @default.
• W3207207151 cites W13255964 @default.
• W3207207151 cites W1907946825 @default.
• W3207207151 cites W1970236236 @default.
• W3207207151 cites W1971535601 @default.
• W3207207151 cites W1976108889 @default.
• W3207207151 cites W1977282505 @default.
• W3207207151 cites W1980561052 @default.
• W3207207151 cites W1982225685 @default.
• W3207207151 cites W1983763042 @default.
• W3207207151 cites W1990493253 @default.
• W3207207151 cites W1993538394 @default.
• W3207207151 cites W1998486709 @default.
• W3207207151 cites W2004306126 @default.
• W3207207151 cites W2004317005 @default.
• W3207207151 cites W2004705965 @default.
• W3207207151 cites W2017671033 @default.
• W3207207151 cites W2023541046 @default.
• W3207207151 cites W2030441193 @default.
• W3207207151 cites W2030764815 @default.
• W3207207151 cites W2033212588 @default.
• W3207207151 cites W2033453532 @default.
• W3207207151 cites W2039704315 @default.
• W3207207151 cites W2043681581 @default.
• W3207207151 cites W2048519135 @default.
• W3207207151 cites W2049832435 @default.
• W3207207151 cites W2049887628 @default.
• W3207207151 cites W2050082848 @default.
• W3207207151 cites W2059433119 @default.
• W3207207151 cites W2063606263 @default.
• W3207207151 cites W2064252232 @default.
• W3207207151 cites W2065291965 @default.
• W3207207151 cites W2068193270 @default.
• W3207207151 cites W2074499459 @default.
• W3207207151 cites W2085529450 @default.
• W3207207151 cites W2088019196 @default.
• W3207207151 cites W2091446981 @default.
• W3207207151 cites W2097011292 @default.
• W3207207151 cites W2099543786 @default.
• W3207207151 cites W2100563340 @default.
• W3207207151 cites W2101041865 @default.
• W3207207151 cites W2103601809 @default.
• W3207207151 cites W2114687358 @default.
• W3207207151 cites W2121978115 @default.
• W3207207151 cites W2130093713 @default.
• W3207207151 cites W2134301263 @default.
• W3207207151 cites W2142439816 @default.
• W3207207151 cites W2149474466 @default.
• W3207207151 cites W2149658732 @default.
• W3207207151 cites W2158729939 @default.
• W3207207151 cites W2160150702 @default.
• W3207207151 cites W2162790369 @default.
• W3207207151 cites W2164146931 @default.
• W3207207151 cites W2214901408 @default.
• W3207207151 cites W2276759797 @default.
• W3207207151 cites W2293809486 @default.
• W3207207151 cites W2336327114 @default.
• W3207207151 cites W2443705897 @default.
• W3207207151 cites W2551785135 @default.
• W3207207151 cites W2594069813 @default.
• W3207207151 cites W2620749312 @default.
• W3207207151 cites W2883735573 @default.
• W3207207151 cites W2897516360 @default.
• W3207207151 cites W2901061451 @default.
• W3207207151 cites W2969895325 @default.
• W3207207151 cites W2971219844 @default.
• W3207207151 cites W2999662363 @default.
• W3207207151 cites W3010746525 @default.
• W3207207151 cites W3014706241 @default.
• W3207207151 cites W3024204266 @default.
• W3207207151 cites W3118608929 @default.
• W3207207151 cites W3118784694 @default.
• W3207207151 cites W3128744660 @default.
• W3207207151 cites W3135972711 @default.
• W3207207151 cites W3170827540 @default.
• W3207207151 cites W3199480526 @default.
• W3207207151 cites W42080332 @default.
• W3207207151 doi "https://doi.org/10.1111/jne.13053" @default.
• W3207207151 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34734454" @default.
• W3207207151 hasPublicationYear "2021" @default.
• W3207207151 type Work @default.
• W3207207151 sameAs 3207207151 @default.
• W3207207151 citedByCount "12" @default.
• W3207207151 countsByYear W32072071512021 @default.
• W3207207151 countsByYear W32072071512022 @default.
• W3207207151 countsByYear W32072071512023 @default.
• W3207207151 crossrefType "journal-article" @default.
• W3207207151 hasAuthorship W3207207151A5046038903 @default.
• W3207207151 hasAuthorship W3207207151A5068539894 @default.
• W3207207151 hasBestOaLocation W32072071511 @default.
• W3207207151 hasConcept C103395026 @default.
• W3207207151 hasConcept C104317684 @default.
• W3207207151 hasConcept C126322002 @default.
• W3207207151 hasConcept C134018914 @default.

• next