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• W3207381844 abstract "Motivated by the sidewise motions of dynein motors shown in experiments, we use a variant of the exclusion process to model the multistep dynamics of dyneins on a cylinder with open ends. Due to the varied step sizes of the particles in a quasi-two-dimensional topology, we observe the emergence of a novel phase diagram depending on the various load conditions. Under high-load conditions, our numerical findings yield results similar to the TASEP model with the presence of all three standard TASEP phases, namely the low-density (LD), high-density (HD), and maximal-current (MC) phases. However, for medium- to low-load conditions, for all chosen influx and outflux rates, we only observe the LD and HD phases, and the maximal-current phase disappears. Further, we also measure the dynamics for a single dynein particle which is logarithmically slower than a TASEP particle with a shorter waiting time. Our results also confirm experimental observations of the dwell time distribution: The dwell time distribution for dyneins is exponential in less crowded conditions, whereas a double exponential emerges under overcrowded conditions." @default.
• W3207381844 created "2021-10-25" @default.
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• W3207381844 date "2021-10-14" @default.
• W3207381844 modified "2023-10-10" @default.
• W3207381844 title "Dynein-Inspired Multilane Exclusion Process with Open Boundary Conditions" @default.
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• W3207381844 doi "https://doi.org/10.3390/e23101343" @default.
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