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- W3207443518 abstract "Despite therapeutic advances, lung cancer remains a leading cause of cancer death worldwide. Nectin-4, a cell adhesion molecule, is highly expressed in several epithelial tumor types, including non-small cell lung cancer (NSCLC). Targeting Nectin-4 in NSCLC provides a novel treatment approach. Enfortumab vedotin (EV) is an antibody-drug conjugate comprised of a fully human monoclonal antibody directed against Nectin-4, and monomethyl auristatin E (MMAE), a microtubule-disrupting agent, attached to the antibody via a protease-cleavable linker." @default.
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- W3207443518 date "2021-10-01" @default.
- W3207443518 modified "2023-09-30" @default.
- W3207443518 title "P47.02 EV-202: Phase 2 Study of Enfortumab Vedotin for Previously Treated Advanced Solid Tumors Including Non-Small Cell Lung Cancer" @default.
- W3207443518 doi "https://doi.org/10.1016/j.jtho.2021.08.495" @default.
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