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• W3207498001 startingPage "1084" @default.
• W3207498001 abstract "Background and objectives: Although the role of the gut microbiome in type 2 diabetes (T2D) pathophysiology is evident, current systematic reviews and meta-analyses analyzing T2D treatment mainly focus on metabolic outcomes. The objective of this study is to evaluate the microbiome and metabolic changes after different types of treatment in T2D patients. Materials and Methods: A systematic search of PubMed, Wiley online library, Science Direct, and Cochrane library electronic databases was performed. Randomized controlled clinical trials published in the last five years that included T2D subjects and evaluated the composition of the gut microbiome alongside metabolic outcomes before and after conventional or alternative glucose lowering therapy were selected. Microbiome changes were evaluated alongside metabolic outcomes in terms of bacteria taxonomic hierarchy, intestinal flora biodiversity, and applied intervention. Results: A total of 16 eligible studies involving 1301 participants were reviewed. Four trials investigated oral glucose-lowering treatment, three studies implemented bariatric surgery, and the rest analyzed probiotic, prebiotic, or synbiotic effects. The most common alterations were increased abundance of Firmicutes and Proteobacteria parallel to improved glycemic control. Bariatric surgery, especially Roux-en-Y gastric bypass, led to the highest variety of changed bacteria phyla. Lower diversity post-treatment was the most significant biodiversity result, which was present with improved glycemic control. Conclusions: Anti-diabetic treatment induced the growth of depleted bacteria. A gut microbiome similar to healthy individuals was achieved during some trials. Further research must explore the most effective strategies to promote beneficial bacteria, lower diversity, and eventually reach a non-T2D microbiome." @default.
• W3207498001 created "2021-10-25" @default.
• W3207498001 creator A5003022831 @default.
• W3207498001 creator A5028760362 @default.
• W3207498001 creator A5052940351 @default.
• W3207498001 creator A5070755287 @default.
• W3207498001 date "2021-10-11" @default.
• W3207498001 modified "2023-09-27" @default.
• W3207498001 title "Microbiome Changes after Type 2 Diabetes Treatment: A Systematic Review" @default.
• W3207498001 cites W1589649796 @default.
• W3207498001 cites W190681677 @default.
• W3207498001 cites W1928552205 @default.
• W3207498001 cites W1966921473 @default.
• W3207498001 cites W1977968392 @default.
• W3207498001 cites W1984993963 @default.
• W3207498001 cites W2004549986 @default.
• W3207498001 cites W2023615726 @default.
• W3207498001 cites W2032230795 @default.
• W3207498001 cites W2042945103 @default.
• W3207498001 cites W2045731464 @default.
• W3207498001 cites W2071841602 @default.
• W3207498001 cites W2098450342 @default.
• W3207498001 cites W2104660451 @default.
• W3207498001 cites W2105786204 @default.
• W3207498001 cites W2111317067 @default.
• W3207498001 cites W2115763995 @default.
• W3207498001 cites W2118629634 @default.
• W3207498001 cites W2135989088 @default.
• W3207498001 cites W2136417551 @default.
• W3207498001 cites W2139334262 @default.
• W3207498001 cites W2145232186 @default.
• W3207498001 cites W2151158627 @default.
• W3207498001 cites W2155185912 @default.
• W3207498001 cites W2156098321 @default.
• W3207498001 cites W2175465469 @default.
• W3207498001 cites W2188930066 @default.
• W3207498001 cites W2206854629 @default.
• W3207498001 cites W2229090956 @default.
• W3207498001 cites W2267861477 @default.
• W3207498001 cites W2267973470 @default.
• W3207498001 cites W2301014044 @default.
• W3207498001 cites W2326116909 @default.
• W3207498001 cites W2337509055 @default.
• W3207498001 cites W2529872601 @default.
• W3207498001 cites W2531245466 @default.
• W3207498001 cites W2547640677 @default.
• W3207498001 cites W2550084345 @default.
• W3207498001 cites W2552998515 @default.
• W3207498001 cites W2557717486 @default.
• W3207498001 cites W2564875216 @default.
• W3207498001 cites W2565507590 @default.
• W3207498001 cites W2570895990 @default.
• W3207498001 cites W2592913662 @default.
• W3207498001 cites W2594496173 @default.
• W3207498001 cites W2605506963 @default.
• W3207498001 cites W2606953164 @default.
• W3207498001 cites W2617940752 @default.
• W3207498001 cites W2620617458 @default.
• W3207498001 cites W2743633434 @default.
• W3207498001 cites W2755198076 @default.
• W3207498001 cites W2755757727 @default.
• W3207498001 cites W2756205717 @default.
• W3207498001 cites W2756853277 @default.
• W3207498001 cites W2770902662 @default.
• W3207498001 cites W2782981060 @default.
• W3207498001 cites W2783242163 @default.
• W3207498001 cites W2799404142 @default.
• W3207498001 cites W2800873859 @default.
• W3207498001 cites W2802229234 @default.
• W3207498001 cites W2803132482 @default.
• W3207498001 cites W2887694500 @default.
• W3207498001 cites W2889977344 @default.
• W3207498001 cites W2894104063 @default.
• W3207498001 cites W2898587007 @default.
• W3207498001 cites W2899856354 @default.
• W3207498001 cites W2903351370 @default.
• W3207498001 cites W2904078035 @default.
• W3207498001 cites W2909668868 @default.
• W3207498001 cites W2914162057 @default.
• W3207498001 cites W2923286275 @default.
• W3207498001 cites W2943320595 @default.
• W3207498001 cites W2947601525 @default.
• W3207498001 cites W2954472346 @default.
• W3207498001 cites W2955245188 @default.
• W3207498001 cites W2970684805 @default.
• W3207498001 cites W2970965419 @default.
• W3207498001 cites W2972869264 @default.
• W3207498001 cites W2982297198 @default.
• W3207498001 cites W2991196595 @default.
• W3207498001 cites W2991792334 @default.
• W3207498001 cites W2998420978 @default.
• W3207498001 cites W3007815550 @default.
• W3207498001 cites W3016114396 @default.
• W3207498001 cites W3022903699 @default.
• W3207498001 cites W3025320509 @default.
• W3207498001 cites W3034349978 @default.
• W3207498001 cites W3046523882 @default.
• W3207498001 cites W3092470446 @default.

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