FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3207560797> ?p ?o ?g. }

• W3207560797 endingPage "1283" @default.
• W3207560797 startingPage "1283" @default.
• W3207560797 abstract "Antimicrobial resistance (AMR) remains one of the greatest public health-perturbing crises of the 21st century, where species have evolved a myriad of defence strategies to resist conventional therapy. The production of extended-spectrum β-lactamase (ESBL), AmpC and carbapenemases in Gram-negative bacteria (GNB) is one such mechanism that currently poses a significant threat to the continuity of first-line and last-line β-lactam agents, where multi-drug-resistant GNB currently warrant a pandemic on their own merit. The World Health Organisation (WHO) has long recognised the need for an improved and coordinated global effort to contain these pathogens, where two factors in particular, international travel and exposure to antimicrobials, play an important role in the emergence and dissemination of antibiotic-resistant genes. Studies described herein assess the resistance patterns of isolated nosocomial pathogens, where levels of resistance were detected using recognised in vitro methods. Additionally, studies conducted extensively investigated alternative biocide (namely peracetic acid, triameen and benzalkonium chloride) and therapeutic options (specifically 1,10-phenanthroline-5,6-dione), where the levels of induced endotoxin from E. coli were also studied for the latter. Antibiotic susceptibility testing revealed there was a significant association between multi-drug resistance and ESBL production, where the WHO critical-priority pathogens, namely E. coli, K. pneumoniae, A. baumannii and P. aeruginosa, exhibited among the greatest levels of multi-drug resistance. Novel compound 1,10-phenanthroline-5,6-dione (phendione) shows promising antimicrobial activity, with MICs determined for all bacterial species, where levels of induced endotoxin varied depending on the concentration used. Tested biocide agents show potential to act as intermediate-level disinfectants in hospital settings, where all tested clinical isolates were susceptible to treatment." @default.
• W3207560797 created "2021-10-25" @default.
• W3207560797 creator A5012598466 @default.
• W3207560797 creator A5036960617 @default.
• W3207560797 creator A5072014143 @default.
• W3207560797 date "2021-10-21" @default.
• W3207560797 modified "2023-10-02" @default.
• W3207560797 title "Effective Antimicrobial Solutions for Eradicating Multi-Resistant and β-Lactamase-Producing Nosocomial Gram-Negative Pathogens" @default.
• W3207560797 cites W2101037019 @default.
• W3207560797 cites W2159869976 @default.
• W3207560797 cites W2167939529 @default.
• W3207560797 cites W2248169544 @default.
• W3207560797 cites W2342024658 @default.
• W3207560797 cites W2498876603 @default.
• W3207560797 cites W2537779462 @default.
• W3207560797 cites W2611885760 @default.
• W3207560797 cites W2749137552 @default.
• W3207560797 cites W2789345104 @default.
• W3207560797 cites W2888013574 @default.
• W3207560797 cites W2894615051 @default.
• W3207560797 cites W2941914274 @default.
• W3207560797 cites W2949657384 @default.
• W3207560797 cites W2993797120 @default.
• W3207560797 cites W3001288987 @default.
• W3207560797 cites W3006452222 @default.
• W3207560797 cites W3008897713 @default.
• W3207560797 cites W3043733274 @default.
• W3207560797 cites W3046891347 @default.
• W3207560797 cites W3075820966 @default.
• W3207560797 cites W3093499299 @default.
• W3207560797 cites W3097365164 @default.
• W3207560797 cites W3108847796 @default.
• W3207560797 cites W3124198324 @default.
• W3207560797 cites W3133094790 @default.
• W3207560797 cites W3152796170 @default.
• W3207560797 cites W3154331852 @default.
• W3207560797 cites W3156664360 @default.
• W3207560797 cites W3158566457 @default.
• W3207560797 cites W3159592417 @default.
• W3207560797 cites W3160098832 @default.
• W3207560797 cites W3160739757 @default.
• W3207560797 cites W3179099464 @default.
• W3207560797 cites W3185735703 @default.
• W3207560797 cites W3196187656 @default.
• W3207560797 cites W647595908 @default.
• W3207560797 doi "https://doi.org/10.3390/antibiotics10111283" @default.
• W3207560797 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8614872" @default.
• W3207560797 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34827221" @default.
• W3207560797 hasPublicationYear "2021" @default.
• W3207560797 type Work @default.
• W3207560797 sameAs 3207560797 @default.
• W3207560797 citedByCount "7" @default.
• W3207560797 countsByYear W32075607972022 @default.
• W3207560797 countsByYear W32075607972023 @default.
• W3207560797 crossrefType "journal-article" @default.
• W3207560797 hasAuthorship W3207560797A5012598466 @default.
• W3207560797 hasAuthorship W3207560797A5036960617 @default.
• W3207560797 hasAuthorship W3207560797A5072014143 @default.
• W3207560797 hasBestOaLocation W32075607971 @default.
• W3207560797 hasConcept C114851261 @default.
• W3207560797 hasConcept C142724271 @default.
• W3207560797 hasConcept C197471484 @default.
• W3207560797 hasConcept C4937899 @default.
• W3207560797 hasConcept C501593827 @default.
• W3207560797 hasConcept C71924100 @default.
• W3207560797 hasConcept C86803240 @default.
• W3207560797 hasConcept C89423630 @default.
• W3207560797 hasConcept C94665300 @default.
• W3207560797 hasConceptScore W3207560797C114851261 @default.
• W3207560797 hasConceptScore W3207560797C142724271 @default.
• W3207560797 hasConceptScore W3207560797C197471484 @default.
• W3207560797 hasConceptScore W3207560797C4937899 @default.
• W3207560797 hasConceptScore W3207560797C501593827 @default.
• W3207560797 hasConceptScore W3207560797C71924100 @default.
• W3207560797 hasConceptScore W3207560797C86803240 @default.
• W3207560797 hasConceptScore W3207560797C89423630 @default.
• W3207560797 hasConceptScore W3207560797C94665300 @default.
• W3207560797 hasIssue "11" @default.
• W3207560797 hasLocation W32075607971 @default.
• W3207560797 hasLocation W32075607972 @default.
• W3207560797 hasLocation W32075607973 @default.
• W3207560797 hasLocation W32075607974 @default.
• W3207560797 hasOpenAccess W3207560797 @default.
• W3207560797 hasPrimaryLocation W32075607971 @default.
• W3207560797 hasRelatedWork W2117107335 @default.
• W3207560797 hasRelatedWork W2138029876 @default.
• W3207560797 hasRelatedWork W2318509744 @default.
• W3207560797 hasRelatedWork W2401291924 @default.
• W3207560797 hasRelatedWork W2907284219 @default.
• W3207560797 hasRelatedWork W2946874241 @default.
• W3207560797 hasRelatedWork W3128949511 @default.
• W3207560797 hasRelatedWork W4285542024 @default.
• W3207560797 hasRelatedWork W851687779 @default.
• W3207560797 hasRelatedWork W2292265946 @default.
• W3207560797 hasVolume "10" @default.
• W3207560797 isParatext "false" @default.
• W3207560797 isRetracted "false" @default.
• W3207560797 magId "3207560797" @default.

• next